CSDC2

CSDC2
Identifiers
Aliases	CSDC2 , PIPPIN, dJ347H13.2, cold shock domain containing C2
External IDs	OMIM: 617689 MGI: 2146027 HomoloGene: 8701 GeneCards: CSDC2
Gene location (Human)
Chr.	Chromosome 22 (human)
End	41,577,741 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	81,835,142 bp
RNA expression pattern
	Top expressed in
	left ventricle; ; right coronary artery; ; Right adrenal gland; ; popliteal artery; ; left coronary artery; ; optic nerve; ; canal of the cervix; ; ascending aorta; ; cerebellar vermis; ; right ventricle;
	Top expressed in
	pontine nuclei; ; medial geniculate nucleus; ; medial vestibular nucleus; ; medial dorsal nucleus; ; dorsal tegmental nucleus; ; inferior colliculus; ; motor neuron; ; cerebellar cortex; ; cerebellar vermis; ; subiculum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding ; protein binding ; RNA binding ; nucleic acid binding ; mRNA 3'-UTR binding ; transcription factor binding ;
Cellular component	nucleus ; cytoplasm ;
Biological process	mRNA processing ; regulation of transcription, DNA-templated ; regulation of mRNA stability ;
	Sources:Amigo / QuickGO
Orthologs
	27254
	105859
	ENSG00000172346
	ENSMUSG00000042109
	Q9Y534
	Q91YQ3
	NM_014460
	NM_145473
	NP_055275
	NP_663448
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated March 05, 2023

Cold shock domain-containing protein C2 is a protein that in humans is encoded by the CSDC2 gene.^[5]^[6]^[7]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000172346 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000042109 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Castiglia D, Scaturro M, Nastasi T, Cestelli A, Di Liegro I (Mar 1996). "PIPPin, a putative RNA-binding protein specifically expressed in the rat brain". Biochem Biophys Res Commun. 218 (1): 390–4. doi:10.1006/bbrc.1996.0068. PMID 8573167.
↑ Raimondi L, D'Asaro M, Proia P, Nastasi T, Di Liegro I (May 2003). "RNA-binding ability of PIPPin requires the entire protein". J Cell Mol Med. 7 (1): 35–42. doi:10.1111/j.1582-4934.2003.tb00200.x. PMC 6740078 . PMID 12767259.
↑ "Entrez Gene: CSDC2 cold shock domain containing C2, RNA binding".

External links

Human CSDC2 genome location and CSDC2 gene details page in the UCSC Genome Browser .

Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146 . PMID 9110174.
Nastasi T, Scaturro M, Bellafiore M, et al. (1999). "PIPPin is a brain-specific protein that contains a cold-shock domain and binds specifically to H1 degrees and H3.3 mRNAs". J. Biol. Chem. 274 (34): 24087–93. doi: 10.1074/jbc.274.34.24087 . PMID 10446180.
Dunham I, Shimizu N, Roe BA, et al. (1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–95. Bibcode:1999Natur.402..489D. doi: 10.1038/990031 . PMID 10591208.
Nastasi T, Muzi P, Beccari S, et al. (2001). "Specific neurons of brain cortex and cerebellum are PIPPin positive". NeuroReport. 11 (10): 2233–6. doi:10.1097/00001756-200007140-00034. PMID 10923677. S2CID 28313328.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Schäfer C, Steffen H, Krzykowski KJ, et al. (2003). "CRHSP-24 phosphorylation is regulated by multiple signaling pathways in pancreatic acinar cells". Am. J. Physiol. Gastrointest. Liver Physiol. 285 (4): G726–34. doi:10.1152/ajpgi.00111.2003. PMID 12801884.
Collins JE, Wright CL, Edwards CA, et al. (2005). "A genome annotation-driven approach to cloning the human ORFeome". Genome Biol. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMC 545604 . PMID 15461802.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129 . PMID 16344560.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000172346 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000042109 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8573167-5] Castiglia D, Scaturro M, Nastasi T, Cestelli A, Di Liegro I (Mar 1996). "PIPPin, a putative RNA-binding protein specifically expressed in the rat brain". Biochem Biophys Res Commun. 218 (1): 390–4. doi:10.1006/bbrc.1996.0068. PMID 8573167.

[pmid12767259-6] Raimondi L, D'Asaro M, Proia P, Nastasi T, Di Liegro I (May 2003). "RNA-binding ability of PIPPin requires the entire protein". J Cell Mol Med. 7 (1): 35–42. doi:10.1111/j.1582-4934.2003.tb00200.x. PMC 6740078 . PMID 12767259.

[entrez-7] "Entrez Gene: CSDC2 cold shock domain containing C2, RNA binding".

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CSDC2

Contents

Related Research Articles

References

External links

Further reading