Warren C. Breidenbach

Last updated

Warren C. Breidenbach III (born California) is an American hand surgeon most well known for having performed the first long-term successful hand transplant surgery in the world at Jewish Hospital in Louisville, Kentucky. [1] The surgery was performed by Breidenbach and hand surgeon Tsu-Min Tsai, both of Kleinert, Kutz and Associates Hand Care Center, leading a team of surgeons to attach a donor left hand to replace New Jersey native Matthew Scott's left hand. The Louisville hand surgery team went on to perform additional hand transplants between 1999 and 2011, when Breidenbach relocated to the University of Arizona in Tucson, Arizona to start a Composite Tissue Allotransplantation center at the university's medical center. [2]

Breidenbach attributes the team's success in the first hand transplant to feasibility studies and research, including reviews of the medical literature, prior to the clinical procedure. [3]

Breidenbach graduated from the University of Calgary.

Related Research Articles

<span class="mw-page-title-main">William DeVries</span> American physician

William Castle DeVries is an American cardiothoracic surgeon, mainly known for the first transplant of a TAH using the Jarvik-7 model.

<span class="mw-page-title-main">Organ transplantation</span> Medical procedure in which an organ is removed from one body and placed in the body of a recipient

Organ transplantation is a medical procedure in which an organ is removed from one body and placed in the body of a recipient, to replace a damaged or missing organ. The donor and recipient may be at the same location, or organs may be transported from a donor site to another location. Organs and/or tissues that are transplanted within the same person's body are called autografts. Transplants that are recently performed between two subjects of the same species are called allografts. Allografts can either be from a living or cadaveric source.

Allotransplant is the transplantation of cells, tissues, or organs to a recipient from a genetically non-identical donor of the same species. The transplant is called an allograft, allogeneic transplant, or homograft. Most human tissue and organ transplants are allografts.

Hand transplantation, or simply hand transplant, is a surgical procedure to transplant a hand from one human to another. The donor hand, usually from a brain-dead donor, is transplanted to a recipient amputee. Most hand transplants to date have been performed on below-elbow amputees, although above-elbow transplants are gaining popularity. Hand transplants were the first of a new category of transplants where multiple organs are transplanted as a single functional unit, now termed vascularized composite allotransplantation or VCA.

<span class="mw-page-title-main">Face transplant</span> Medical procedure to replace a persons face using donor tissue

A face transplant is a medical procedure to replace all or part of a person's face using tissue from a donor. Part of a field called "Vascularized Composite Tissue Allotransplantation" (VCA) it involves the transplantation of facial skin, the nasal structure, the nose, the lips, the muscles of facial movement used for expression, the nerves that provide sensation, and, potentially, the bones that support the face. The recipient of a face transplant will take life-long medications to suppress the immune system and fight off rejection.

<span class="mw-page-title-main">Microsurgery</span>

Microsurgery is a general term for surgery requiring an operating microscope. The most obvious developments have been procedures developed to allow anastomosis of successively smaller blood vessels and nerves which have allowed transfer of tissue from one part of the body to another and re-attachment of severed parts. Microsurgical techniques are utilized by several specialties today, such as general surgery, ophthalmology, orthopedic surgery, gynecological surgery, otolaryngology, neurosurgery, oral and maxillofacial surgery, plastic surgery, podiatric surgery and pediatric surgery.

Peter Edward Michael Butler, FRCSI, FRCS, FRCS (Plast) is Professor of Plastic and Reconstructive Surgery at University College London. He is consultant plastic surgeon and head of the face transplantation team at the Royal Free London NHS Foundation Trust in London, United Kingdom. He is Director of the Charles Wolfson Center for Reconstructive Surgery at the Royal Free Hospital, which was launched in November by The Right Honourable George Osborne, MP, Chancellor of the Exchequer at No 11 Downing Street in November 2013.

Penis transplantation is a surgical transplant procedure in which a penis is transplanted to a patient. The penis may be an allograft from a human donor, or it may be grown artificially, though the latter has not yet been transplanted onto a human.

Maria Siemionow is a Polish transplant surgeon and scientist. She is known for leading a team of eight surgeons through the first near-total face transplant performed in the United States at the Cleveland Clinic in 2008. The patient, Connie Culp, a 45-year-old woman from a small town in Ohio, was exceedingly disfigured by a close range shotgun blast in 2004. The procedure took 22 hours.

<span class="mw-page-title-main">Heart transplantation</span> Surgical transplant procedure

A heart transplant, or a cardiac transplant, is a surgical transplant procedure performed on patients with end-stage heart failure or severe coronary artery disease when other medical or surgical treatments have failed. As of 2018, the most common procedure is to take a functioning heart, with or without both lungs, from a recently deceased organ donor and implant it into the patient. The patient's own heart is either removed and replaced with the donor heart or, much less commonly, the recipient's diseased heart is left in place to support the donor heart.

<span class="mw-page-title-main">Gunther O. Hofmann</span>

Gunther O. Hofmann is a German surgeon, biophysicist, and professor.

The University of Louisville School of Medicine at the University of Louisville is a medical school located in Louisville, Kentucky, United States. Opened as the Louisville Medical Institute in 1837, it is one of the oldest medical schools in North America and the 9th oldest in the United States.

Rainer W.G. Gruessner is a German-born American general surgeon and transplant surgeon, most noted as a surgical pioneer for his clinical and research innovations. Gruessner was the first transplant surgeon to perform all types of abdominal transplants from living donors.

<span class="mw-page-title-main">Robert C. Robbins</span> American cardiothoracic surgeon

Robert Clayton Robbins, known professionally as Robert C. Robbins or R.C. Robbins, is an American cardiothoracic surgeon and the 22nd and current president of The University of Arizona. Previously, he was the president and CEO of the Texas Medical Center in Houston, Texas, from 2012 to 2017. As an internationally recognized cardiac surgeon, he has focused his clinical efforts on acquired cardiac diseases, including surgical treatment of congestive heart failure and cardiothoracic transplantation. He also serves on the board of the Greater Phoenix Economic Council.

Ren Xiaoping is a Chinese orthopedic surgeon, and is most well-known for being part of the team that achieved the first hand transplant in China.

Wei-Ping Andrew Lee is a Taiwanese-American hand surgeon and medical researcher. He is presently the Dean of the University of Texas Southwestern Medical School and Executive Vice President for Academic Affairs and Provost of UT Southwestern Medical Center. Lee focuses on translational research on immune modulation for vascularized composite allotransplantation (VCA) and the implementation of protocols to minimize immunosuppression in hand transplant and other VCA programs.

Jack Greene Copeland is an American cardiothoracic surgeon, who has established procedures in heart transplantation including repeat heart transplantation, the implantation of total artificial hearts (TAH) to bridge the time to heart transplant, innovations in left ventricular assist devices (LVAD) and the technique of "piggybacking" a second heart in a person, while leaving them the original.

<span class="mw-page-title-main">Keith Reemtsma</span> American surgeon

Keith Reemtsma was an American transplant surgeon, best known for the cross-species kidney transplantation operation from chimpanzee to human in 1964. With only the early immunosuppressants and no long-term dialysis, the female recipient survived nine months, long enough to return to work.

<span class="mw-page-title-main">Eduardo D. Rodriguez</span> American physician

Eduardo De Jesus Rodriguez MD, DDS is a Cuban American plastic and reconstructive surgeon, and reconstructive transplant surgeon, who is known for his contribution to the field of facial transplantation and vascularized composite allotransplantation. Rodriguez practiced in Baltimore until 2013 when he was appointed the Helen L. Kimmel Professor of Reconstructive Plastic Surgery and Chair of the Hansjörg Wyss Department of Plastic Surgery at NYU Langone Health, where he serves as the director of the Face Transplant Program. Most recently, he led the team that performed the first simultaneous face and double hand transplantation, on August 12, 2020, on recipient Joe Dimeo, a 22-year-old man who suffered full-thickness burns to over 80% of his body after a high-speed car accident in 2018.

<span class="mw-page-title-main">Susan Mackinnon</span> Canadian surgeon (born c. 1950)

Susan Mackinnon is a Canadian plastic and reconstructive surgeon who is a pioneer in the field of peripheral nerve transfer and regeneration. She performed the world's first nerve allotransplantation in 1988. She is a past president of the American Association of Plastic Surgeons, the Plastic Surgery Research Council, and the American Association of Hand Surgery. As of 2022, she is the Minot Packer Fryer Professor of Plastic Surgery at Washington University School of Medicine in St. Louis, United States.

References

  1. Lawrence K., Altman (January 26, 1999). "Doctors in Louisville Perform Nation's First Hand Transplant". The New York Times. Retrieved 3 September 2012.
  2. "Warren C. Breidenbach III, MD, MSc biography". University of Arizona. Retrieved 3 September 2012.
  3. Shirbacheh, MV; Jones, JW; Breidenbach, WC; McCabe, SJ; Barker, JH; Gruber, SA (1998). "The case for local immunosuppressant in composite tissue allotransplantation". Transplantation Proceedings. 30 (6): 2739–42. doi:10.1016/s0041-1345(98)00800-8. PMID   9745558.