Boonein

Last updated
Boonein
Boonein.svg
Names
Preferred IUPAC name
(4aS,6S,7R,7aS)-6-Hydroxy-7-methylhexahydrocyclopenta[c]pyran-1(3H)-one
Identifiers
3D model (JSmol)
ChemSpider
PubChem CID
UNII
  • InChI=1S/C9H14O3/c1-5-7(10)4-6-2-3-12-9(11)8(5)6/h5-8,10H,2-4H2,1H3/t5-,6-,7-,8+/m0/s1
    Key: WJMOFJJTTHNUOH-DKXJUACHSA-N
  • O=C1OCC[C@H]2C[C@H](O)[C@H](C)[C@@H]12
Properties
C9H14O3
Molar mass 170.208 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Boonein is an iridoid isolated from Alstonia boonei , a medicinal tree of West Africa. [2]

Related Research Articles

<span class="mw-page-title-main">Apocynaceae</span> Dogbane and oleander family of flowering plants

Apocynaceae is a family of flowering plants that includes trees, shrubs, herbs, stem succulents, and vines, commonly known as the dogbane family, because some taxa were used as dog poison. Members of the family are native to the European, Asian, African, Australian, and American tropics or subtropics, with some temperate members. The former family Asclepiadaceae is considered a subfamily of Apocynaceae and contains 348 genera. A list of Apocynaceae genera may be found here.

<i>Alstonia</i> Genus of flowering plants

Alstonia is a widespread genus of evergreen trees and shrubs, of the family Apocynaceae. It was named by Robert Brown in 1811, after Charles Alston (1685–1760), professor of botany at Edinburgh from 1716 to 1760.

<span class="mw-page-title-main">Golden Stool</span> Throne of Ashanti kings

The Golden Stool is the royal and divine throne of kings of the Ashanti people and the ultimate symbol of power in Asante. According to legend, Okomfo Anokye, High Priest and one of the two chief founders of the Asante Confederacy, caused the stool to descend from the sky and land on the lap of the first Asante king, Osei Tutu. Such seats were traditionally symbolic of a chieftain's leadership, but the Golden Stool is believed to house the spirit of the Asante nation—living, dead and yet to be born.

<i>Alstonia scholaris</i> Species of tree

Alstonia scholaris, commonly called blackboard tree, scholar tree, milkwood or devil's tree in English, is an evergreen tropical tree in the Dogbane Family (Apocynaceae). It is native to southern China, tropical Asia (mainly the Indian subcontinent and Southeast Asia)and Australasia, where it is a common ornamental plant. It is a toxic plant, but is used traditionally for myriad diseases and complaints.

<span class="mw-page-title-main">Loganin</span> Chemical compound

Loganin is one of the best-known of the iridoid glycosides. It is named for the Loganiaceae, having first been isolated from the seeds of a member of that plant family, namely those of Strychnos nux-vomica. It also occurs in Alstonia boonei (Apocynaceae), a medicinal tree of West Africa and in the medicinal/entheogenic shrub Desfontainia spinosa (Columelliaceae) native to Central America and South America.

<span class="mw-page-title-main">Echitamidine</span> Chemical compound

Echitamidine is an indole alkaloid isolated from Alstonia boonei. Its laboratory synthesis has been reported.

<span class="mw-page-title-main">Nareline</span> Chemical compound

Nareline is a bio-active alkaloid isolated from Alstonia boonei, a medicinal tree of West Africa.

<span class="mw-page-title-main">Picrinine</span> Chemical compound

Picrinine is a bio-active alkaloid from Alstonia boonei, a medicinal tree of West Africa.

<span class="mw-page-title-main">Scholarine</span> Chemical compound

Scholarine is an alkaloid isolated initially from Alstonia scholaris by Banerji and Siddhanta. Subsequently, it was obtained from the West African tree Alstonia boonei. The derivative N-Formylscholarine has been isolated from the fruit pods of Alstonia scholaris.

<span class="mw-page-title-main">Pseudoakuammigine</span> Chemical compound

Pseudoakuammigine is a bio-active alkaloid from Alstonia boonei, a medicinal tree from West Africa.

<span class="mw-page-title-main">Picralinal</span> Chemical compound

Picralinal is a bio-active alkaloid from Alstonia scholaris, a medicinal tree of West Africa.

<span class="mw-page-title-main">Rhazine</span> Chemical compound

Rhazine is an alkaloid isolated from Alstonia boonei, a tree of West Africa.

<span class="mw-page-title-main">Scholaricine</span> Chemical compound

Scholaricine is an alkaloid that has been isolated from Alstonia boonei, a tree of West Africa.

<span class="mw-page-title-main">Alstonine</span> Chemical compound

Alstonine is an indoloquinolizidine alkaloid and putative antipsychotic constituent of various plant species including Alstonia boonei, Catharanthus roseus, Picralima nitida, Rauwolfia caffra and Rauwolfia vomitoria. In preclinical studies alstonine attenuates MK-801-induced hyperlocomotion, working memory deficit and social withdrawal. It also possesses anxiolytic-like effects in preclinical studies, attenuates amphetamine-induced lethality and stereotypy as well as apomorphine-induced stereotypy, and attenuates haloperidol-induced catalepsy. These effects appear to be mediated by stimulation of the 5-HT2C receptor. In addition, alstonine, similarly to clozapine, indirectly inhibits the reuptake of glutamate in hippocampal slices. Unlike clozapine however, the effect of which is abolished by the D2 receptor agonist apomorphine, alstonine requires 5-HT2A and 5-HT2C receptors to produce this effect, as it is abolished by antagonists of these receptors. Also unlike clozapine, alstonine lacks pro-convulsant activity in mice.

Alstonia boonei is a very large, deciduous, tropical-forest tree belonging to the Dogbane Family (Apocynaceae). It is native to tropical West Africa, with a range extending into Ethiopia and Tanzania. Its common name in the English timber trade is cheese wood, pattern wood or stool wood while its common name in the French timber trade is emien.

Bishnupada Mukerjee or Bishnupada Mukhopadhyaya was an Indian pharmacologist and orthopedic surgeon, known for his contributions in the fields of pharmacological research and standardization of drugs in India. The Government of India honoured him in 1962, with the award of Padma Shri, the fourth highest Indian civilian award for his services to the nation.

<span class="mw-page-title-main">Aciduliprofundum boonei</span> Species of archaeon

"Candidatus Aciduliprofundum boonei" is an obligate thermoacidophilic candidate species of archaea belonging to the phylum "Euryarchaeota". Isolated from acidic hydrothermal vent environments, "Ca. A. boonei" is the first cultured representative of a biogeochemically significant clade of thermoacidophilic archaea known as the "Deep-Sea Hydrothermal Vent Euryarchaeota 2 (DHVE2)".

Pulai is a suburban area in the city of Iskandar Puteri, Mukim Pulai, district Johor Bahru, state of Johor, Malaysia

<i>Alstonia congensis</i> Species of plant

Alstonia congensis, is a tree within the Apocynaceae family and one of two African species within the Alstonia genus, the other being the Alstonia boonei De Wild. Both have similar morphological characteristics.

Mpem and Djim National Park is a protected area in Cameroon. The park was designated by the government of Cameroon in 2004, and covers an area of 974.8 km2.

References

  1. Dictionary of Terpenoids. CRC Press. 1991. p. 56. ISBN   9780412257704.
  2. Adotey, John Prosper Kwaku; Adukpo, Genevieve Etornam; Opoku Boahen, Yaw; Armah, Frederick Ato (2012). "A Review of the Ethnobotany and Pharmacological Importance of Alstonia boonei De Wild (Apocynaceae)". ISRN Pharmacology. 2012: 1–9. doi: 10.5402/2012/587160 . PMC   3413980 . PMID   22900200.