Flavonol 3-sulfotransferase

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flavonol 3-sulfotransferase
Identifiers
EC no. 2.8.2.25
CAS no. 121855-10-5
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In enzymology, a flavonol 3-sulfotransferase (EC 2.8.2.25) is an enzyme that catalyzes the chemical reaction

3'-phosphoadenylyl sulfate + flavonol adenosine 3',5'-bisphosphate + flavonol 3-sulfate

Thus, the two substrates of this enzyme are 3'-phosphoadenylyl sulfate and a flavonol, whereas its two products are adenosine 3',5'-bisphosphate and flavonol 3-sulfate. A specific examples of a flavonol that can act as a substrate is quercetin. [1]

This enzyme belongs to the family of transferases termed the sulfotransferases, which transfer sulfate groups. The systematic name of this enzyme class is 3'-phosphoadenylyl-sulfate:flavonol 3-sulfotransferase.

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Quercetin 3-<i>O</i>-sulfate Chemical compound

Quercetin 3-sulfate is a plasma human metabolite of quercetin. It is the sulfate conjugate of quercetin.

Flaveria chlorifolia, the clasping yellowtops, is a North American plant species of Flaveria within the family Asteraceae. It is native to the southwestern United States and northern Mexico.

References

  1. Varin L, Ibrahim RK (July 1989). "Partial Purification and Characterization of Three Flavonol-Specific Sulfotransferases from Flaveria chloraefolia". Plant Physiology. 90 (3): 977–81. doi:10.1104/pp.90.3.977. PMC   1061831 . PMID   16666908.