| Tlapalizquixochtzin | |
|---|---|
| Queen regnant of Ecatepec | |
| Reign | c. early 16th century | 
| Empress consort of the Aztec Empire Queen consort of Tenochtitlan | |
| Tenure | c. early 16th century | 
| Co-consort | Teotlalco | 
| Spouse | Moctezuma II | 
| Issue | Francisca de Moctezuma | 
| Father | Matlaccoatzin | 
Tlapalizquixochtzin was an Aztec noblewoman and Queen regnant of the Aztec city of Ecatepec. She was also a consort of Moctezuma II. [1] [2]
 
 She was born as a Princess – daughter of Matlaccoatzin and thus a granddaughter of the King Chimalpilli I and sister of Princess Tlacuilolxochtzin. [2]
Tlapalizquixochtzin married Aztec emperor Moctezuma II (c. 1466 – June 1520). Their daughter was Doña Francisca de Moctezuma. [2]
Her nephew was King Diego de Alvarado Huanitzin. [3]