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Yu-Jui Yvonne Wan a biomedical scientist who has worked in three US medical centers.
Dr. Wan was raised in Taipei. She attended the grade school named the National Taipei University of Education Experimental Elementary School and was awarded as an Outstanding Alumnus of that School. She continued her studies in the Taipei Municipal Jinhua Junior High School, followed by attending the Taipei Municipal Zhong Shan Girls High School. She then received her Bachelor of Science with honors from Taipei Medical University, School of Pharmacy in 1979. Dr. Wan was elected as the Outstanding Alumnus of TMU due to her academic achievements. [1] After graduating from TMU, she continued to advance her education at Hahnemann University, now known as Drexel University. She received a Master of Science degree in two years and a Doctor of Philosophy degree from the same institution two years later.
Dr. Wan started her independent scientific career in 1989 as a faculty member in the Department of Pathology at the University of California, Los Angeles (UCLA). She established her laboratory at Harbor UCLA, where she studied the roles of retinoic acid and nuclear receptors in liver health and disease development, funded by the NIH. She also performed clinical research for longer than a decade to understand the drinking issues related to gene polymorphisms in ethnic minority populations funded by the NIH. She rose from assistant to associate and then full professor at UCLA before relocating to University of Kansas Medical Center. [2]
In 2003, Dr. Wan served as a Full Professor for the Department of Pharmacology, Toxicology and Therapeutics at the University of Kansas Medical Center in Kansas City, Kansas. [3] She was also heavily involved in other roles as the Leader of the Cancer Biology Program and the Founding Director of the Liver Center. She aided in obtaining multi-million-dollar NIH Centers of Biomedical Research Excellence (COBRE) funding, which benefited many liver researchers in the Mid-West, enabling junior faculty to start their research laboratories and programs.
In 2012, Dr. Wan relocated to the University of California, Davis in Sacramento, California, with her appointment as Professor and Vice Chair of Research in the Department of Pathology and Laboratory Medicine. [2] She became the 129th woman professor recruited to UC Davis. Her current research focus is the diet-gut-liver axis, which affects the development of metabolic dysfunction-associated steatohepatitis (MASH) and Hepatocellular carcinoma (HCC). She also studies the dietary effects via the gut microbiome influencing neuroplasticity and skin health, i.e., the diet-gut-brain or skin axis.
As the Vice Chair of Research for the Department of Pathology and Laboratory Medicine, she has contributed to increasing the department's research ranking at the national level by 25 positions since her induction as vice-chair in 2012.
In 2022, Dr. Wan was advanced to the University of California Distinguished Professor, the highest campus-level faculty title that can be bestowed. [4]
Dr. Wan has received many awards and honors for her dedication to science. A few examples are listed here. In 2003, she was recognized as a Distinguished Women in Research for years of dedicated service to advancing medical research, presented by California Congresswoman Jane Harman. Between 2007 and 2010, she received the Joy McCann Professorship in recognition of contributions to biomedical research and mentoring programs. [5] In 2009, she was recognized as the Women in Toxicology SIG Elsevier Mentoring Award from the Society of Toxicology for outstanding mentorship. [6] In 2010, she received the Chancellor's Club Research Award at the University of Kansas. [3] In 2019, Dr. Wan was awarded the Best Tea Health Advocate at the World Tea Expo for her lab's innovative work uncovering the beneficial effects of epigallocatechin-3-gallate present in tea. [7] In 2020, Dr. Wan was honored with the Dean's Award of Excellence from the University of California, Davis due in part to her lab's contribution to producing novel nano drugs for liver treatment and prevention. [8]
Dr. Wan has published over 224 peer-reviewed scientific publications, which can be found in https://www.ncbi.nlm.nih.gov/myncbi/yu-jui.wan.1/bibliography/public/
The University of California Davis School of Medicine is the medical school of the University of California, Davis. While the parent institution is located in Davis, California, the medical school is in Sacramento, California.
Taipei Medical University in Taiwan is located in Taipei's Xinyi District. Founded as Taipei Medical College in 1960, it was renamed as Taipei Medical University in 2000. TMU has expanded into a university with ten colleges, 6,000 students per year, five hospitals, and more than 40,000 alumni around the world.
UC Davis Medical Center (UCDMC) is part of UC Davis Health and a major academic health center located in Sacramento, California. It is owned and operated by the University of California as part of its University of California, Davis campus. The medical center sits on a 142-acre (57 ha) campus (often referred to as the Sacramento Campus to distinguish it from the main campus in nearby Davis) located between the Elmhurst, Tahoe Park, and Oak Park residential neighborhoods. The site incorporates the land and some of the buildings of the former Sacramento Medical Center (which was acquired from the County of Sacramento in 1973) as well as much of the land (and two buildings) previously occupied by the California State Fair until its 1967 move to a new location.
Harvey James Alter is an American medical researcher, virologist, physician and Nobel Prize laureate, who is best known for his work that led to the discovery of the hepatitis C virus. Alter is the former chief of the infectious disease section and the associate director for research of the Department of Transfusion Medicine at the Warren Grant Magnuson Clinical Center in the National Institutes of Health (NIH) in Bethesda, Maryland. In the mid-1970s, Alter and his research team demonstrated that most post-transfusion hepatitis cases were not due to hepatitis A or hepatitis B viruses. Working independently, Alter and Edward Tabor, a scientist at the U.S. Food and Drug Administration, proved through transmission studies in chimpanzees that a new form of hepatitis, initially called "non-A, non-B hepatitis" caused the infections, and that the causative agent was probably a virus. This work eventually led to the discovery of the hepatitis C virus in 1988, for which he shared the Nobel Prize in Physiology or Medicine in 2020 along with Michael Houghton and Charles M. Rice.
Liver cancer, also known as hepatic cancer, primary hepatic cancer, or primary hepatic malignancy, is cancer that starts in the liver. Liver cancer can be primary in which the cancer starts in the liver, or it can be liver metastasis, or secondary, in which the cancer spreads from elsewhere in the body to the liver. Liver metastasis is the more common of the two liver cancers. Instances of liver cancer are increasing globally.
Hashem B. El-Serag is a Palestinian-American physician and medical researcher best known for his research in liver cancer, hepatocellular carcinoma (HCC) and the hepatitis C virus. He serves as the Margaret M. and Albert B. Alkek Chairman of the Department of Medicine at Baylor College of Medicine as well as the co-director of the Texas Medical Center Digestive Disease Center. El-Serag previously served as president of the American Gastroenterological Association and Editor-in-Chief of Clinical Gastroenterology and Hepatology.
Mary Rita Cooke Greenwood is an American academic and nutritionist.
Ruth Lillian Kirschstein was an American pathologist and science administrator at the National Institutes of Health (NIH). Kirschstein served as director of the National Institute of General Medical Sciences, deputy director of NIH in the 1990s, and acting director of the NIH in 1993 and 2000-2002.
Leona D. Samson is the Uncas and Helen Whitaker Professor and American Cancer Society Research Professor of Biological Engineering at the Massachusetts Institute of Technology, where she served as the Director of the Center for Environmental Health Sciences from 2001 to 2012. Before her professorship at MIT, she held a professorship at the Harvard School of Public Health. She is on the editorial board of the journal DNA Repair. Her research interests focus on "methods for measuring DNA repair capacity (DRC) in human cells", research the National Institute of Health recognized as pioneering in her field, for which the NIH granted her the National Institutes of Health Director's Pioneer Award.
Vivian Winona Pinn is an American physician-scientist and pathologist known for her advocacy of women's health issues and concerns, particularly for ensuring that federally funded medical studies include female patients, and well as encouraging women to follow medical and scientific careers. She served as associate director for research on women's health at the National Institutes of Health (NIH), concurrently was the inaugural director of NIH's Office of Research on Women's Health. Pinn previously taught at Harvard University, Tufts University, and Howard University College of Medicine. Since retiring from NIH in 2011, Pinn has continued working as a senior scientist emerita at the Fogarty International Center.
Randi J. Hagerman is an American physician and the medical director of MIND Institute at the University of California, Davis. She works for the pediatrics department under the division of child development and behavior. She is an internationally recognized researcher in the field of genetics of autism spectrum disorder with special focus on genomic instability. Along with her husband Paul Hagerman, she discovered the Fragile X-associated tremor/ataxia syndrome (FXTAS), a neurological disorder that affects older male and rare female carriers of fragile X. She was recognized on a list of the world's top female scientists
Susan Marie Stover is a professor of veterinary anatomy at the University of California, Davis School of Veterinary Medicine and director of the J.D. Wheat Veterinary Orthopedic Research Laboratory. One of the focuses of her wide-ranging research is musculoskeletal injuries in racehorses, particularly catastrophic breakdowns. Her identification of risk factors has resulted in improved early detection and changes to horse training and surgical repair methods. On July 30, 2016, Stover received the Lifetime Excellence in Research Award from the American Veterinary Medical Association. In August 2016, she was selected for induction into the University of Kentucky Equine Research Hall of Fame.
Steven R. Tannenbaum was born and grew up in the Rockaways of Queens, New York City. He attended the Hebrew Institute of Long Island through 9th grade, then moved to Hewlett, Long Island where he graduated from Woodmere H.S. in 1954. He attended the Massachusetts Institute of Technology from 1954-1962, earning a B.S. in Food Technology in 1958 and a PhD. in Food Science in 1962. He was then appointed to Assistant Professor in 1964 in the Department of Food Science and Technology leading up to Full Professor in 1974. Throughout his career he was mentored by Samuel A. Goldblith up until his death in 2001. In 1973 Tannenbaum did a sabbatical at the Hebrew University of Jerusalem, where he decided to switch his career into cancer research at the suggestion of Gerald Wogan.
George K. Michalopoulos is a Greek-American pathologist and academic. He served as Maud L. Menten Professor of Experimental Pathology and Chair of the Department of Pathology at the University of Pittsburgh and UPMC from 1991 to 2023.
Jonna Ann Keener Mazet is an American veterinarian, epidemiologist and a Distinguished Professor of Epidemiology and Disease Ecology at the University of California, Davis. Since 2021, she has served as the Vice Provost of Grand Challenges at the University of California, Davis where she provides leadership for transdisciplinary research and solution-oriented activities dedicated to global health problem solving across. UC Davis Grand Challenges focuses on developing climate solutions, preventing and responding to emerging health threats, promoting sustainable food systems, and reimagining the role of land-grant universities. Dr. Mazet is known for her long-standing achievements and contributions to operationalizing the One Health approach, which is now a key component of the Quadripartite Organizations core mandates for addressing health challenges. In 2009, Dr. Mazet founded the One Health Institute at the University of California, Davis and served as the Executive Director until July 2020. Recognized for her innovative and holistic approach to emerging environmental and global health threats, she is an elected member of the National Academy of Medicine and a fellow of the American Association for the Advancement of Science.
Nancy E. Lane is an American rheumatologist. She is an Endowed Professor of Medicine, Rheumatology, and Aging Research at the University of California, Davis and director of the UC Davis Musculoskeletal Diseases of Aging Research Group. She has also sat on the editorial boards of Nature Reviews Rheumatology, Rheumatology,Seminars in Arthritis and Rheumatism,Arthritis & Rheumatology, and The Journal of Rheumatology. Her work on aging and glucocorticoids in cell populations is internationally recognized.
Allison Brashear is an American neurologist. As of October 2021, she has accepted a position as Vice President for Health Sciences and Dean of the Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo, New York. She was dean of the UC Davis School of Medicine until November 2021 and previously served as the Walter C. Teagle Endowed Chair of Neurology at Wake Forest School of Medicine.
Kathryn Gertrude Dewey is an American nutritionist. She is a Distinguished Professor Emerita in the Department of Nutrition at the University of California, Davis. Her studies in nutrition led to adaptations to the World Health Organization's recommendations for infants.
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Robert Cardiff is an American emeritus professor of pathology, educator, former chair of pathology at University of California, Davis, and scientist, best known for his contributions to biomedical research.