UPK3B (gene)

Last updated
LOC105375355
Identifiers
Aliases LOC105375355
External IDs OMIM: 611887 GeneCards: LOC105375355
Orthologs
SpeciesHumanMouse
Entrez

105375355

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Ensembl

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UniProt

Q9BT76

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RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

NP_001334613
NP_085047
NP_872624
NP_872625

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Location (UCSC)n/an/a
PubMed search [1] n/a
Wikidata
View/Edit Human

Uroplakin 3B is a protein that in humans is encoded by the UPK3B gene. [2]

Protein Biological molecule consisting of chains of amino acid residues

Proteins are large biomolecules, or macromolecules, consisting of one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific three-dimensional structure that determines its activity.

Gene Basic physical and functional unit of heredity

In biology, a gene is a sequence of nucleotides in DNA or RNA that encodes the synthesis of a gene product, either RNA or protein.

Contents

Function

UPK3B is a minor component of the apical plaques of mammalian urothelium that binds and dimerizes with uroplakin-1b (UPK1B; MIM 602380), one of the major conserved urothelium membrane proteins.

UPK1B protein-coding gene in the species Homo sapiens

Uroplakin 1B, also known as UPK1B, is a protein which in humans is encoded by the UPK1B gene.

The other major conserved integral membrane proteins of urothelial plaques are UPK1A (MIM 611557), UPK2 (MIM 611558), and UPK3A (MIM 611559) (Deng et al., 2002 [PubMed 12446744]).[supplied by OMIM, Mar 2008].

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Uroplakin-2 is a protein that in humans is encoded by the UPK2 gene.

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Uroplakin-3a is a protein that in humans is encoded by the UPK3A gene.

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References

  1. ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  2. ↑ "Entrez Gene: Uroplakin 3B" . Retrieved 2018-05-09.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

United States National Library of Medicine Worlds largest medical library

The United States National Library of Medicine (NLM), operated by the United States federal government, is the world's largest medical library.

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