EPPI-Centre

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The Evidence for Policy and Practice Information and Co-ordinating Centre (EPPI-Centre) is part of the Faculty of Education and Society at the University College of London. Its work is concerned with systematic reviews which use transparent and explicit methodologies for reviewing research evidence in order to be clear about what we know from research and how we know it.

Contents

Methods for Research Synthesis

A major focus of the EPPI-Centre is the development of methods of systematic reviews including systematic mapping and synthesis. The Centre is the Methods for Research Synthesis (MRS) Node of the Economic and Social Research Council (ESRC) National Centre for Research Methods.

The Centre has adapted the model of systematic reviews that has been widely developed in healthcare to address a broader range of questions and methodologies relevant to public policy research such as statistical, narrative and conceptual synthesis. [1]

Working with a range of users

The EPPI-Centre's programme of work seeks to develop ways of working with various groups of research and service ‘users’ throughout the review process, including deciding which topics need most urgently to be reviewed, and analyzing and disseminating the results of reviews. [2] A particular aim is to explore the perspectives and participation of those people who are, or represent, people receiving a service or who are affected by the service in some other way. This might include: patients in a clinical encounter; students in a classroom; people receiving, missing or avoiding health promotion interventions; or students and parents in relation to an education policy. [3]

Evidence Library

The EPPI-Centre conducts systematic reviews of research evidence across a range of topics. Major areas include education, health promotion, employment, social care and justice. The reviews on these topics can be found in an Online Evidence Library, which provides evidence overviews of broad topic areas as well as summaries and full reports of specific reviews conducted or supported by the EPPI-Centre.

Collaborative Partnerships

Work at the EPPI-Centre is funded by a range of research councils, government departments and charities and national and international partners. The EPPI-centre has strong links with two international collaborations concerned with policy-relevant reviews of research evidence: the Cochrane Collaboration in health care and the Campbell collaboration for social interventions.

Teaching and Learning

The EPPI-Centre offers a large programme of training and workshops on methodological and practical aspects of systematic research synthesis, including an MSc in Research for Public Policy and Practice. The Centre offers face-to-face and online distance short courses in Systematic reviews for policy and practice; Participative research and policy; and Methods for research synthesis. [4]

EPPI-Reviewer software

EPPI-Reviewer [5] is a web application that enables researchers to manage the entire lifecycle of a review in a single location. Users are able to upload studies for screening, complete keywording and data extractions and analyse the results over the internet. Analytical functions include meta-analysis, summary tables and support for qualitative synthesis.

Related Research Articles

Evidence-based medicine (EBM) is "the conscientious, explicit and judicious use of current best evidence in making decisions about the care of individual patients." The aim of EBM is to integrate the experience of the clinician, the values of the patient, and the best available scientific information to guide decision-making about clinical management. The term was originally used to describe an approach to teaching the practice of medicine and improving decisions by individual physicians about individual patients.

Cochrane (organisation) British nonprofit for reviews of medical research (formed 1993)

Cochrane is a British international charitable organisation formed to organise medical research findings to facilitate evidence-based choices about health interventions involving health professionals, patients and policy makers. It includes 53 review groups that are based at research institutions worldwide. Cochrane has approximately 30,000 volunteer experts from around the world.

Cochrane Library Collection of databases in medicine and other healthcare specialties

The Cochrane Library is a collection of databases in medicine and other healthcare specialties provided by Cochrane and other organizations. At its core is the collection of Cochrane Reviews, a database of systematic reviews and meta-analyses which summarize and interpret the results of medical research. The Cochrane Library aims to make the results of well-conducted controlled trials readily available and is a key resource in evidence-based medicine.

National Institute for Health and Care Excellence Non-departmental public body of the Department of Health in the United Kingdom

The National Institute for Health and Care Excellence (NICE) is an executive non-departmental public body of the Department of Health and Social Care in England that publishes guidelines in four areas:

Community health Field of study

Community health is a major field of study within the medical and clinical sciences which focuses on the maintenance, protection, and improvement of the health status of population groups and communities. It is a distinct field of study that may be taught within a separate school of public health or environmental health. The WHO defines community health as:

environmental, social, and economic resources to sustain emotional and physical well being among people in ways that advance their aspirations and satisfy their needs in their unique environment.

Population health Health outcomes of a group of individuals

Population health has been defined as "the health outcomes of a group of individuals, including the distribution of such outcomes within the group". It is an approach to health that aims to improve the health of an entire human population. It has been described as consisting of three components. These are "health outcomes, patterns of health determinants, and policies and interventions".

Evidence-based policy (EBP) is an idea in public policy proposing that policy decisions should be based on, or informed by, rigorously established objective evidence. The implied contrast is with policymaking based on ideology, 'common sense,' anecdotes, and intuitions. It is the government equivalent of the effective altruism movement. Evidence-based policy uses a thorough research method, such as randomized controlled trials (RCT). Good data, analytical skills, and political support to the use of scientific information are typically seen as the crucial elements of an evidence-based approach.

Systematic review Comprehensive review of research literature using systematic methods

Systematic reviews are a type of review that uses repeatable analytical methods to collect secondary data and analyse it. Systematic reviews are a type of evidence synthesis which formulate research questions that are broad or narrow in scope, and identify and synthesize data that directly relate to the systematic review question. While some people might associate 'systematic review' with 'meta-analysis', there are multiple kinds of review which can be defined as 'systematic' which do not involve a meta-analysis. Some systematic reviews critically appraise research studies, and synthesize findings qualitatively or quantitatively. Systematic reviews are often designed to provide an exhaustive summary of current evidence relevant to a research question. For example, systematic reviews of randomized controlled trials are an important way of informing evidence-based medicine, and a review of existing studies is often quicker and cheaper than embarking on a new study.

Evidence-based practice (EBP) is the idea that occupational practices ought to be based on scientific evidence. That at first sight may seem to be obviously desirable, but the proposal has been controversial. Evidence-based practices have been gaining ground since the formal introduction of evidence-based medicine in 1992 and have spread to the allied health professions, education, management, law, public policy, architecture, and other fields. In light of studies showing problems in scientific research, there is also a movement to apply evidence-based practices in scientific research itself. Research into the evidence-based practice of science is called metascience.

The Centre for Reviews and Dissemination (CRD) is a health services research centre based at the University of York, England. CRD was established in January 1994, and aims to provide research-based information for evidence-based medicine. CRD carries out systematic reviews and meta-analyses of healthcare interventions, and disseminates the results of research to decision-makers in the NHS.

Normalization process theory (NPT) is a sociological theory in the field of science and technology studies (STS). The theory deals with the adoption of technological and organizational innovations, originally in the healthcare system, although more recent studies have utilised this theory in evaluating new practices in social care and education settings. It was developed out of the normalization process model.

Implementation research is the systematic study of methods that support the application of research findings and other evidence-based knowledge into policy and practice. It aims to understand the most effective pathways from research to practical application, particularly in areas such as health, education, psychology and management. Intervention research, also known as intervention science, evaluates how various interventions or approaches are adopted and applied in “real world” settings in order to establish an understanding of their effectiveness in different contexts.

Health technology assessment (HTA) is a multidisciplinary process that uses systematic and explicit methods to evaluate the properties and effects of a health technology. Health technology is conceived as any intervention at any point in its lifecycle. HTA aim is to inform "decision-making in order to promote an equitable, efficient, and high-quality health system".  It has other definitions including "a method of evidence synthesis that considers evidence regarding clinical effectiveness, safety, cost-effectiveness and, when broadly applied, includes social, ethical, and legal aspects of the use of health technologies. The precise balance of these inputs depends on the purpose of each individual HTA. A major use of HTAs is in informing reimbursement and coverage decisions by insurers and national health systems, in which case HTAs should include benefit-harm assessment and economic evaluation." And "a multidisciplinary process that summarises information about the medical, social, economic and ethical issues related to the use of a health technology in a systematic, transparent, unbiased, robust manner. Its aim is to inform the formulation of safe, effective, health policies that are patient focused and seek to achieve best value. Despite its policy goals, HTA must always be firmly rooted in research and the scientific method".

National Collaborating Centre for Mental Health

The National Collaborating Centre for Mental Health (NCCMH) is a collaboration between the Royal College of Psychiatrists and the Centre for Outcomes Research and Effectiveness at University College London (UCL). The NCCMH aims to promote the role of evidence synthesis in making informed judgments about healthcare policy. The NCCMH has a history of developing guidelines, conducting systematic reviews and developing implementation guidance for commissioners and service providers. Formed in 2001, on 1 April 2016 a new guideline development centre, the National Guideline Alliance, based at the Royal College of Obstetricians and Gynaecologists took over the clinical guideline programme that had been run by NCCMH.

The discipline of evidence-based toxicology (EBT) strives to transparently, consistently, and objectively assess available scientific evidence in order to answer questions in toxicology, the study of the adverse effects of chemical, physical, or biological agents on living organisms and the environment, including the prevention and amelioration of such effects. EBT has the potential to address concerns in the toxicological community about the limitations of current approaches to assessing the state of the science. These include concerns related to transparency in decision making, synthesis of different types of evidence, and the assessment of bias and credibility. Evidence-based toxicology has its roots in the larger movement towards evidence-based practices.

The Campbell Collaboration is a nonprofit organization that promotes evidence-based decisions and policy through the production of systematic reviews and other types of evidence synthesis. Campbell is composed of coordinating groups that coordinate the production of systematic reviews and evidence gap maps in the following areas: Business & Management, Climate Solutions, Crime & Justice, Disability, Education, International Development, Knowledge Translation & Implementation, Methods, and Social Welfare. It is a sister initiative of Cochrane, with secretariat staff in Oslo and New Delhi.

The United States Cochrane Center (USCC) was one of the 14 centers on the world that facilitated the work of the Cochrane Collaboration. The USCC was the reference center for all 50 US states and US territories, protectorates, and districts: the District of Columbia, American Samoa, Guam, the Northern Mariana Islands, Puerto Rico, and the US Virgin Islands. The USCC was also the reference Center for the following countries: Antigua and Barbuda, Bahamas, Barbados, Belize, Dominica, Grenada, Guam, Guyana, Jamaica, Japan, Saint Kitts and Nevis, Saint Lucia, Saint Vincent and the Grenadines, and Trinidad and Tobago. The USCC discontinued on February 7, 2018.

Evidence-based conservation is the application of evidence in nature conservation management actions and policy making. It is defined as systematically assessing scientific information from published, peer-reviewed publications and texts, practitioners' experiences, independent expert assessment, and local and indigenous knowledge on a specific conservation topic. This includes assessing the current effectiveness of different management interventions, threats and emerging problems and economic factors.

The Health Intervention and Technology Assessment Program (HITAP) is a semi-autonomous research unit under Thailand’s Ministry of Public Health. It was established in 2007 as a non-profit organization in order to take responsibility for appraising a wide range of health technologies and programs, including pharmaceuticals, medical devices, interventions, individual and community health promotion, and disease prevention as well as social health policy to inform policy decisions in Thailand. HITAP assumes an advisory role to health governmental authorities by providing rigorous scientific evidence through professional assessment of health data in support of public decision-making. These assessments cover a range of topics including system design, selection of technologies for assessment, and the actual assessment of those selected and agreed upon by relevant government agencies. In this effort, HITAP publishes research and studies in the following areas: methodological development, databases and guidelines; knowledge transfer and exchange (KTE) and capacity development; technology assessments on drugs, medical devices, medical procedures, disease prevention and health promotion measures; benefit packages of care – mixing screening and treatments; and other public health policies, e.g. evaluation of Thailand’s government compulsory license policy.

Gina Marie Higginbottom is a British academic, nurse, midwife, health visitor and a specialist in international migration and maternity. She is the first nurse of black and minority ethnic (BME) origin to hold a professorial role in a Russell Group university in England.

References

  1. Oakley A, Gough D, Oliver S, Thomas J. The politics of evidence and methodology: lessons from the EPPI-Centre. Evidence & Policy: A Journal of Research, Debate and Practice 2005, 1 (1) 5 – 31
  2. Rees R, Oliver S (2007) User Involvement in systematic reviews: an example from health promotion. In Coren E (ed) Collection of examples of service user and carer participation in systematic reviews. London: Social Care Institute for Excellence
  3. Gough D (2007) Giving voice: evidence-informed policy and practice as a democratizing process. In M Reiss, R DePalma and E Atkinson (Eds) "Marginality and Difference In Education and Beyond." London: Trentham Books
  4. Bird, K (2008) 'An 'objective-centred' approach to course redesign: using learning objectives to integrate e-learning', Reflecting Education, Vol. 4, No. 1: 51-62
  5. Thomas J, Brunton J, Graziosi S (2010) EPPI-Reviewer 4.0: software for research synthesis. EPPI-Centre software. London: Social Science Research Unit, Institute of Education.