Bis(chloromethyl) ketone

Last updated
Bis(chloromethyl) ketone
1,3-Dichloroacetone.svg
1,3-Dichloro-2-propanone-3D-balls-by-AHRLS-2012.png
1,3-Dichloro-2-propanone-3D-sticks-by-AHRLS-2012.png
1,3-Dichloro-2-propanone-3D-vdW-by-AHRLS-2012.png
Names
Preferred IUPAC name
1,3-Dichloropropan-2-one
Other names
1,3-Dichloroacetone
α,α'-Dichloroacetone
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.007.806 OOjs UI icon edit-ltr-progressive.svg
EC Number
  • 208-585-6
PubChem CID
UNII
UN number 2649
  • InChI=1S/C3H4Cl2O/c4-1-3(6)2-5/h1-2H2
    Key: SUNMBRGCANLOEG-UHFFFAOYSA-N
  • InChI=1/C3H4Cl2O/c4-1-3(6)2-5/h1-2H2
    Key: SUNMBRGCANLOEG-UHFFFAOYAE
  • ClCC(=O)CCl
Properties
C3H4Cl2O
Molar mass 126.96 g·mol−1
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
Extremely toxic. Dangerous to the skin and eyes
GHS labelling:
GHS-pictogram-acid.svg GHS-pictogram-skull.svg GHS-pictogram-silhouette.svg GHS-pictogram-pollu.svg
Danger
H300, H310, H314, H330, H341, H410
P201, P202, P260, P262, P264, P270, P271, P273, P280, P281, P284, P301+P310, P301+P330+P331, P302+P350, P303+P361+P353, P304+P340, P305+P351+P338, P308+P313, P310, P320, P321, P322, P330, P361, P363, P391, P403+P233, P405, P501
NFPA 704 (fire diamond)
4
1
0
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Bis(chloromethyl) ketone is a chemical substance with formula C
3
H
4
Cl
2
O
. It is a solid, and is used in the making of citric acid. Exposures such as contact or inhalation of bis(chloromethyl) ketone can result in irritation or damage to skin, eyes, throat, lungs, liver and kidneys, as well as headaches and fainting. [1]

Contents

Bis(chloromethyl) ketone is a substance which is classified as an extremely hazardous substance in the United States as defined in Section 302 of the U.S. Emergency Planning and Community Right-to-Know Act (42 U.S.C. 11002), and is subject to strict reporting requirements by facilities which produce, store, or use it in significant quantities. [2]

See also

Related Research Articles

<span class="mw-page-title-main">Emergency Planning and Community Right-to-Know Act</span> 1986 United States law

The Emergency Planning and Community Right-to-Know Act of 1986 is a United States federal law passed by the 99th United States Congress located at Title 42, Chapter 116 of the U.S. Code, concerned with emergency response preparedness.

This is the list of extremely hazardous substances defined in Section 302 of the U.S. Emergency Planning and Community Right-to-Know Act. The list can be found as an appendix to 40 C.F.R. 355. Updates as of 2006 can be seen on the Federal Register, 71 FR 47121.

<span class="mw-page-title-main">Chloromethyl methyl ether</span> Chemical compound

Chloromethyl methyl ether (CMME) is a compound with formula CH3OCH2Cl. A colorless liquid, it is a chloroalkyl ether. It is used as an alkylating agent. In organic synthesis, it is used for introducing the methoxymethyl ether (MOM) protecting group, and is thus often called MOM-Cl or MOM chloride. It also finds application as a chloromethylating agent in some variants of the Blanc chloromethylation.

<span class="mw-page-title-main">Bis(chloromethyl) ether</span> Chemical compound

Bis(chloromethyl) ether is an organic compound with the chemical formula (CH2Cl)2O. It is a colourless liquid with an unpleasant suffocating odour and it is one of the chloroalkyl ethers. Bis(chloromethyl) ether was once produced on a large scale, but was found to be highly carcinogenic and thus such production has ceased.

<span class="mw-page-title-main">Coumaphos</span> Chemical compound

Coumaphos is a nonvolatile, fat-soluble phosphorothioate with ectoparasiticide properties: it kills insects and mites. It is well known by a variety of brand names as a dip or wash, used on farm and domestic animals to control ticks, mites, flies and fleas.

<span class="mw-page-title-main">Chlorophacinone</span> Chemical compound

Chlorophacinone is an anticoagulant used as a rodenticide. It is classified as an extremely hazardous substance in the United States as defined in Section 302 of the U.S. Emergency Planning and Community Right-to-Know Act and is subject to strict reporting requirements by facilities which produce, store, or use it in significant quantities.

<span class="mw-page-title-main">Chloroxuron</span> Chemical compound

Chloroxuron is an organic compound with the chemical formula C15H15ClN2O2 used as an herbicide. It is classified as an extremely hazardous substance in the United States as defined in Section 302 of the U.S. Emergency Planning and Community Right-to-Know Act (42 U.S.C. 11002), and is subject to strict reporting requirements by facilities which produce, store, or use it in significant quantities.

<span class="mw-page-title-main">Isobenzan</span> Chemical compound

Isobenzan (telodrin) is a highly toxic organochloride insecticide. It was produced only in the period from 1958 to 1965 and its use has been since discontinued. It is a persistent organic pollutant that can remain in soil for 2 to 7 years, and the biological half-life of isobenzan in human blood is estimated to be about 2.8 years.

<span class="mw-page-title-main">Azinphos-ethyl</span> Chemical compound

Azinphos-ethyl was a broad-spectrum organophosphate insecticide.

<span class="mw-page-title-main">Cyanophos</span> Chemical compound

Cyanophos is a cholinesterase inhibitor used as an insecticide and avicide; for example, against rice stem borers and house flies. It is part of the chemical class of organophosphorus compounds, and is a yellow to reddish-yellow transparent liquid.

<span class="mw-page-title-main">Bitoscanate</span> Chemical compound

Bitoscanate is an organic chemical compound used in the treatment of hookworms. It is classified as an extremely hazardous substance in the United States as defined in Section 302 of the U.S. Emergency Planning and Community Right-to-Know Act, and is subject to strict reporting requirements by facilities which produce, store, or use it in significant quantities.

<span class="mw-page-title-main">Chlorflurazole</span> Chemical compound

Chlorflurazole is an herbicide. It is classified as an extremely hazardous substance in the United States as defined in Section 302 of the U.S. Emergency Planning and Community Right-to-Know Act, and is subject to strict reporting requirements by facilities which produce, store, or use it in significant quantities.

<span class="mw-page-title-main">Bicyclo(2.2.1)heptane-2-carbonitrile</span> Chemical compound

Bicyclo[2.2.1]heptane-2-carbonitrile is a chemical which is classified as an extremely hazardous substance in the United States as defined in Section 302 of the U.S. Emergency Planning and Community Right-to-Know Act, and is subject to strict reporting requirements by facilities which produce, store, or use it in significant quantities.

<span class="mw-page-title-main">Chlormephos</span> Chemical compound

Chlormephos (chemical formula: C5H12ClO2PS2) is an organothiophosphate insecticide. It is classified as an extremely hazardous substance in the United States as defined in Section 302 of the U.S. Emergency Planning and Community Right-to-Know Act (42 U.S.C. 11002), and is subject to strict reporting requirements by facilities which produce, store, or use it in significant quantities.

<span class="mw-page-title-main">Chlorthiophos</span> Chemical compound

Chlorthiophos is an organophosphorus pesticide. It is a mixture of isomers:

<span class="mw-page-title-main">3,4-Dichlorophenyl isocyanate</span> Chemical compound

3,4-Dichlorophenyl isocyanate is a chemical compound used as a chemical intermediate and in organic synthesis. It is a solid, and ranges in colour from white to yellow. It is an irritant for tissues including eyes and mucous membranes, and inhalation of dust from the chemical is poisonous. It can be used industrially in the preparation of triclocarban by reaction with p-chloroaniline.

<span class="mw-page-title-main">Isopropylmethylpyrazolyl dimethylcarbamate</span> Chemical compound

Isopropylmethylpyrazolyl dimethylcarbamate is a chemical compound used in Europe in aphicides and insecticides. As of 1998, the United States Environmental Protection Agency listed it as an unregistered pesticide in the United States. In China, it is used under the name isolan.

Lactonitrile is the organic compound with the formula CH3CH(OH)CN. It is an intermediate in the industrial production of ethyl lactate and lactic acid. It is the cyanohydrin of acetaldehyde. It is a colorless liquid, although degraded samples can appear yellow.

<span class="mw-page-title-main">3,3-Bis(chloromethyl)oxetane</span> Chemical compound

3,3-Bis(chloromethyl)oxetane (BCMO) is a useful monomer in the field of energetic materials for synthesis of poly(bis oxetane, which is being researched by numerous militaries around the world. Poly-BAMO is an energetic polymer that have potential to replace the current propellant binder formulations.

<span class="mw-page-title-main">Oxydisulfoton</span> Chemical compound

Oxydisulfoton is a chemical compound used as an acaricide and insecticide. It is classified as an extremely hazardous substance in the United States as defined in Section 302 of the U.S. Emergency Planning and Community Right-to-Know Act, and is subject to strict reporting requirements by facilities which produce, store, or use it in significant quantities.

References

  1. Hazardous Substance Fact Sheet from the New Jersey Department of Health and Senior Services
  2. 40 C.F.R.: Appendix A to Part 355—The List of Extremely Hazardous Substances and Their Threshold Planning Quantities (PDF) (Report) (July 1, 2008 ed.). Government Printing Office. Archived from the original (PDF) on February 25, 2012. Retrieved October 29, 2011.