Tirap

Last updated March 07, 2019

Tirap can refer to:

Tirap district, district in Arunachal Pradesh
Tirap River, river that flows in Tirap district
Tirap, Kenya
TIRAP, toll-interleukin 1 receptor domain containing adaptor protein

The Tirap district (Pron:/tɪˈɹæp/) is located in the southeastern part of the state of Arunachal Pradesh in India. It shares a state border with Nagaland and Assam, an international border with Myanmar and a district border with Changlang and Longding.

Tirap is a river in Arunachal Pradesh in India.

TIRAP is an adapter molecule associated with toll-like receptors. The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described.

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Longding district (Pron:/lɒŋˈdɪŋ/) is one of the 20 administrative districts of Arunachal Pradesh in northeastern India. It was carved out of the south-western portion of the Tirap District. The district shares its boundary to the south and south-east with the country of Myanmar. Its boundary to the west and the north are shared with the Indian states of Nagaland and Assam, respectively. Towards the north-east is the Tirap District from which the district was carved out in 2012. The district has a population of around 60000 and an area of roughly 1200 square kilometers. Longding has pleasant climate throughout the year. Due to its hilly terrain, the temperature ranges from 15C to 30C in summers).

Yumsem Matey is a politician from Lazu Village, Tirap Dist. Arunachal Pradesh, state in India. He is member of Arunachal Pradesh Assembly from Khonsa West in Tirap district. He belong to Indian National congress. First Graduate from OLLO Community, in the year 1992-93, from Government College, Itanagar, Arunachal Pradesh. Served as District Adult Education Officer (DAEO) in Changlang, Changlang District, Arunachal Pradesh.

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