Unifying Systems in Catalysis

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The Cluster of Excellence Unifying Systems in Catalysis (UniSysCat) is an interdisciplinary research network funded by the German Research Foundation (DFG) as a part of the federal and state excellence strategy of Germany, Exzellenzstrategie. [1] [2] The funding period runs from January 1, 2019 to December 31, 2025. Around 300 researchers from the Berlin and Potsdam areas work at UniSysCat, focusing on current issues in catalysis research. [3] UniSysCat is the follow-up project of the Cluster of Excellence Unifying Concepts in Catalysis (UniCat), which was funded from 2007 to 2018 as part of the federal and state excellence initiative of Germany Exzellenzstrategie. [4]

Contents

Objectives

The primary objective of UniSysCat is to explore sustainable coupled catalytic reactions. Biocatalysts, mostly enzymes, enable biochemical and physiological processes in living beings. Researchers at UniSysCat study the complex, coupled processes that are driven by biocatalysts to recreate similar catalytic reaction networks in the laboratory. Biocatalysts, mostly enzymes, enable biochemical and physiological processes in living beings. Researchers at UniSysCat study the complex, coupled processes that are driven by biocatalysts to recreate similar catalytic reaction networks in the laboratory. These catalytic reaction networks should be controllable and used in a targeted manner in order to pave the way to sustainable chemistry based on the example of nature according to the principles of "green chemistry." [5] [6] [7]

Consortium

Spokespersons: Holger Dobbek (HU Berlin), Matthias Driess (TU Berlin), Arne Thomas (TU Berlin)

Research

UniSysCat consists of around 60 research groups with expertise in experimental methods and theoretical approaches in the fields of molecular and structural biology, biochemistry and biophysics, chemical synthesis, physical and theoretical chemistry and physics. UniSysCat's research strategy is based on the previous work of the UniCat Cluster of Excellence (Unifying Concepts in Catalysis). [3]

UniSysCat aims to decipher reaction networks in chemical and biological catalysis so that they can be controlled and simulated. Research is performed with a focus on parameters that enable and control chemocatalytic and biocatalytic networks and how chemical and biological processes can be coupled to create catalytic systems with new functions. [8]

Clara Immerwahr Award

The Clara Immerwahr Award, launched in 2011 by the UniCat Cluster of Excellence, is an award to promote outstanding young women in catalysis research. The award is given annually to a young scientist from Germany or abroad in an early phase of her career (postdoc, young scientist) for excellent performance in catalysis research. It is associated with a financial grant of 15,000 euros for a research stay in a UniSysCat research group and is intended to establish close cooperation with UniSysCat working groups. [9]

The Clara Immerwahr Award is dedicated to Dr. Clara Immerwahr (1870-1915), who was the first woman in Germany to receive a doctorate in physical chemistry in 1900. [10]

PhD Program (EC2/BIG-NSE)

A structural goal of UniSysCat is the sustainable promotion of young scientists. UniSysCat supports the so-called "EC2/BIG-NSE" doctoral program.

The term EC2/BIG-NSE is made up of the terms EC² (Einstein Center of Catalysis) and BIG-NSE (Berlin International Graduate School of Natural Sciences and Engineering). BIG-NSE was an international PhD program that was founded on May 29, 2007 at the Technical University Berlin, and was part of the Cluster of Excellence UniCat. [11] [12] Since January 1st, 2019, the BIG-NSE doctoral program has been financed by the "Einstein Center of Catalysis" sponsored by the Einstein Foundation Berlin, prompting the renaming of the program to EC2/BIG-NSE. The mission of this doctoral program is to overcome the limits of classical disciplines in catalysis. [13]

Knowledge Transfer

Catalysis research also plays an important role in industry, especially for sustainable chemistry. Various projects have been established to transfer the research results of UniSysCat to industrial applications.

BasCat

In 2011, the UniCat Cluster of Excellence and the chemical company BASF founded the joint laboratory, BasCat (UniCat BASF JointLab), at the Technical University of Berlin. BasCat is dedicated to basic research in the field of heterogeneous catalysis. The basic research should then also be transferred to industrial applications. [14]

Chemical Invention Factory

The Chemical Invention Factory (CIF, John Warner Center for Start-ups in Green Chemistry) is a project initiated at the TU Berlin that aims to encourage young scientists to become founders of their own start-ups. The Chemical Invention Factory supports research in the fields of green chemistry, materials, and nanotechnology. Plans for a new building include the presence of state-of-the-art laboratories in which young scientists, accompanied by mentors, can research their own ideas with the aim of developing their results in a start-up until they are ready for the market. [15]

INKULAB

The INKULAB was a project to promote young entrepreneurs in chemistry. The INKULAB project ended in April 2020 after five years of work. During these five years, eight junior teams had the opportunity to work in the laboratories while they were supported by the Center for Entrepreneurship at the Technical University of Berlin. [16]

Related Research Articles

<span class="mw-page-title-main">Catalysis</span> Process of increasing the rate of a chemical reaction

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Reductive amination is a form of amination that involves the conversion of a carbonyl group to an amine via an intermediate imine. The carbonyl group is most commonly a ketone or an aldehyde. It is a common method to make amines and is widely used in green chemistry since it can be done catalytically in one-pot under mild conditions. In biochemistry, dehydrogenase enzymes use reductive amination to produce the amino acid, glutamate. Additionally, there is ongoing research on alternative synthesis mechanisms with various metal catalysts which allow the reaction to be less energy taxing, and require milder reaction conditions. Investigation into biocatalysts, such as imine reductases, have allowed for higher selectivity in the reduction of chiral amines which is an important factor in pharmaceutical synthesis.

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The Berlin Graduate School of Natural Sciences and Engineering (BIG-NSE) is part of the Cluster of Excellence "Unifying Concepts in Catalysis" (UniCat) founded in November 2007 by the Technical University of Berlin and five further institutions in the Berlin area within the framework of the German government‘s Excellence Initiative.

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<span class="mw-page-title-main">Matthias Kraume</span> German chemical and process engineer

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References

  1. "DFG - GEPRIS - Unifying Systems in Catalysis "UniSysCat"". gepris.dfg.de.
  2. Burchard, Amory (September 27, 2018). "Sieben von neun Clusteranträgen bewilligt". Der Tagesspiegel Online via Tagesspiegel.
  3. 1 2 "UniSysCat: UniSysCat at a glance". www.unisyscat.de.
  4. "Exzellenzinitiative des Bundes und der Länder (2005-2017/2019)".
  5. "12 Principles of Green Chemistry".
  6. "Der Pflanzenzelle abgeschaut". Der Tagesspiegel Online. October 5, 2019 via Tagesspiegel.
  7. "Auf der Suche nach Heiratsvermittlern". Der Tagesspiegel Online. February 18, 2019 via Tagesspiegel.
  8. "Unifying Systems in Catalysis (UniSysCat)". www.berlin-university-alliance.de. September 26, 2017.
  9. "UniSysCat: Clara Immerwahr Award". www.unisyscat.de.
  10. "Clara Immerwahr | Gesellschaft Deutscher Chemiker e.V."
  11. "About us".
  12. "Unifying Concepts in Catalysis: Organization". www.unicat.tu-berlin.de.
  13. "UniSysCat: Early Career". www.unisyscat.de.
  14. "BasCat - UniCat BASF JointLab: BasCat". www.bascat.tu-berlin.de.
  15. ldaniel.eu, L. Daniel Swakman. "Chemical Invention Factory". Chemical Invention Factory.
  16. "INKULAB". www.inkulab.de.