CNTLN

Last updated
CNTLN
Identifiers
Aliases CNTLN , C9orf101, C9orf39, bA340N12.1, centlein
External IDs OMIM: 611870 MGI: 2443104 HomoloGene: 9805 GeneCards: CNTLN
Gene location (Human)
Ideogram human chromosome 9.svg
Chr. Chromosome 9 (human) [1]
Human chromosome 9 ideogram.svg
HSR 1996 II 3.5e.svg
Red rectangle 2x18.png
Band 9p22.2Start17,134,982 bp [1]
End17,503,923 bp [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001114395
NM_001286984
NM_001286985
NM_017738
NM_001365029

Contents

NM_175275
NM_177385

RefSeq (protein)

NP_001107867
NP_001273913
NP_001273914
NP_060208
NP_001351958

NP_780484
NP_796359

Location (UCSC) Chr 9: 17.13 – 17.5 Mb Chr 4: 84.88 – 85.13 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Centlein, centrosomal protein is a protein in humans that is encoded by the CNTLN gene. [5]

Related Research Articles

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CNTRL

Centriolin is a protein that in humans is encoded by the CNTRL gene. It was previously known as CEP110.

CEP250

Centrosome-associated protein CEP250 is a protein that in humans is encoded by the CEP250 gene. This gene encodes a core centrosomal protein required for centriole-centriole cohesion during interphase of the cell cycle. The encoded protein dissociates from the centrosomes when parental centrioles separate at the beginning of mitosis. The protein associates with and is phosphorylated by NIMA-related kinase 2, which is also associated with the centrosome. Furthermore, CEP135 is also required for the centriolar localization of CEP250.

CEP170

Centrosomal protein 170kDa, also known as CEP170, is a protein that in humans is encoded by the CEP170 gene.

CEP68

Centrosomal protein of 68 kDa is a protein that in humans is encoded by the CEP68 gene. CEP68 is required for centrosome cohesion. It decorates fibres emanating from the proximal ends of centrioles. During mitosis, CEP68 dissociates from centrosomes. CEP68 and rootletin depend both on each other for centriole association, and both also require CEP250 for their function.

SOSTDC1

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PSKH1

Serine/threonine-protein kinase H1 is an enzyme that in humans is encoded by the PSKH1 gene.

CEP63

Centrosomal protein of 63 kDa is a protein that in humans is encoded by the CEP63 gene. Several alternatively spliced transcript variants have been found, but their biological validity has not been determined.

CEP57

Centrosomal protein of 57 kDa is a protein that in humans is encoded by the CEP57 gene.

CEP72

Centrosomal protein of 72 kDa is a protein that in humans is encoded by the CEP72 gene.

CEP70

Centrosomal protein of 70 kDa is a protein that in humans is encoded by the CEP70 gene. The protein interacts with γ-tubulin through its coiled coil domains to localize at the centrosome. CEP70 is involved in organizing microtubules in interphase cells and is required for proper organization and orientation of the mitotic spindle.

CEP135

Centrosomal protein of 135 kDa is a protein that in humans is encoded by the CEP135 gene. It is part of the centrosome throughout the cell cycle, being distributed in the pericentriolar material. CEP135 is required for the centriolar localization of CEP250.

LCA5

Lebercilin, also known as leber congenital amaurosis 5 (LCA5), is a protein that in humans is encoded by the LCA5 gene. This protein is thought to be involved in centrosomal or ciliary functions.

KRT79

Keratin 79 also known as KRT79 is a protein which humans is encoded by the KRT79 gene.

IFT81

Intraflagellar transport protein 81 homolog is a protein that in humans is encoded by the IFT81 gene. Together with IFT74/72 it forms a core complex to build IFT particles which are required for cilium formation. Additionally, it interacts with basal body components as CEP170 which regulates the disassembly of the cilium.

CEP97

Centrosomal protein of 97 kDa (Cep97), also known as leucine-rich repeat and IQ domain-containing protein 2 (LRRIQ2), is a protein that in humans is encoded by the CEP97 gene.

CEP120 Protein-coding gene in the species Homo sapiens

Centrosomal protein of 120 kDa (Cep120), also known as coiled-coil domain-containing protein 100, is a protein that in humans is encoded by the CEP120 gene.

CEP152

Centrosomal protein of 152 kDa, also known as Cep152, is a protein that in humans is encoded by the CEP152 gene. It is the ortholog of the Drosophila melanogaster gene asterless (asl) and both are required for centriole duplication.

CEP104

Centrosomal protein 104kDa is a protein that in humans is encoded by the CEP104 gene. Like its Chlamydomonas ortholog, FAP256, it has been shown to localize to the distal ends of both centrioles in the absence of a cilium. During cilium formation, it is found at the tip of the elongating cilium.

CEP128

Centrosomal protein 128kDa is a protein that in humans is encoded by the CEP128 gene.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000044459 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000038070 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: Centlein, centrosomal protein".

Further reading