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Barth syndrome (BTHS) is a rare but serious X-linked genetic disorder, caused by changes in phospholipid structure and metabolism. It may affect multiple body systems, and is potentially fatal. The syndrome is diagnosed almost exclusively in males.
Alpha cells (α-cells) are endocrine cells that are found in the Islets of Langerhans in the pancreas. Alpha cells secrete the peptide hormone glucagon in order to increase glucose levels in the blood stream.
A liposome is a small artificial vesicle, spherical in shape, having at least one lipid bilayer. Due to their hydrophobicity and/or hydrophilicity, biocompatibility, particle size and many other properties, liposomes can be used as drug delivery vehicles for administration of pharmaceutical drugs and nutrients, such as lipid nanoparticles in mRNA vaccines, and DNA vaccines. Liposomes can be prepared by disrupting biological membranes.
Lipid peroxidation, or lipid oxidation, is a complex chemical process that leads to oxidative degradation of lipids, resulting in the formation of peroxide and hydroperoxide derivatives. It occurs when free radicals, specifically reactive oxygen species (ROS), interact with lipids within cell membranes, typically polyunsaturated fatty acids (PUFAs) as they have carbon–carbon double bonds. This reaction leads to the formation of lipid radicals, collectively referred to as lipid peroxides or lipid oxidation products (LOPs), which in turn react with other oxidizing agents, leading to a chain reaction that results in oxidative stress and cell damage.
Phosphatidylinositol or inositol phospholipid is a biomolecule. It was initially called "inosite" when it was discovered by Léon Maquenne and Johann Joseph von Scherer in the late 19th century. It was discovered in bacteria but later also found in eukaryotes, and was found to be a signaling molecule.
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N-Arachidonoyl dopamine (NADA) is an endocannabinoid that acts as an agonist of the CB1 receptor and the transient receptor potential V1 (TRPV1) ion channel. NADA was first described as a putative endocannabinoid (agonist for the CB1 receptor) in 2000 and was subsequently identified as an endovanilloid (agonist for TRPV1) in 2002. NADA is an endogenous arachidonic acid based lipid found in the brain of rats, with especially high concentrations in the hippocampus, cerebellum, and striatum. It activates the TRPV1 channel with an EC50 of approximately of 50 nM which makes it the putative endogenous TRPV1 agonist.
Aldo, Giovanni e Giacomo are an Italian trio of comedians, actors, directors and screenwriters, comprising Aldo Baglio, Giovanni Storti and Giacomo Poretti. They have performed in movies, theatres, and television, and are well known in Italy.
Acyl-CoA:lysocardiolipin acyltransferase-1 (ALCAT1) is a polyglycerophospholipid acyltransferase of the endoplasmic reticulum which is primarily known for catalyzing the acylation of monolysocardiolipin back into cardiolipin, although it does catalyze the acylation of other polyglycerophospholipids.
Zero Comico is an Italian video game published in 2001 and dedicated to the characters of Aldo, Giovanni and Giacomo, with numerous references to their shows and parodies of other video games. It is distributed by Medusa Games, part of Medusa Film, distributor of the trio's films. In the game Aldo, Giovanni and Giacomo are voiced by themselves. The game is imbued with the comedy of the trio and also with some lines already used in theatrical performances.
I Hate Summer is a 2020 Italian comedy film directed by Massimo Venier and starring Aldo, Giovanni & Giacomo.
Carotenoid complexes are physical associations of carotenoids with other molecules.
References
- ↑ "I rischi del tafazzismo". ilGiornale.it (in Italian). 2022-01-27. Retrieved 2022-06-22.
- ↑ Schlame, Michael; Xu, Yang (2020-08-21). "The Function of Tafazzin, a Mitochondrial Phospholipid–Lysophospholipid Acyltransferase". Journal of Molecular Biology. Molecular Mechanisms in Integral Membrane Enzymology. 432 (18): 5043–5051. doi:10.1016/j.jmb.2020.03.026. ISSN 0022-2836. PMC 7483898 . PMID 32234310.
- ↑ Corcelli, Angela; Schlame, Michael (2016-06-01). "Cardiolipin as key lipid of mitochondria in health and disease. 2nd Edition, Florence, Italy, September 30–October 1, 2015". Chemistry and Physics of Lipids. 198: 10–12. doi:10.1016/j.chemphyslip.2016.04.005. ISSN 0009-3084. PMID 27132118.
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