Filamin A interacting protein 1 like

FILIP1L
Identifiers
Aliases	FILIP1L , DOC-1, DOC1, GIP130, GIP90, filamin A interacting protein 1-like, filamin A interacting protein 1 like
External IDs	OMIM: 612993 MGI: 1925999 HomoloGene: 37121 GeneCards: FILIP1L
Gene location (Human)
Chr.	Chromosome 3 (human)
End	100,114,513 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	57,393,489 bp
RNA expression pattern
	Top expressed in
	saphenous vein; ; vena cava; ; urethra; ; superficial temporal artery; ; ascending aorta; ; right coronary artery; ; popliteal artery; ; gallbladder; ; Achilles tendon; ; triceps brachii muscle;
	Top expressed in
	ascending aorta; ; external carotid artery; ; hand; ; carotid body; ; aortic valve; ; belly cord; ; lymph node; ; spleen; ; internal carotid artery; ; Epithelium of stomach;
	More reference expression data
	n/a
Gene ontology
Molecular function	molecular function ;
Cellular component	cytoplasm ; membrane ; nucleus ;
Biological process	biological process ;
	Sources:Amigo / QuickGO
Orthologs
	11259
	78749
	ENSG00000168386
	ENSMUSG00000043336
	Q4L180
	Q6P6L0
NM_001042459 ; NM_001282793 ; NM_001282794 ; NM_014890 ; NM_182909 ;
	NM_001370247 ; NM_001387850 ; NM_001387851 ; NM_001387852
	NM_001040397 ; NM_001177871
NP_001035924 ; NP_001269722 ; NP_001269723 ; NP_055705 ; NP_878913 ;
	NP_001357176
	NP_001035487 ; NP_001171342
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated March 04, 2023

Filamin A interacting protein 1 like is a protein that in humans is encoded by the FILIP1L gene. ^[5]

Related Research Articles

Breast cancer type 1 susceptibility protein is a protein that in humans is encoded by the BRCA1 gene. Orthologs are common in other vertebrate species, whereas invertebrate genomes may encode a more distantly related gene. BRCA1 is a human tumor suppressor gene and is responsible for repairing DNA.

Mothers against decapentaplegic homolog 7 or SMAD7 is a protein that in humans is encoded by the SMAD7 gene.

Neural cell adhesion molecule L1-like protein also known as close homolog of L1 (CHL1) is a protein that in humans is encoded by the CHL1 gene.

Filamin A, alpha (FLNA) is a protein that in humans is encoded by the FLNA gene.

Insulin-like growth factor 2 mRNA-binding protein 1 is a protein that in humans is encoded by the IGF2BP1 gene.

Zinc finger protein PLAGL1 is a protein that in humans is encoded by the PLAGL1 gene.

Filamin B, beta (FLNB), also known as Filamin B, beta , is a cytoplasmic protein which in humans is encoded by the FLNB gene.

RAD51 homolog C , also known as RAD51C, is a protein which in humans is encoded by the RAD51C gene.

Microtubule-associated protein RP/EB family member 1 is a protein that in humans is encoded by the MAPRE1 gene.

Microtubule-associated protein RP/EB family member 2 is a protein that in humans is encoded by the MAPRE2 gene.

Protein tyrosine phosphatase type IVA 3 is an enzyme that in humans is encoded by the PTP4A3 gene.

Delta-sarcoglycan is a protein that in humans is encoded by the SGCD gene.

Bcl-2-like protein 2 is a 193-amino acid protein that in humans is encoded by the BCL2L2 gene on chromosome 14. It was originally discovered by Leonie Gibson, Suzanne Cory and colleagues at the Walter and Eliza Hall Institute of Medical Research, who called it Bcl-w.

Receptor-type tyrosine-protein phosphatase gamma is an enzyme that in humans is encoded by the PTPRG gene.

Zinc finger protein 350 is a protein that in humans is encoded by the ZNF350 gene.

EMSY is a protein that in humans is encoded by the EMSY gene.

Zinc transporter ZIP6 is a protein that in humans is encoded by the SLC39A6 gene.

Microsomal prostaglandin E synthase-2 (mPGES-2) or Prostaglandin E synthase 2 is an enzyme that in humans encoded by the PTGES2 gene located on chromosome 9. The protein encoded by this gene is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE). Multiple transcript variants have been found for this gene.

Stromal antigen 3 is a protein that in humans is encoded by the STAG3 gene. STAG3 protein is a component of a cohesin complex that regulates the separation of sister chromatids specifically during meiosis. STAG3 appears to participate in sister-chromatid cohesion throughout the meiotic process in human oocytes.

GABA type A receptor associated protein like 1 is a protein that in humans is encoded by the GABARAPL1 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000168386 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000043336 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Filamin A interacting protein 1 like" . Retrieved 2017-09-19.

Tandle AT, Mazzanti C, Alexander HR, Roberts DD, Libutti SK (2005). "Endothelial monocyte activating polypeptide-II induced gene expression changes in endothelial cells". Cytokine. 30 (6): 347–58. doi:10.1016/j.cyto.2005.01.020. PMID 15935955.
Quaye L, Dafou D, Ramus SJ, Song H, Gentry-Maharaj A, Maharaj AG, Notaridou M, Hogdall E, Kjaer SK, Christensen L, Hogdall C, Easton DF, Jacobs I, Menon U, Pharoah PD, Gayther SA (2009). "Functional complementation studies identify candidate genes and common genetic variants associated with ovarian cancer survival". Hum. Mol. Genet. 18 (10): 1869–78. doi: 10.1093/hmg/ddp107 . PMID 19270026.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464 . PMID 20379614.
Notaridou M, Quaye L, Dafou D, Jones C, Song H, Høgdall E, Kjaer SK, Christensen L, Høgdall C, Blaakaer J, McGuire V, Wu AH, Van Den Berg DJ, Pike MC, Gentry-Maharaj A, Wozniak E, Sher T, Jacobs IJ, Tyrer J, Schildkraut JM, Moorman PG, Iversen ES, Jakubowska A, Mędrek K, Lubiński J, Ness RB, Moysich KB, Lurie G, Wilkens LR, Carney ME, Wang-Gohrke S, Doherty JA, Rossing MA, Beckmann MW, Thiel FC, Ekici AB, Chen X, Beesley J, Gronwald J, Fasching PA, Chang-Claude J, Goodman MT, Chenevix-Trench G, Berchuck A, Pearce CL, Whittemore AS, Menon U, Pharoah PD, Gayther SA, Ramus SJ (2011). "Common alleles in candidate susceptibility genes associated with risk and development of epithelial ovarian cancer". Int. J. Cancer. 128 (9): 2063–74. doi:10.1002/ijc.25554. PMC 3098608 . PMID 20635389.
Burton ER, Gaffar A, Lee SJ, Adeshuko F, Whitney KD, Chung JY, Hewitt SM, Huang GS, Goldberg GL, Libutti SK, Kwon M (2011). "Downregulation of Filamin A interacting protein 1-like is associated with promoter methylation and induces an invasive phenotype in ovarian cancer". Mol. Cancer Res. 9 (8): 1126–38. doi:10.1158/1541-7786.MCR-11-0162. PMC 3157597 . PMID 21693594.
Hu Y, Mivechi NF (2011). "Promotion of heat shock factor Hsf1 degradation via adaptor protein filamin A-interacting protein 1-like (FILIP-1L)". J. Biol. Chem. 286 (36): 31397–408. doi: 10.1074/jbc.M111.255851 . PMC 3173115 . PMID 21784850.
Revert-Ros F, López-Pascual E, Granero-Moltó F, Macías J, Breyer R, Zent R, Hudson BG, Saadeddin A, Revert F, Blasco R, Navarro C, Burks D, Saus J (2011). "Goodpasture antigen-binding protein (GPBP) directs myofibril formation: identification of intracellular downstream effector 130-kDa GPBP-interacting protein (GIP130)". J. Biol. Chem. 286 (40): 35030–43. doi: 10.1074/jbc.M111.249458 . PMC 3186396 . PMID 21832087.
Beaty TH, Taub MA, Scott AF, Murray JC, Marazita ML, Schwender H, Parker MM, Hetmanski JB, Balakrishnan P, Mansilla MA, Mangold E, Ludwig KU, Noethen MM, Rubini M, Elcioglu N, Ruczinski I (2013). "Confirming genes influencing risk to cleft lip with/without cleft palate in a case-parent trio study". Hum. Genet. 132 (7): 771–81. doi:10.1007/s00439-013-1283-6. PMC 3707506 . PMID 23512105.
Kwon M, Lee SJ, Wang Y, Rybak Y, Luna A, Reddy S, Adem A, Beaty BT, Condeelis JS, Libutti SK (2014). "Filamin A interacting protein 1-like inhibits WNT signaling and MMP expression to suppress cancer cell invasion and metastasis". Int. J. Cancer. 135 (1): 48–60. doi:10.1002/ijc.28662. PMC 3991758 . PMID 24327474.

This article on a gene on human chromosome 3 is a stub. You can help Wikipedia by expanding it.

This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000168386 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000043336 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Filamin A interacting protein 1 like" . Retrieved 2017-09-19.

[1]

[2]

[3]

[4]

[5]

Filamin A interacting protein 1 like

Related Research Articles

References

Further reading