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Allergies, also known as allergic diseases, refer to a number of conditions caused by the hypersensitivity of the immune system to typically harmless substances in the environment. These diseases include hay fever, food allergies, atopic dermatitis, allergic asthma, and anaphylaxis. Symptoms may include red eyes, an itchy rash, sneezing, coughing, a runny nose, shortness of breath, or swelling. Note: food intolerances and food poisoning are separate conditions.
An allergen is a type of antigen that produces an abnormally vigorous immune response in which the immune system fights off a perceived threat that would otherwise be harmless to the body. Such reactions are called allergies.
Anaphylaxis is a serious, potentially fatal allergic reaction and medical emergency that is rapid in onset and requires immediate medical attention regardless of use of emergency medication on site. It typically causes more than one of the following: an itchy rash, throat closing due to swelling which can obstruct or stop breathing; severe tongue swelling which can also interfere with or stop breathing; shortness of breath, vomiting, lightheadedness, loss of consciousness, low blood pressure, and medical shock. These symptoms typically start in minutes to hours and then increase very rapidly to life-threatening levels. Urgent medical treatment is required to prevent serious harm or death, even if the patient has used an epipen or has taken other medications in response, and even if symptoms appear to be improving.
Most ants are capable of biting, stinging, and spraying irritant chemicals. However, only relatively few species can harm humans; among which some can cause significant injury or, in rare cases, death. Like wasps, individual ants are capable of stinging multiple times as they do not lose their stingers.
Fire ants are several species of ants in the genus Solenopsis, which includes over 200 species. Solenopsis are stinging ants, and most of their common names reflect this, for example, ginger ants and tropical fire ants. Many of the names shared by this genus are often used interchangeably to refer to other species of ant, such as the term red ant, mostly because of their similar coloration despite not being in the genus Solenopsis. Both Myrmica rubra and Pogonomyrmex barbatus are common examples of non-Solenopsis ants being termed red ants.
Immunoglobulin E (IgE) is a type of antibody that has been found only in mammals. IgE is synthesised by plasma cells. Monomers of IgE consist of two heavy chains and two light chains, with the ε chain containing four Ig-like constant domains (Cε1–Cε4). IgE is thought to be an important part of the immune response against infection by certain parasitic worms, including Schistosoma mansoni, Trichinella spiralis, and Fasciola hepatica. IgE is also utilized during immune defense against certain protozoan parasites such as Plasmodium falciparum. IgE may have evolved as a defense to protect against venoms.
The black imported fire ant, or simply BIFA, is a species of ant in the genus Solenopsis. It was long thought to either be a subspecies or a color variation of Solenopsis invicta, but is now recognized as its own species with a demonstratively different range and living habits. BIFA seem to be more tolerant of cold and a less dominant species than RIFA. Due to the BIFA higher body content of water than the RIFA conclusions demonstrate the certain factor plays a role in their differences of living regions.
Type I hypersensitivity, in the Gell and Coombs classification of allergic reactions, is an allergic reaction provoked by re-exposure to a specific type of antigen referred to as an allergen. Type I is distinct from type II, type III and type IV hypersensitivities. The relevance of the Gell and Coombs classification of allergic reactions has been questioned in the modern-day understanding of allergy, and it has limited utility in clinical practice.
Allergen immunotherapy, also known as desensitization or hypo-sensitization, is a medical treatment for environmental allergies, such as insect bites, and asthma. Immunotherapy involves exposing people to larger and larger amounts of allergen in an attempt to change the immune system's response.
The jack jumper ant, also known as the jack jumper, jumping jack, hopper ant, or jumper ant, is a species of venomous ant native to Australia. Most frequently found in Tasmania and southeast mainland Australia, it is a member of the genus Myrmecia, subfamily Myrmeciinae, and was formally described and named by British entomologist Frederick Smith in 1858. This species is known for its ability to jump long distances. These ants are large; workers and males are about the same size: 12 to 14 mm for workers, and 11 to 12 mm for males. The queen measures roughly 14 to 16 mm long and is similar in appearance to workers, whereas males are identifiable by their perceptibly smaller mandibles.
A bee sting is the wound and pain caused by the stinger of a female bee puncturing skin. Bee stings differ from insect bites, with the venom of stinging insects having considerable chemical variation. The reaction of a person to a bee sting may vary according to the bee species. While bee stinger venom is slightly acidic and causes only mild pain in most people, allergic reactions may occur in people with allergies to venom components.
Egg allergy is an immune hypersensitivity to proteins found in chicken eggs, and possibly goose, duck, or turkey eggs. Symptoms can be either rapid or gradual in onset. The latter can take hours to days to appear. The former may include anaphylaxis, a potentially life-threatening condition which requires treatment with epinephrine. Other presentations may include atopic dermatitis or inflammation of the esophagus.
Skeeter syndrome is a localized severe allergic reaction to mosquito bites, consisting of inflammation, peeling skin, hives, ulceration and sometimes fever. It is caused by allergenic polypeptides in mosquito saliva, and therefore is not contagious. It is one of several forms, being one of the most severe, of allergic responses to mosquito bites, termed mosquito bite allergies.
Ant venom is any of, or a mixture of, irritants and toxins inflicted by ants. Most ants spray or inject a venom, the main constituent of which is formic acid only in the case of subfamily Formicinae.
Many species of arthropods can bite or sting human beings. These bites and stings generally occur as a defense mechanism or during normal arthropod feeding. While most cases cause self-limited irritation, medically relevant complications include envenomation, allergic reactions, and transmission of vector-borne diseases.
Kounis syndrome is defined as acute coronary syndrome caused by an allergic reaction or a strong immune reaction to a drug or other substance. It is a rare syndrome with authentic cases reported in 130 males and 45 females, as reviewed in 2017; however, the disorder is suspected of being commonly overlooked and therefore much more prevalent. Mast cell activation and release of inflammatory cytokines as well as other inflammatory agents from the reaction leads to spasm of the arteries leading to the heart muscle or a plaque breaking free and blocking one or more of those arteries.
The toxicology of fire ant venom is relatively well studied. The venom plays a central role in the biology of Red imported fire ants, such as in capturing prey, and in defending itself from competitors, assailants, and diseases. Some 14 million people are stung annually in the United States, suffering reactions that vary from mild discomfort, to pustule formation, swelling, and in rare cases, systemic reactions followed by anaphylactic shock. Fire ant venoms are mainly composed (>95%) of a complex mixture of insoluble alkaloids added to a watery solution of toxic proteins. For the Red imported fire ant Solenopsis invicta Buren there are currently 46 described proteins, of which four are well-characterised as potent allergens.
Mosquito bite allergies, also termed hypersensitivity to mosquito bites, are excessive reactions of varying severity to mosquito bites.
Fish allergy is an immune hypersensitivity to proteins found in fish. Symptoms can be either rapid or gradual in onset. The latter can take hours to days to appear. The former may include anaphylaxis, a potentially life-threatening condition which requires treatment with epinephrine. Other presentations may include atopic dermatitis or inflammation of the esophagus. Fish is one of the eight common food allergens which are responsible for 90% of allergic reactions to foods: cow's milk, eggs, wheat, shellfish, peanuts, tree nuts, fish, and soy beans.
A food allergy to sesame seeds has prevalence estimates in the range of 0.1–0.2% of the general population, and are higher in the Middle East and other countries where sesame seeds are used in traditional foods. Reporting of sesame seed allergy has increased in the 21st century, either due to a true increase from exposure to more sesame foods or due to an increase in awareness. Increasing sesame allergy rates have induced more countries to regulate food labels to identify sesame ingredients in products and the potential for allergy. In the United States, sesame became the ninth food allergen with mandatory labeling, effective 1 January 2023.
References
- 1 2 Visitsunthorn, Nualanong; Kijmassuwan, Teera; Visitsunthorn, Kittipos; Pacharn, Panchama; Jirapongsananuruk, Orathai (June 2017). "Clinical Characteristics of Allergy to Hymenoptera Stings". Pediatric Emergency Care (9): 600–604. doi:10.1097/PEC.0000000000001200. ISSN 0749-5161. PMID 28614101. S2CID 24382015.
- ↑ Zamith-Miranda, Daniel; Fox, Eduardo G. P.; Monteiro, Ana Paula; Gama, Diogo; Poublan, Luiz E.; de Araujo, Almair Ferreira; Araujo, Maria F. C.; Atella, Georgia C.; Machado, Ednildo A. (December 2018). "The allergic response mediated by fire ant venom proteins". Scientific Reports. 8 (1): 14427. Bibcode:2018NatSR...814427Z. doi:10.1038/s41598-018-32327-z. ISSN 2045-2322. PMC 6158280 . PMID 30258210.
- ↑ Prahlow, Joseph; Barnard, Jeffrey (1998-06-01). "Fatal Anaphylaxis Due to Fire Ant Stings". The American Journal of Forensic Medicine and Pathology. 19 (2): 137–142. doi:10.1097/00000433-199806000-00007. ISSN 0195-7910. PMID 9662108.
- ↑ Riches, KJ; Gillis, D; James, RA (2002). "An autopsy approach to bee sting-related deaths". Pathology. 34 (3): 257–62. doi:10.1080/00313020220131327. PMID 12109787. S2CID 20615755.
- ↑ Golden DBK. Epidemiology of allergy to insect venoms and stings. Allergy Proc 1989;10:103-7
- ↑ Boyle, Robert J; Elremeli, Mariam; Hockenhull, Juliet; Cherry, Mary Gemma; Bulsara, Max K; Daniels, Michael; Oude Elberink, J.N.G. (2012-10-17). "Venom immunotherapy for preventing allergic reactions to insect stings". Cochrane Database of Systematic Reviews. 10 (2): CD008838. doi:10.1002/14651858.CD008838.pub2. ISSN 1465-1858. PMID 23076950.
- Golden DBK. Epidemiology of allergy to insect venoms and stings. Allergy Proc 1989;10:103-7