AKIRIN2

AKIRIN2
Identifiers
Aliases	AKIRIN2 , C6orf166, FBI1, dJ486L4.2, akirin 2
External IDs	OMIM: 615165 MGI: 1889364 HomoloGene: 9988 GeneCards: AKIRIN2
Gene location (Human) Chr. Chromosome 6 (human) [1] Band 6q15 Start 87,674,860 bp [1] End 87,702,233 bp [1]
Gene location (Mouse) Chr. Chromosome 4 (mouse) [2] Band 4|4 A5 Start 34,550,937 bp [2] End 34,566,908 bp [2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • enzyme binding • GO:0001948 protein binding Cellular component • transcription repressor complex • nucleus • nucleoplasm Biological process • multicellular organism development • positive regulation of endopeptidase activity • response to lipopolysaccharide • innate immune response • negative regulation of transcription, DNA-templated • regulation of transcription, DNA-templated • negative regulation of transcription by RNA polymerase II • negative regulation of gene expression • transcription, DNA-templated • positive regulation of cell population proliferation • positive regulation of interleukin-6 production • positive regulation of transcription by RNA polymerase II • immune system process • embryo development ending in birth or egg hatching Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	55122	433693
Ensembl	ENSG00000135334	ENSMUSG00000028291
UniProt	Q53H80	B1AXD8
RefSeq (mRNA)	NM_018064	NM_001007589 NM_026019
RefSeq (protein)	NP_060534	NP_001007590
Location (UCSC)	Chr 6: 87.67 – 87.7 Mb	Chr 4: 34.55 – 34.57 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Akirin-2 is a protein that in humans is encoded by the AKIRIN2 gene. ^[5]

References

1. GRCh38: Ensembl release 89: ENSG00000135334 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000028291 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: C6orf166 chromosome 6 open reading frame 166".

External links

• Human AKIRIN2 genome location and AKIRIN2 gene details page in the UCSC Genome Browser .

Further reading

• Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (Nov 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi: 10.1016/j.cell.2006.09.026 . PMID   17081983. S2CID   7827573.
• Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID   16189514. S2CID   4427026.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (Oct 1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Maruyama K, Sugano S (Jan 1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.