Vaxess Technologies

Last updated
Vaxess Technologies Incorporated
FoundedDecember 18, 2011 (2011-12-18)
Headquarters,
Number of employees
42
Website Vaxess.com

Vaxess Technologies, Inc. is a company started by a team of four graduate students from Harvard developing a suite of vaccines on the MIMIX sustained dermal delivery platform that combines high temperature stability, improved efficacy, and simplified delivery to improve global vaccine access. [1] [2] [3] [4]

Contents

History

Students Michael Schrader, Livio Valenti, Kathryn Kosuda, and Patrick Ho started Vaxess in December 2011, based on a technology created by David Kaplan and Fiorenzo Omenetto. [5] [6] [7] Schrader graduated with an MBA from Harvard Business School in 2012. Valenti attended the John F. Kennedy School of Government. Kosuda had been a Harvard postdoctoral fellow in chemistry, and Patrick Ho had earned a J.D in 2012. [8]

In 2012, Vaxess was awarded $25,000 from Harvard Business School for Harvard's Business Plan Contest in the Business Ventures Track. [9] [10] [5] [11] Vaxess Technologies was a semi-finalist for MIT's $100K Entrepreneurship Competition in the Life Sciences section. [12] [13] In 2012, it won the Harvard President's Challenge in the Global Health section and was awarded $70,000. [14] [15] [16] [17] The company was selected as a finalist for two 2013 MassTLC Awards, Start-Up to Watch and Innovative Technology of the Year: Healthcare/Life Sciences. [18]

In May 2013, Vaxess received $3.75M in funding from Norwich Ventures and an undisclosed amount of money from angel investor Jeffrey Walker. [19]

In August 2013, the company announced that it would be moving out of Harvard's Innovation Lab to a new location at LabCentral in Cambridge. [20] [21]

In December 2013, the Massachusetts Life Sciences Center awarded $1.5M to local startups. Vaxess received $1M of that amount which is the most that the MLSC's Accelerator Loan Program will lend to one organization. Vaxess's CEO Michael Schrader was quoted as saying, "The $1 million Accelerator loan will enable Vaxess to grow the company’s internal R&D capabilities and deliver heat-stable vaccines to patients around the world even sooner." [22]

In January 2014, co-founder Livio Valenti was named by Forbes's 30 Under 30 in Science & Healthcare for his work with Vaxess. [23] [24] [25]

In February 2014, Vaxess added George Siber, M.D. to their organization as the chair of their Scientific Advisory Board. Previously, Siber served as the EVP and CSO of Wyeth Vaccines. He also played a role in bringing Prevnar to market. [26]

In April 2014, Vaxess announced that Thomas Monath, MD, and Russell Middaugh, PhD. would join the company's scientific advisory board. Monath being an expert in the field of vaccinology and Middaugh being an expert in the fields of in the fields of biophysical chemistry and pharmaceutical formulation. [27]

In February 2015, Verizon announced that Vaxess had won one of the $1M Verizon Powerful Answers Awards. Verizon issued approximately $6 million is prizes to 12 different organizations across 4 categories. Vaxess won first place in the Transportation category, above HopOn and Matternet. [28] [29]

In March 2017, Vaxess announced the receipt of $6M in grants from The Bill and Melinda Gates Foundation to advance both an inactivated polio vaccine as well as a measles-rubella vaccine on the company's MIMIX platform. The grants will fund development of both the MIMIX platform as well as these two specific indications over the next two years. [30]

In November 2022, Vaxess announced $27 million in Series B funding. [31] [32] In December 2022, the company announced initial phase 1 clinical trial results for its flu vaccine patch. [33]

Technology

Vaxess's business plan is based around a technology developed by Tufts University Professors Fiorenzo Omenetto and David Kaplan. The technology uses a silk-derived protein called fibroin to stabilize vaccines so that they can be shipped and stored without refrigeration, eliminating the need for the cold chain. [34] [35] [36] Vaxess is working with vaccine manufacturers to develop heat-stable vaccines and targeting a product launch by 2019. [37]

Related Research Articles

<span class="mw-page-title-main">Robert S. Langer</span> American scientist

Robert Samuel Langer Jr. FREng is an American biotechnologist, businessman, chemical engineer, chemist, and inventor. He is one of the nine Institute Professors at the Massachusetts Institute of Technology.

Andrew McCollum is an American angel investor and businessman. He is a co-founder of Facebook and the current chief executive officer of Philo.

<span class="mw-page-title-main">Where.com</span> Former American media company

Where, Inc. was a location-based media company in North America. Their main products were the WHERE consumer application and WHERE Ads, a hyper-local ad network that connected merchants with local audiences. PayPal announced its acquisition of Where, Inc. in 2011 for $135 million.

Clover Food Lab is a vegetarian fast food chain, founded in 2008 which operates food trucks and restaurants in Massachusetts, United States. The company serves a simple menu that changes daily and with the seasons based on what is available from local farmers and includes a large mix of organic ingredients. The company also offers meal delivery boxes and catering.

BostInno is a local online news site and community publishing platform covering "the view from inside" innovation in Boston. It was founded in 2008 as a community startup blog by Chase Garbarino, CEO and co-founder of Streetwise Media, and Kevin McCarthy, CTO and co-founder. On December 7, 2009, BostInno was relaunched as a news platform profiling local innovation across verticals including tech, venture capital, city news, food, higher education, and sports.

<span class="mw-page-title-main">CoachUp</span> American sports coaching company

CoachUp is a venture-funded startup company that connects athletes with private coaches.

<span class="mw-page-title-main">Kelvin Doe</span> African engineer

Kelvin Doe, also known as DJ Focus, is a Sierra Leonean engineer.

BlueJeans by Verizon was a company that provided an interoperable cloud-based video conferencing service. It was headquartered in the Santana Row district of San Jose, California. Prior to being acquired by Verizon in 2020, the company was known as "BlueJeans Network" Verizon decided to close down the Blue Jeans platform in August 2023, and closed the website in March 2024.

Harvard Innovation Labs (i-Lab) is an institution which aims to promote team-based and entrepreneurial activities among Harvard students, faculty, entrepreneurs, and members of the Allston and Greater Boston communities.

<span class="mw-page-title-main">DASHED</span> Food delivery service

Dashed, Inc. was a US restaurant delivery service founded in Boston, Massachusetts by Phil Dumontet in 2009. The company provided rapid delivery for over 800 restaurants that don't have their own services in Baltimore, Boston, Hoboken, New Haven, Philadelphia, Providence and Washington, DC.

<span class="mw-page-title-main">Boundless (company)</span>

Boundless was an American company, founded in 2011, which created free and low-cost textbooks and distributed them online. In April 2015, it was acquired by Valore. The combined company is based in Boston, Massachusetts.

Lab Central, Inc., also known as LabCentral, is a non-profit organization started in November 2013. Operating over 225,000 sq. feet in Cambridge and on the Harvard University campus, LabCentral offers a network of fully permitted laboratory and office spaces for as many as 125 biotech start-ups comprising approximately 1000 scientists and entrepreneurs in the heart of Kendall Square. Additionally, LabCentral is committed to creating a more sustainable and inclusive biotech system supporting developments in STEM, workforce training, and next generation entrepreneurship through its LabCentral Ignite initiative. LabCentral is also home to Gallery 1832 which engages the local community to celebrate artistic innovation.

<span class="mw-page-title-main">George Siber</span> Medical researcher and vaccine expert

George Rainer Siber is a medical researcher and vaccine expert with 49 years of experience in developing numerous vaccines, therapeutic antibodies, and diagnostic agents for infectious diseases.

<span class="mw-page-title-main">Antonio Rodriguez (entrepreneur)</span>

Antonio Rodriguez is a serial entrepreneur and venture capitalist.

<span class="mw-page-title-main">Jonathan Lacoste</span> American internet entrepreneur (born 1993)

Jonathan Lacoste is a venture capitalist and software entrepreneur based in Austin, TX. He is the Founder & General Partner at Space.VC, an early-stage venture capital fund specialized on space, defense, and frontier tech investments. Notable investments have included SpaceX, True Anomaly, and Loft Orbital. Previously, Jonathan was the Co-Founder of Jebbit, an enterprise software company he co-founded in 2011 with university classmates. He and co-founder Tom Coburn ran the company for 12 years before being acquired by Vista Equity Partners.

<span class="mw-page-title-main">Hugo Van Vuuren</span> South African American entrepreneur and investor (born 1984)

Hugo Van Vuuren is a South African American entrepreneur and investor. An expert-in-residence at the Harvard School of Engineering and Applied Sciences, he is the co-founder of Work-Bench, an early stage enterprise technology venture fund.

<i>Geeks & Greeks</i>

Geeks & Greeks is a semi-autobiographical graphic novel written by humorist Steve Altes, illustrated by Andy Fish, and colored by Veronica Fish. It includes a foreword by novelist Matthew Pearl and is dedicated to Sean Collier. Geeks & Greeks is set at the Massachusetts Institute of Technology and locations in Boston, Cambridge, and the Quincy Quarries. The story was inspired by MIT's hacking culture and the writer's experiences with fraternity hazing. At MIT a hack is a clever, benign prank or unsanctioned public display or installation that requires technical sophistication to execute and often incorporates an offbeat sense of humor. Geeks & Greeks has been described as Good Will Hunting meets Animal House.

<span class="mw-page-title-main">Philo (company)</span> American internet television company

Philo is an American internet television company based in San Francisco, California. First founded at Harvard University in 2010 by Tuan Ho and Nicholas Krasney, investors in the company include HBO, Andrew McCollum, and Mark Cuban. The company and its service is named in honor of one of the pioneering engineers of television, Philo T. Farnsworth. As of 2021, their OTT streaming television service has over 800,000 subscribers.

<span class="mw-page-title-main">HackMIT</span>

HackMIT is an annual student-run hackathon held in the fall at the Massachusetts Institute of Technology.

<span class="mw-page-title-main">Owl Labs</span>

Owl Labs is a company that makes 360° video conferencing devices called the "Meeting Owl", the "Meeting Owl Pro" and the "Meeting Owl 3." It was founded in 2014 by robotics experts Max Makeev and Mark Schnittman. It raised a total of $7.3M in venture capital from seed and Series A rounds led by serial entrepreneur Andy Rubin, Antonio Rodriguez and iRobot Ventures. In June 2017, it announced its Meeting Owl device. VentureBeat noted that unlike others Meeting Owl has "...a single 360-degree camera that can recognize and highlight the person speaking..." The device contains a Qualcomm Snapdragon.

References

  1. Burgstone, Jon (2012-04-25). "4 Harvard Start-ups to Watch". Inc.com. Retrieved 18 May 2012.
  2. "MIT $100K - Vaxess Technologies". Massachusetts Institute of Technology. Archived from the original on 12 May 2012. Retrieved 7 May 2012.
  3. Parrish, Kelsey (2014-02-25). "Vaxess Technologies – Michael A. Schrader Interview". Outlier Magazine. Retrieved 9 April 2014.
  4. Schiller, Ben (2017-03-14). "Designing a More Efficient, Temperature Proof Vaccine". FastCompany.com. Retrieved 5 May 2017.
  5. 1 2 Landry, Lauren (2012-04-25). "Harvard Business School's Business Plan Contest Doles Out Over $150K". BostInno. Retrieved 18 May 2012.
  6. "Vaxess History". Vaxess Technologies. Retrieved 18 May 2012.
  7. Landry, Lauren (2012-05-30). "How a Diverse Mix of Harvard Students & Tufts' Technology Can Increase the World's Vaccine Access". BostInno . Retrieved 31 May 2012.
  8. "Harvard entrepreneurs weave silk with science". Harvard Gazette, June 4, 2012
  9. "Harvard's Next Zuckerberg?". CNBC . 2012-05-18. Archived from the original on 2013-01-04. Retrieved 22 May 2012.
  10. Di Meglio, Francesca (2012-05-04). "B-School Highlights: May 4". Bloomberg . Archived from the original on May 10, 2012. Retrieved 18 May 2012.
  11. "Harvard Business School Holds 16th Annual Business Plan Contest". Harvard Business School . 2012-04-25. Retrieved 18 May 2012.
  12. Landry, Lauren (2012-04-19). "The 30 Semi-Finalist Teams Competing in MIT $100K's Life Science, Product & Emerging Market Tracks". BostInno. Retrieved 18 May 2012.
  13. "MIT$100K Semi Finalists". MIT . Retrieved 18 May 2012.
  14. Friedman, Amy (2012-06-05). "Vaccination Company Wins President's Challenge Grand Prize". The Harvard Crimson . Retrieved 6 June 2012.
  15. "President's Challenge Finalist Teams". Harvard . Retrieved 18 May 2012.
  16. Landry, Lauren (2012-04-12). "Harvard's Innovation Lab Announces the 10 Teams Competing for $100K in the President's Challenge". BostInno. Retrieved 18 May 2012.
  17. Moore, Mary (2012-06-04). "Startup Vaxess Technologies wins Harvard social enterprise award". Boston Business Journal . Retrieved 4 June 2012.
  18. "MassTLC Technology Leadership Awards: 2013 Finalists Archived 2013-09-26 at the Wayback Machine ". MassTLC. Retrieved 15 August 2013
  19. Lauren, Landry (2013-05-23). "Aimed at Increasing Vaccine Access, Vaxess Raises the First Part of a $3.75M Series A". BostInno. Retrieved 14 August 2013.
  20. "Twitter Moves to LabCentral". Twitter. Retrieved 13 August 2013.
  21. Fruehauf, Johannes. "First company selected for LabCentral: Vaxess". LabCentral. Archived from the original on 30 December 2013. Retrieved 14 August 2013.
  22. Borchers, Callum (2013-12-19). "Massachusetts Life Sciences Center awards $1.5 million in new loans". Boston Globe . Retrieved 19 December 2013.
  23. "2014 30 Under 30: Science & Healthcare". Forbes . Archived from the original on January 9, 2014. Retrieved 28 January 2014.
  24. Fumagalli, Laura (2014-01-27). "Livio: dalla Bocconi a Forbes, pensando alla Cambogia". Sarfatti, 25. Retrieved 28 January 2014.
  25. Benedettelli, Benedettelli (2014-07-05). "I vaccini senza frigorifero di due italiani ad Harvard". Avvenire. Retrieved 8 July 2014.
  26. "Vaccine Industry Leader George Siber, M.d. Joins Vaxess Technologies As Chairman Of Scientific Advisory Board" (PDF). Vaxess. Archived from the original (PDF) on 23 February 2014. Retrieved 4 February 2014.
  27. "Thomas Monath and Russell Middaugh Join Scientific Advisory Board of Vaxess Technologies". FierceMarkets . 2014-04-04. Archived from the original on April 6, 2014. Retrieved 5 April 2014.{{cite news}}: CS1 maint: unfit URL (link)
  28. "Verizon's $1M Powerful Answers Award Winners Boast Solutions with Potential to Change our World for the Better". PR Newswire. 2015-01-03. Retrieved 22 March 2015.
  29. Paul, Joseph (2015-02-15). "Purdue graduate's technology could help stabilize vaccines". Daily Herald. Retrieved 22 March 2015.
  30. "Vaxess Technologies Receives Grants Totaling $6 Million to Develop Microneedle Vaccines for Polio, Measles, Rubella". PR Newswire. 2017-03-06.
  31. Cross, Ryan (November 2, 2022). "Hate needles? Flu vaccines of the future could be skin patches delivered to your door. - The Boston Globe". BostonGlobe.com. Retrieved 2023-01-06.
  32. FinSMEs (2022-11-03). "Vaxess Raises $27M in Series B Funding". FinSMEs. Retrieved 2023-01-06.
  33. Taylor, Nick Paul (2022-12-20). "Vaxess' flu vaccine patch passes early clinical test, clearing path for further development". Fierce Pharma. Retrieved 2023-01-06.
  34. "Vaxess Technologies". Harvard Innovation Lab . Retrieved 20 May 2012.
  35. Marinelli, Andrea (2012-06-13). "Vaxess, la startup italiana che ha conquistato Harvard". America24. Retrieved 14 June 2012.
  36. "Winning the competition for ideas". Boston Globe . 2012-05-20. Retrieved 21 May 2012.[ dead link ]
  37. Cohan, Peter (2012-08-13). "Vaxess Goes To Harvard". Forbes . Retrieved 13 August 2012.