Thomas E. Scammell is an American neurologist, known for his research in sleep medicine pertaining to neurobiology of sleep and sleep disorders, particularly narcolepsy and cataplexy. Scammell is a professor of neurology at Harvard Medical School, serving the department of neurology at Beth Israel Deaconess Medical Center and Boston Children's Hospital. [1]
Scammell completed his Bachelor of Science degree in neuroscience from the University of Rochester in 1984. He then pursued a Doctor of Medicine degree from the University of Massachusetts Medical School, which he obtained in 1988. [2]
Scammell has primarily focused on the neurological aspects of sleep and associated disorders. As a healthcare provider, he practices at the Beth Israel Deaconess Medical Center in Boston, Massachusetts. He is also affiliated with Boston Children's Hospital. [3]
In addition to his clinical work, Scammell has served as a professor at Harvard Medical School since 2012, where he has a laboratory which conducts research on the neurobiology of sleep and the neural basis of sleep disorders such as narcolepsy [4] and cataplexy. [5] He is an editor of SLEEP. [2]
Scammell's work has elucidated the molecular genetics of sleep regulation and the critical role of various hypothalamic pathways in sleep and circadian rhythms. [6] [7]
Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area in Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States. Unlike most other leading medical schools, HMS does not operate in conjunction with a single hospital but is directly affiliated with several teaching hospitals in the Boston area. Affiliated teaching hospitals and research institutes include Dana–Farber Cancer Institute, Massachusetts General Hospital, Brigham and Women's Hospital, Beth Israel Deaconess Medical Center, Boston Children's Hospital, McLean Hospital, Cambridge Health Alliance, The Baker Center for Children and Families, and Spaulding Rehabilitation Hospital.
Alvaro Pascual-Leone is a Spanish-American Professor of Neurology at Harvard Medical School, with which he has been affiliated since 1997. He is currently a Senior Scientist at the Hinda and Arthur Marcus Institute for Aging Research at Hebrew SeniorLife. He was previously the Director of the Berenson-Allen Center for Noninvasive Brain Stimulation and Program Director of the Harvard-Thorndike Clinical Research Center of the Beth Israel Deaconess Medical Center in Boston.
Beth Israel Deaconess Medical Center (BIDMC) in Boston, Massachusetts is a teaching hospital of Harvard Medical School. It was formed out of the 1996 merger of Beth Israel Hospital and New England Deaconess Hospital. Among independent teaching hospitals, Beth Israel Deaconess Medical Center consistently ranks in the top three recipients of biomedical research funding from the National Institutes of Health. Research funding totals nearly $200 million annually. BIDMC researchers run more than 850 active sponsored projects and 200 clinical trials. The Harvard-Thorndike General Clinical Research Center, the oldest clinical research laboratory in the United States, has been located on this site since 1973.
Cataplexy is a sudden and transient episode of muscle weakness accompanied by full conscious awareness, typically triggered by emotions such as laughing, crying, or terror. Cataplexy affects approximately 20% of people who have narcolepsy, and is caused by an autoimmune destruction of hypothalamic neurons that produce the neuropeptide hypocretin, which regulates arousal and has a role in stabilization of the transition between wake and sleep states. Cataplexy without narcolepsy is rare and the cause is unknown.
New England Baptist Hospital (NEBH) is a 141-bed adult medical-surgical hospital in Boston, Massachusetts specializing in orthopedic care and complex orthopedic procedures. NEBH is an international leader in the treatment of all forms of musculoskeletal disorders and diseases.
The Lahey Hospital & Medical Center, formerly known as the Lahey Clinic, is a physician-led nonprofit teaching hospital of Tufts University School of Medicine based in Burlington, Massachusetts. The hospital was founded in Boston in 1923 by surgeon Frank H. Lahey, M.D., and is managed by Beth Israel Lahey Health. U.S. News & World Report has cited it several times on its list of "America's Best Hospitals" in the category of urology.
Dr. David D. Ginty is an American neuroscientist and developmental biologist.
Louis R. Caplan is an American physician who is a senior member of the Division of Cerebrovascular Disease at Beth Israel Deaconess Medical Center, Boston. He is a Professor of Neurology at Harvard Medical School, Boston, and the founder of the Harvard Stroke Registry at Beth Israel Deaconess Medical Center. Caplan is the author or editor of 51 books and more than 700 articles in medical journals.
Narcolepsy is a chronic neurological disorder that involves a decreased ability to regulate sleep–wake cycles. Symptoms often include periods of excessive daytime sleepiness and brief involuntary sleep episodes. About 70% of those affected also experience episodes of sudden loss of muscle strength, known as cataplexy. Narcolepsy paired with cataplexy is evidenced to be an autoimmune disorder. These experiences of cataplexy can be brought on by strong emotions. Less commonly, there may be vivid hallucinations or an inability to move while falling asleep or waking up. People with narcolepsy tend to sleep about the same number of hours per day as people without, but the quality of sleep tends to be lessened.
Wade G. Regehr is a Professor of Neurobiology at Harvard Medical School's Department of Neurobiology.
Clifford J. Woolf is professor of neurology and neurobiology at Harvard Medical School and director of the F.M. Kirby Neurobiology Center at Boston Children’s Hospital. He has added greatly to the understanding of pain.
Emmanuel Mignot is a sleep researcher and director of the Stanford Center for Sleep Sciences and Medicine, at Stanford University. Dr. Mignot is an authority on sleep research and medicine, and is mostly known for his work on narcolepsy. He is the Craig Reynolds Professor of Sleep Medicine at Stanford Medical School, Stanford University.
Mitchell T. Rabkin is an American physician and Distinguished Institute Scholar at the Shapiro Institute, Professor of Medicine at Harvard Medical School and CEO Emeritus at the Beth Israel Deaconess Medical Center.
Rajiv Ratan is an Indian American academic, professor, administrator and scientist based in New York. He is the Burke Professor of Neurology and Neuroscience at Weill Cornell Medicine. Since 2003, he has served as the executive director of Burke Neurological Institute and as a member of the Council of Affiliated Deans of Weill Cornell Medicine.
The Department of Neurobiology at Harvard Medical School is located in the Longwood Medical Area of Boston, MA. It is consistently ranked as one of the top programs in Neurobiology and behavior in the world. The Department is part of the Basic Research Program at Harvard Medical School, with research pertaining to development of the nervous system, sensory neuroscience, neurophysiology, and behavior. The Department was founded by Stephen W. Kuffler in 1966, the first department dedicated to Neurobiology in the world. The mission of the Department is “to understand the workings of the brain through basic research and to use that knowledge to work toward preventive and therapeutic methods that alleviate neurological diseases”.
Judy Shih-Hwa Liu is the Sidney A. Fox and Dorothea Doctors Fox Professor of Ophthalmology and Neuroscience at Brown University. She works on the cortical malformations that cause epilepsy.
Albert Mark Galaburda is a cognitive and behavioral neurologist with a special focus on the biologic bases of developmental cognitive disorders. He is the Emily Fisher Landau Professor of Neurology and Neuroscience at Harvard Medical School, the Director of the Office for Diversity, Inclusion, and Career Advancement at Beth Israel Deaconess Medical Center, Boston, and co-director of the Harvard University Interfaculty Initiative on Mind Brain and Behavior, together with psychologist Alfonso Caramazza. He is best known for his development of the Geschwind–Galaburda hypothesis, which helps explain differences in cognitive abilities on the basis of sex hormones and immunological characteristics and their relationship to lateralization of brain function, as well as for his pioneering studies on the biological foundations of developmental dyslexia. Other work includes the anatomical organization of the auditory cortex in the brains of monkeys and humans and the neuroanatomical and neurodevelopmental bases of brain laterality and asymmetry. He attended the Six-Year Liberal Arts-Medicine Program at Boston University School of Medicine, graduating with an AB-MD degree in 1971, and completed a residency in Internal Medicine and a residency in Neurology at Boston City Hospital, now Boston Medical Center. He was trained in Medicine under Norman Levinsky and in Neurology under Norman Geschwind. He has published numerous scientific articles and books in the field of cognitive neurology, with a focus on learning disabilities and attention disorders, especially in adults.
Samuel J. Lin is an associate professor of surgery at Harvard Medical School and a plastic surgeon at Beth Israel Deaconess Medical Center. He is also the program director for the BIDMC/Harvard Plastic Surgery Residency Training Program and Co-Fellowship Director for the Aesthetic and Reconstructive Fellowship Program.
Susan Redline is an American pulmonary specialist. She is the Peter C. Farrell Professor of Sleep Medicine and Professor of Epidemiology at the Harvard T.H. Chan School of Public Health.
Kathryn T. Hall is a leader in public health, professor of medicine and molecular biologist who directs research or teaches at several institutions, including the following: