Yissum Research Development Company of the Hebrew University

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Yissum Research Development Company (commonly referred to as Yissum) is the technology transfer company of the Hebrew University of Jerusalem. Established in 1964, Yissum is one of the world's third technology transfer organizations, facilitating the commercialization of innovative research and technologies developed by the university's researchers [1] .

Contents

Yissum connects researchers with industry leaders, entrepreneurs, and investors, enabling the transfer of academic knowledge to the marketplace. It has contributed to the establishment of numerous successful companies and the development of groundbreaking technologies across diverse fields, including biotechnology, agriculture, nanotechnology, and artificial intelligence.

History

Yissum was founded in 1964 [2] to bridge the gap between academic research and industry. Over the decades, the company has managed thousands of patents, technology licenses, and spin-off companies originating from research [3] conducted at the Hebrew University of Jerusalem.

Prominent technologies that originated from Yissum include the development of the Exelon drug [4] for Alzheimer's disease, Doxil for cancer treatment [5] , and agricultural innovations like seed breeding for improved crops [6] .

In January 2025, Alon Natanson was appointed as the Chief Executive Officer of Yissum, succeeding Dr. Itzik Goldwaser, who led the company for 15 years [7] . Natanson, an alumnus of the Hebrew University, brings extensive experience in transforming life sciences and technology companies, including roles at Nonagon Ltd., Apos Medical Assets, and Brainstorm Cell Therapeutics. [8]

Start-up companies

Yissum has played a pivotal role in founding numerous companies, including:

FuturaGene (2000) – Specializing in genetically enhanced trees for the forestry and biofuel industries [9] . CollPlant (2004) – Developing plant-based recombinant collagen for regenerative medicine [10] . BioBetter (2015) – Producing growth factors for cultivated meat using tobacco plants [11] . Melodea (2010) – Creating sustainable cellulose-based materials for packaging [12] .

Areas of Focus

Yissum's portfolio spans a wide range of industries, including:

Life Sciences and Biotechnology – Developing treatments for diseases, medical devices, and biotechnological applications. Agriculture and Food Technology – Innovations in crop improvement, food safety, and sustainable food production. Nanotechnology and Materials – Research on advanced materials and nanotechnological applications. Computer Science and Artificial Intelligence – Developing algorithms, machine learning models, and software technologies. Impact

As of 2025, Yissum has registered over 12,000 patents, licensed more than 3,000 technologies, and facilitated the creation of over 250 spin-off companies. Its work has generated substantial economic impact, with products and technologies originating from Yissum used worldwide [13] .

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References

  1. "Tech transfer, the secret behind Israel's innovation ecosystem - opinion". 3 March 2022.
  2. "About Us - Yissum". www.yissum.co.il. 2022-03-22. Retrieved 2025-01-13.
  3. "Something went wrong".
  4. "Israel's Exelon inventor sees an end to Alzheimer's". The Times of Israel .
  5. "Something went wrong".
  6. "Patents Assigned to YISSUM RESEARCH DEVELOPMENT COMPANY THE HEBREW UNIVERSITY OF JERUSALEM - Justia Patents Search".
  7. "The Blogs: Innovating through chaos and breaking barriers".
  8. "Alon Natanson Appointed as Chief Executive Officer of Yissum, Hebrew University's Tech Transfer Company".
  9. https://www.patentguru.com/assignee/yissum-research-development-company-of-the-hebrewuniversity-of-jerusale-m-ltd
  10. "Congratulations to Yissum Spin-out CollPlant for Raising $4.45M in the Capital! - JLM-BioCity". 9 March 2020.
  11. "BioBetter company information, funding & investors".
  12. https://www.businesswire.com/news/home/20130314005498/en/Yissum-Licenses-to-Melodea-a-Breakthrough-Technology-for-Manufacturing-Micro-Crystalline-Cellulose-Composite-Foams-from-Renewable-Resources
  13. https://plataformacti.cat/wp-content/uploads/2019/07/PPT_Gustavo-Fuchs_Yissum_Seminari-Internacional-2013.pdf