Human Nutrition Research Center on Aging

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The Jean Mayer Human Nutrition Research Center on Aging (HNRCA), located in Boston, Massachusetts, is one of six human nutrition research centers in the United States supported by the United States Department of Agriculture Agricultural Research Service. The goal of the HNRCA, which is managed by Tufts University, is to explore the relationship between nutrition, physical activity, and healthy and active aging. [1] [2]

Contents

History

In the Food and Agriculture Act of 1977, [3] Congress directed the Secretary of Agriculture to establish a comprehensive human nutrition research program and to study the potential cost and value of regional research centers for nutrition. The Agriculture Appropriations Bill, passed later in 1977, [3] instructed the USDA to establish an "adult" human nutrition research facility at Tufts University in Massachusetts. On August 1, 1979, the Cooperative Agreement between Tufts University and the USDA was signed, and on October 23 of the same year, the National Institute on Aging and the USDA signed a Memorandum of Understanding detailing their mutual interest in the HNRCA at Tufts University. Tufts University donated land from its Boston campus for the HNRCA. It is run by cooperative agreement between the ARS and Tufts University. [4]

Contributions to society

The HNRCA is one of the largest research centers in the world studying nutrition and physical activity in healthy and active aging and the prevention of age-related disease. [5] It has made significant contributions to U.S. and international nutritional and physical activity recommendations, public policy, and clinical healthcare. [6] These contributions include advancements in the knowledge of the role of dietary calcium [7] [8] and vitamin D in promoting nutrition and bone health, [9] the role of nutrients in maintaining the optimal immune response [10] and prevention of infectious diseases, role of diet in prevention of cancer, obesity research, [11] modifications to the Food Guide Pyramid, [12] contribution to USDA nutrient data bank, advancements in the study of sarcopenia, heart disease, [13] vision, brain and cognitive function, [14] front of packaging food labeling initiatives, [15] and research of how genetic factors impact predisposition to weight gain [6] and various health indicators.

Center structure

The HNRCA employs 270 people, including 60 scientific researchers (holding degrees of Ph.D., M.D., M.P.H., D.V.M.) with faculty appointments at different schools at Tufts University, adjunct scientists, postdoctoral fellows, visiting scientists, ARS researchers, graduate students and other trainees, and administrative and scientific support staff. HNRCA scientists are trained in nutrition, biochemistry, genetics, medicine, endocrinology, gastroenterology, physiology, veterinary medicine, epidemiology, physics, and molecular biology. [16] [17]

Current research

Research clusters within the HNRCA address four specific strategic areas: 1) Cancer, 2) Cardiovascular Disease, 3) Inflammation, Immunity, and Infectious Disease and 4) Obesity. [18]

HNRCA scientists collectively average more than one high-impact scientific journal publication each business day of the year and are often cited in the media. [19] [20]

Internal core units

Essential scientific core services provided within the HNRCA are Biostatistics, [21] Comparative Biology Unit, [22] Dietary Assessment Unit, [23] Functional Genomics, [24] Mass Spectrometry, [25] Metabolic Research Unit, [26] and Nutrition Evaluation Laboratory. [27]

Research and publications

The HNRCA scientists collectively average more than one high-impact scientific journal publication each business day of the year and receive a large amount of high-profile media exposure. [28]

See also

Related Research Articles

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Vitamins are organic molecules that are essential to an organism in small quantities for proper metabolic function. Essential nutrients cannot be synthesized in the organism in sufficient quantities for survival, and therefore must be obtained through the diet. For example, vitamin C can be synthesized by some species but not by others; it is not considered a vitamin in the first instance but is in the second. Most vitamins are not single molecules, but groups of related molecules called vitamers. For example, there are eight vitamers of vitamin E: four tocopherols and four tocotrienols.

A nutrient is a substance used by an organism to survive, grow, and reproduce. The requirement for dietary nutrient intake applies to animals, plants, fungi, and protists. Nutrients can be incorporated into cells for metabolic purposes or excreted by cells to create non-cellular structures, such as hair, scales, feathers, or exoskeletons. Some nutrients can be metabolically converted to smaller molecules in the process of releasing energy, such as for carbohydrates, lipids, proteins, and fermentation products, leading to end-products of water and carbon dioxide. All organisms require water. Essential nutrients for animals are the energy sources, some of the amino acids that are combined to create proteins, a subset of fatty acids, vitamins and certain minerals. Plants require more diverse minerals absorbed through roots, plus carbon dioxide and oxygen absorbed through leaves. Fungi live on dead or living organic matter and meet nutrient needs from their host.

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<span class="mw-page-title-main">Food pyramid (nutrition)</span> Visual representation of optimal servings from basic groups

A food pyramid is a representation of the optimal number of servings to be eaten each day from each of the basic food groups. The first pyramid was published in Sweden in 1974. The 1992 pyramid introduced by the United States Department of Agriculture (USDA) was called the "Food Guide Pyramid" or "Eating Right Pyramid". It was updated in 2005 to "MyPyramid", and then it was replaced by "MyPlate" in 2011.

<span class="mw-page-title-main">Mineral (nutrient)</span> Chemical element required as an essential nutrient by organisms to perform life functions

In the context of nutrition, a mineral is a chemical element. Some "minerals" are essential for life, most are not. Minerals are one of the four groups of essential nutrients, the others of which are vitamins, essential fatty acids, and essential amino acids. The five major minerals in the human body are calcium, phosphorus, potassium, sodium, and magnesium. The remaining elements are called "trace elements". The generally accepted trace elements are iron, chlorine, cobalt, copper, zinc, manganese, molybdenum, iodine, and selenium; there is some evidence that there may be more.

<span class="mw-page-title-main">Agricultural Research Service</span> Research agency of the US Department of Agriculture

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References

  1. "Partnering with Human Nutrition Research Center on Aging". Archived from the original on 2013-05-10. Retrieved 2013-05-15.
  2. "Evidence- based research on healthy active aging through nutrition".
  3. 1 2 Rosenberg, Irwin H. (1 January 2009). "History of the USDA Human Nutrition Research Center on Aging at Tufts University". The Journal of Nutrition. 139 (1): 192–193. doi: 10.3945/jn.108.096776 . PMID   19056814.
  4. Rosenberg, Irwin (2009). "History of the USDA Human Nutrition Research Center on Aging at Tufts University". The Journal of Nutrition. 139 (1): 192–3. doi: 10.3945/jn.108.096776 . PMID   19056814.
  5. "Center Studying Diet's Links To Aging". The New York Times. December 28, 1983.
  6. 1 2 "USDA Jean Mayer Human Nutrition Research Center on Aging , Boston, Massachusetts".
  7. "Study Finds Calcium Helpful to Older Women". The New York Times. September 27, 1990.
  8. "EFFECT OF DIETARY PROTEIN SUPPLEMENTS ON CALCIUM EXCRETION IN HEALTHY OLDER MEN AND WOMEN".
  9. "EPIDEMIOLOGY, NUTRITION AND PROBLEMS OF AGING - JEAN MAYER USDA, HNRCA AT TUFTS UNIV". www.reeis.usda.gov.
  10. "Effect of Age on Susceptibility to Salmonella typhimurium Infection in C57BL/6 Mice: Role of the Immune System".
  11. "ARS National Research Program on Obesity" (PDF). Agricultural Research. March 2006.
  12. "Tufts MyPlate for Older Adults".[ dead link ]
  13. "Berry Season" (PDF). Archived from the original (PDF) on 2014-11-14. Retrieved 2013-05-15.
  14. "Neuroscience and Aging Lab - Human Nutrition Research Center on Aging". 26 September 2013. Archived from the original on 26 September 2013.
  15. "Partners : USDA ARS".
  16. "Tufts University Abridged Fact Book 2007-2008" (PDF). Office of Institutional Research & Evaluation. 2009.
  17. "Jean Mayer Human Nutrition Research Center on Aging : USDA ARS".
  18. "Research Teams".
  19. "Journal publications".
  20. "HNRCA in the media".
  21. "Biostatistics and Data Management Unit - Jean Mayer USDA Human Nutrition Research Center on Aging".
  22. "Comparative Biology Unit - Jean Mayer USDA Human Nutrition Research Center on Aging".
  23. "Dietary Assessment Unit - Jean Mayer USDA Human Nutrition Research Center on Aging".
  24. "Functional Genomics Core - Human Nutrition Research Center on Aging". 23 May 2013. Archived from the original on 23 May 2013.
  25. "Mass Spectrometry Unit - Jean Mayer USDA Human Nutrition Research Center on Aging".
  26. "Metabolic Research Unit - Jean Mayer USDA Human Nutrition Research Center on Aging".
  27. "Nutrition Evaluation Laboratory - Jean Mayer USDA Human Nutrition Research Center on Aging".
  28. "Google Scholar". scholar.google.com.

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