The Erdős number describes the "collaborative distance" between mathematician Paul Erdős and another person, as measured by authorship of mathematical papers. The same principle has been applied in other fields where a particular individual has collaborated with a large and broad number of peers.
Six Degrees of Kevin Bacon or Bacon's Law is a parlor game where players challenge each other to arbitrarily choose an actor and then connect them to another actor via a film that both actors have appeared in together, repeating this process to try to find the shortest path that ultimately leads to prolific American actor Kevin Bacon. It rests on the assumption that anyone involved in the Hollywood film industry can be linked through their film roles to Bacon within six steps. The game's name is a reference to "six degrees of separation", a concept that posits that any two people on Earth are six or fewer acquaintance links apart.
Autocrine signaling is a form of cell signaling in which a cell secretes a hormone or chemical messenger that binds to autocrine receptors on that same cell, leading to changes in the cell. This can be contrasted with paracrine signaling, intracrine signaling, or classical endocrine signaling.
Little Bill is an American animated educational television series created by Bill Cosby. It is based on the Little Bill book series, written by Cosby with illustrations by Varnette P. Honeywood. Cosby also composed some of the theme music, appeared in live-action in the show's intro sequence, and voiced the recurring character of Captain Brainstorm. It was Cosby's second animated series, after Fat Albert and the Cosby Kids.
Here Comes Garfield is a 1982 animated television special based on the comic strip Garfield by Jim Davis. It was the first half-hour Garfield TV special. It is directed by Phil Roman and features Lorenzo Music as the voice of Garfield the house cat, as well as the voices of Sandy Kenyon, Henry Corden and Gregg Berger.
A person's Erdős–Bacon number is the sum of one's Erdős number—which measures the "collaborative distance" in authoring academic papers between that person and Hungarian mathematician Paul Erdős—and one's Bacon number—which represents the number of links, through roles in films, by which the person is separated from American actor Kevin Bacon. The lower the number, the closer a person is to Erdős and Bacon, which reflects a small world phenomenon in academia and entertainment.
Tyrosine-protein phosphatase non-receptor type 11 (PTPN11) also known as protein-tyrosine phosphatase 1D (PTP-1D), Src homology region 2 domain-containing phosphatase-2 (SHP-2), or protein-tyrosine phosphatase 2C (PTP-2C) is an enzyme that in humans is encoded by the PTPN11 gene. PTPN11 is a protein tyrosine phosphatase (PTP) Shp2.
Fractalkine, also known as chemokine ligand 1, is a protein that in humans is encoded by the CX3CL1 gene.
Mitogen-activated protein kinase 1, (MAPK 1), also known as ERK2, is an enzyme that in humans is encoded by the MAPK1 gene.
Cbl is a mammalian gene encoding the protein CBL which is an E3 ubiquitin-protein ligase involved in cell signalling and protein ubiquitination. Mutations to this gene have been implicated in a number of human cancers, particularly acute myeloid leukaemia.
Receptor tyrosine-protein kinase erbB-3, also known as HER3, is a membrane bound protein that in humans is encoded by the ERBB3 gene.
Tyrosine-protein phosphatase non-receptor type 1 also known as protein-tyrosine phosphatase 1B (PTP1B) is an enzyme that is the founding member of the protein tyrosine phosphatase (PTP) family. In humans it is encoded by the PTPN1 gene. PTP1B is a negative regulator of the insulin signaling pathway and is considered a promising potential therapeutic target, in particular for treatment of type 2 diabetes. It has also been implicated in the development of breast cancer and has been explored as a potential therapeutic target in that avenue as well.
Dual specificity mitogen-activated protein kinase kinase 3 is an enzyme that in humans is encoded by the MAP2K3 gene.
RAC-gamma serine/threonine-protein kinase is an enzyme that in humans is encoded by the AKT3 gene.
Interferon regulatory factor 2 is a protein that in humans is encoded by the IRF2 gene.
Tyrosine-protein phosphatase non-receptor type 9 is an enzyme that in humans is encoded by the PTPN9 gene.
Fibroblast growth factor 6 is a protein that in humans is encoded by the FGF6 gene.
Hugh David Politzer is an American theoretical physicist and the Richard Chace Tolman Professor of Theoretical Physics at the California Institute of Technology. He shared the 2004 Nobel Prize in Physics with David Gross and Frank Wilczek for their discovery of asymptotic freedom in quantum chromodynamics.
Mitogen-activated protein kinase 12, also known as extracellular signal-regulated kinase 6 (ERK6) or stress-activated protein kinase 3 (SAPK3), is an enzyme that in humans is encoded by the MAPK12 gene.
Events in 1914 in animation.
