Yehuda Shoenfeld (born February 14, 1948)is an Israeli physician and autoimmunity researcher.
Israel, officially the State of Israel, is a country in Western Asia, located on the southeastern shore of the Mediterranean Sea and the northern shore of the Red Sea. It has land borders with Lebanon to the north, Syria to the northeast, Jordan on the east, the Palestinian territories of the West Bank and Gaza Strip to the east and west, respectively, and Egypt to the southwest. The country contains geographically diverse features within its relatively small area. Israel's economic and technological center is Tel Aviv, while its seat of government and proclaimed capital is Jerusalem, although the state's sovereignty over Jerusalem has only partial recognition.
A physician, medical practitioner, medical doctor, or simply doctor, is a professional who practises medicine, which is concerned with promoting, maintaining, or restoring health through the study, diagnosis, prognosis and treatment of disease, injury, and other physical and mental impairments. Physicians may focus their practice on certain disease categories, types of patients, and methods of treatment—known as specialities—or they may assume responsibility for the provision of continuing and comprehensive medical care to individuals, families, and communities—known as general practice. Medical practice properly requires both a detailed knowledge of the academic disciplines, such as anatomy and physiology, underlying diseases and their treatment—the science of medicine—and also a decent competence in its applied practice—the art or craft of medicine.
Autoimmunity is the system of immune responses of an organism against its own healthy cells and tissues. Any disease that results from such an aberrant immune response is termed an "autoimmune disease". Prominent examples include celiac disease, diabetes mellitus type 1, sarcoidosis, systemic lupus erythematosus (SLE), Sjögren's syndrome, eosinophilic granulomatosis with polyangiitis, Hashimoto's thyroiditis, Graves' disease, idiopathic thrombocytopenic purpura, Addison's disease, rheumatoid arthritis (RA), ankylosing spondylitis, polymyositis (PM), dermatomyositis (DM) and multiple sclerosis (MS). Autoimmune diseases are very often treated with steroids.
Yehuda Shoenfeld works at Sheba Medical Center in Tel HaShomer and the Sackler Faculty of Medicine at Tel-Aviv University. He studied at the Hebrew University of Jerusalem. He is the incumbent of the Laura Schwarz-Kipp Chair for Research of Autoimmune Diseases. Shoenfeld is the editor of two journals, Harefuah (Medicine) in Hebrew with English abstracts and Israel Medical Association Journal (IMAJ). He is co-editor-in-chief of Autoimmunity Reviews ,and co-editor of the Journal of Autoimmunity , and member of the editorial board of the Clinical Reviews in Allergy & Immunology.
The Chaim Sheba Medical Center at Tel HaShomer, also Tel HaShomer Hospital, is the largest hospital in Israel, located in the Tel HaShomer neighborhood of Ramat Gan, in the Tel Aviv District. In 2019, Newsweek ranked it as the 10th-best hospital in the world.
Tel HaShomer or Kiryat Krinitzi is a Neighborhood in Ramat Gan, Israel. It is bordered to the north by Kiryat Ono, to the east by Yehud, and to the south by Or Yehuda. A major Israel Defense Forces base and the Sheba Medical Center are located in Tel HaShomer.
Sackler Faculty of Medicine is a medical school affiliated with Tel Aviv University, located in Tel Aviv, Israel.
While two of Shoenfeld's scientific articles have been retracted,he has published more than 1920 papers. Also, he has authored and edited 40 books and contributed more than 350 chapters to various books, most recently Vaccines and Autoimmunity published by Wiley Blackwell. Prof. Shoenfeld is on the editorial board of 43 medical journals.
Shoenfeld received the EULAR Prize (Austria, 2005). He received the Nelson’s Prize for Humanity and Science from U.C. Davis (U.S., 2008). He was honored as Doctoris Honoris Causa by Debrecen University (Hungary, 2009). He has awarded a Life Contribution Prize in Internal Medicine (Israel, 2012), as well as the ACR Master Award (U.S., 2013). He is an honorary member of the Hungarian Association of Rheumatology, Slovenian National Academy of Sciences and the Royal Society of Physicians (UK).
Antinuclear antibodies are autoantibodies that bind to contents of the cell nucleus. In normal individuals, the immune system produces antibodies to foreign proteins (antigens) but not to human proteins (autoantigens). In some individuals, antibodies to human antigens are produced.
The Lancet is a weekly peer-reviewed general medical journal. It is among the world's oldest, most prestigious, and best known general medical journals.
Immunostimulants, also known as immunostimulators, are substances that stimulate the immune system by inducing activation or increasing activity of any of its components. One notable example is the granulocyte macrophage colony-stimulating factor.
Ruth Arnon is an Israeli biochemist and codeveloper of the multiple sclerosis drug Copaxone. She is currently the Paul Ehrlich Professor of Immunology at the Weizmann Institute of Science, where she is researching anti-cancer and influenza vaccinations.
An autoimmune disease is a condition arising from an abnormal immune response to a normal body part. There are at least 80 types of autoimmune diseases. Nearly any body part can be involved. Common symptoms include low grade fever and feeling tired. Often symptoms come and go.
Sir Marc Feldmann,, is an Australian immunologist, and a professor at the University of Oxford.
Michael D. Lockshin, M.D., is an American professor and medical researcher. He is a researcher of autoimmune diseases, with focus on antiphospholipid syndrome and lupus. He is currently Professor of Medicine and Obstetrics-Gynecology at the Weill-Cornell University Medical College in New York City. In addition, he is Director, Barbara Volcker Center for Women and Rheumatic Disease and Co-Director, Mary Kirkland Center for Lupus Research both at the Hospital for Special Surgery
Autoimmune polyendocrine syndrome type 1 (APS-1), also known as autoimmune polyendocrinopathy-candidiasis–ectodermal dystrophy/dysplasia (APECED), autoimmune polyglandular syndrome type 1, Whitaker syndrome, or candidiasis-hypoparathyroidism–Addison's disease syndrome, is a subtype of autoimmune polyendocrine syndrome in which multiple endocrine glands dysfunction as a result of autoimmunity. It is a genetic disorder inherited in autosomal recessive fashion due to a defect in the AIRE gene , which is located on chromosome 21 and normally confers immune tolerance.
Eliezer (Eli) Schwartz MD, DTMH is an Israeli physician, known for his speciality in tropical diseases and travel medicine. He is a founding member of the International Society of Travel Medicine (ISTM) and served as chair of its Professional Education Committee. Schwartz is currently president of the Asia Pacific Travel Health Society (APTHS) as well as the Israel Society for Parasitology, Protozoology and Tropical Diseases (ISPPTD). At clinical practice, he is head of the Center for Travel Medicine and Tropical Diseases at the Sheba Medical Center. He is also a Professor at the Sackler Faculty of Medicine, Tel Aviv University.
Autoimmunity is an international, peer-reviewed medical journal that covers the pathogenesis, immunology, genetics, and molecular biology of immune and autoimmune responses. In addition, the journal focuses on the autoimmune processes associated with systemic lupus erythematosus, rheumatoid arthritis, Sjögren syndrome, diabetes, multiple sclerosis, and other systemic and organ-specific autoimmune diseases.
Bonita Sue "Bonnie" Dunbar is a former professor in the department of molecular and cell biology at Baylor College of Medicine, a position she held from 1994 to 2004. Prior thereto she was an assistant professor in the same department at the same university from 1981 to 1983. From 1984 to 1994, also at Baylor College of Medicine, she also held a position as associate professor in the department of obstetrics and gynecology. She is currently an honorary lecturer at the University of Nairobi. She is a member of the American Association for the Advancement of Science, the Endocrine Society, the American Society for Cell Biology, and the New York Academy of Sciences. She is currently the owner of the Karen Blixen Coffee Garden Restaurant and Cottages, as well as the treasurer of the African Biomedical Center. She also served on the editorial board of the journal Medical Veritas, which was published from 2004 to 2008 and endorsed anti-vaccine views.
Autoimmune/inflammatory syndrome induced by adjuvants, also known as Shoenfeld's syndrome or ASIA, is a theoretical autoimmune disorder proposed by Israeli immunologist Yehuda Shoenfeld in 2011. According to Shoenfeld, the syndrome includes four conditions: "post-vaccination symptoms," macrophagic myofasciitis, Gulf war syndrome, sick building syndrome, and siliconosis. Shoenfeld alleges that the syndrome is caused by adjuvants such as silicone, tetramethylpentadecane, pristane, and aluminum. However, causality is difficult to prove because ASIA only occurs in a small fraction of patients exposed to these adjuvants. Additionally, proponents of this theory allege that the disorder can manifest anywhere from 2 days to 23 years after exposure. Shoenfeld has also named Sjögren's syndrome as potentially being another facet of ASIA. In 2013, the authors of a textbook on autoimmune diseases concluded that "there exists persuasive evidence for ASIA," but noted that several academic and governmental agencies had dismissed the possibility of a link between silicone and autoimmune disease.
Narinder Kumar Mehra is an Indian immunologist, head of the department of transplant immunology and immunogenetics of the SRL Limited, Gurgaon. He is a former dean of research and holds the ICMR Dr. C.G. Pandit National Chair at AIIMS. An elected fellow of the International Medical Sciences Academy, The World Academy of Sciences, Indian National Science Academy and National Academy of Sciences, India, Mehra is known for his research on histocompatibility and immunogenetics. The Council of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him the Shanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards for his contributions to Medical Sciences in 1992. He received the Chevalier of the National Order of Merit from François Mitterrand in 2003.
Christopher Ariel Shaw is a Canadian neuroscientist and professor of ophthalmology at the University of British Columbia (UBC).
Prof. Joshua Shemer chairs the Assuta Medical Centers network in Israel, currently building and developing the new advanced highly sophisticated public hospital in the city of Ashdod, the first of its kind built in Israel in the past forty years. He formerly served as Director General of Maccabi Healthcare Services, providing health services to 24% of the Israeli population. Shemer served as director general of the Ministry of Health and Surgeon General of the Israel Defense Forces Military Health Corps, holding the rank of brigadier general.
Autoimmunity Reviews is a bimonthly peer-reviewed medical journal publishing review articles pertaining to autoimmunity. It was established in 2002 and is published by Elsevier. The editors-in-chief are Yehuda Shoenfeld and M. Eric Gershwin. According to the Journal Citation Reports, the journal has a 2016 impact factor of 8.961.
Robert George Lahita is an American physician, internist and rheumatologist, best known for his research into systemic lupus erythematosus. and other autoimmune diseases. He is the author of more than 16 books and 150 scientific publications in the field of autoimmunity and immuno-endocrinology and a media consultant on health-related issues. He currently serves as Chairman of Medicine at St. Joseph's Healthcare System, specializing in rheumatology, and treatment of diseases of joints, muscle, bones and tendons including arthritis, back pain, muscle strains, common athletic injuries and collagen diseases.
Lars Klareskog is a Swedish physician, immunologist, and rheumatologist, known for research into the genetics of autoimmune diseases such as rheumatoid arthritis (RA).