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Thalidomide, sold under the brand names Contergan and Thalomid among others, is a medication used to treat a number of cancers, graft-versus-host disease, and a number of skin conditions including complications of leprosy. While it has been used in a number of HIV-associated conditions, such use is associated with increased levels of the virus. It is administered orally.
Kate Elizabeth Winslet is an English actress. Known for her work in independent films, particularly period dramas, as well as for her portrayals of headstrong, complicated women, she has received numerous accolades, including an Academy Award, a Grammy Award, two Primetime Emmy Awards, three British Academy Film Awards, and five Golden Globe Awards.
Andrew Lloyd Webber, Baron Lloyd-Webber, is an English composer and impresario of musical theatre. Several of his musicals have run for more than a decade both in the West End and on Broadway. He has composed 21 musicals, a song cycle, a set of variations, two film scores, and a Latin Requiem Mass. Several of his songs have been widely recorded and were successful outside of their parent musicals, such as "Memory" from Cats, "The Music of the Night" and "All I Ask of You" from The Phantom of the Opera, "I Don't Know How to Love Him" from Jesus Christ Superstar, "Don't Cry for Me Argentina" from Evita, and "Any Dream Will Do" from Joseph and the Amazing Technicolor Dreamcoat. In 2001, The New York Times referred him as "the most commercially successful composer in history". The Daily Telegraph ranked him the "fifth most powerful person in British culture" in 2008, with lyricist Don Black writing "Andrew more or less single-handedly reinvented the musical."
Phocomelia is a condition that involves malformations of human arms and legs. Although many factors can cause phocomelia, the prominent roots come from the use of the drug thalidomide and from genetic inheritance.
Geoffrey Roy Rush is an Australian actor and narrator. He is among 24 people who have won the Triple Crown of Acting: an Academy Award for film, a Primetime Emmy Award for television, and a Tony Award for theatre.
Sir Samuel Alexander Mendes is a British film and stage director, producer, and screenwriter. In theatre, he is known for his dark re-inventions of the stage musicals Cabaret (1993), Oliver! (1994), Company (1995), and Gypsy (2003). He directed an original West End stage musical for the first time with Charlie and the Chocolate Factory (2013). For directing the play The Ferryman, Mendes was awarded the Tony Award for Best Direction of a Play in 2019.
Sir Nigel Ross Playfair was an English actor and director, known particularly as actor-manager of the Lyric Theatre, Hammersmith, in the 1920s.
Metrosexuality is a British television comedy-drama, which aired on Channel 4 in 2001 as a short-run series of six episodes. It was later re-edited into a single feature for DVD release by TLA Releasing. It depicts the interactions of a racially and sexually diverse group of friends and family living in Notting Hill.
This is a summary of 2005 in music in the United Kingdom.
Mat Fraser is an English rock musician, actor, writer and performance artist. He has thalidomide-induced phocomelia. In 2017, he was cast to play Shakespeare's Richard III at the Hull Truck Theatre as part of Hull City of Culture 2017.
Alison Fraser is an American actress, voice actress and singer who has appeared on Broadway, Off-Broadway, and in television and film. In concert, she has performed at such venues as Carnegie Hall, The White House, Town Hall, The Brooklyn Botanic Garden, The Tisch Center for the Arts, The Folger Shakespeare Library, The Wilma, The Emelin, Joe's Pub, 54 Below, and Symphony Space.
Richard James Lumsden is an English actor, writer, composer and musician. He played Nathan in Channel 4's drama Sugar Rush and on radio he plays Ray in Clare in the Community.
Sheila Mary Fraser was an English actress. She is best known for her roles in the television serial A Family at War (1970–1971) and as Luke Skywalker's aunt Beru in Star Wars (1977).
In the late 1950s and early 1960s, the use of thalidomide in 46 countries by women who were pregnant or who subsequently became pregnant, resulted in the "biggest man‐made medical disaster ever," resulting in more than 10,000 children born with a range of severe deformities, such as phocomelia, as well as thousands of miscarriages.
Cast Offs is a BAFTA-nominated comedy-drama mockumentary that follows a group of six disabled people sent to a remote British Island for a fictional reality show.
Matilda the Musical is a musical based on the 1988 children's novel of the same name by Roald Dahl. It was adapted by Dennis Kelly, with music and lyrics by Tim Minchin and directed for the stage by Matthew Warchus. The musical's narrative centres on Matilda, a precocious 5-year-old girl with the gift of telekinesis, who loves reading, overcomes obstacles caused by her family and school, and helps her teacher to reclaim her life. After a twelve-week trial run staged by the Royal Shakespeare Company (RSC) at Stratford-upon-Avon from November 2010 to January 2011, it received its West End premiere on 24 November 2011 at the Cambridge Theatre and its Broadway premiere on 11 April 2013 at the Shubert Theatre.
Stanislaus Berent was an American freak who performed at many freak shows, including the World Circus Sideshow in 1941 under the stage name of Sealo the Seal Boy. He was known for his seal-like arms, which were caused by a congenital medical condition known as phocomelia. In 2001, Mat Fraser's play inspired by Sealo called Sealboy: Freak debuted.
Mare of Easttown is an American crime drama limited series created by Brad Ingelsby for HBO. Directed by Craig Zobel and written by Ingelsby, the series premiered on April 18, 2021, and concluded on May 30, 2021, consisting of seven episodes. It stars Kate Winslet as the title character, a detective investigating a murder in a small town near Philadelphia. Julianne Nicholson, Jean Smart, Angourie Rice, Evan Peters, Sosie Bacon, David Denman, Neal Huff, James McArdle, Guy Pearce, Cailee Spaeny, John Douglas Thompson, and Joe Tippett appear in supporting roles.
Ammonite is a 2020 romantic drama film written and directed by Francis Lee. The film is loosely inspired by the life of British palaeontologist Mary Anning, played by Kate Winslet. The film centres on a speculative romantic relationship between Anning and Charlotte Murchison, played by Saoirse Ronan. Gemma Jones, James McArdle, Alec Secăreanu and Fiona Shaw also star.
References
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