LMLN

LMLN
Identifiers
Aliases	LMLN , GP63, INV, IX14, MSP, leishmanolysin like peptidase, LMNL1
External IDs	OMIM: 609380 MGI: 2444736 HomoloGene: 13198 GeneCards: LMLN
Gene location (Human)
Chr.	Chromosome 3 (human)
End	198,043,720 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	32,948,065 bp
RNA expression pattern
	Top expressed in
	bronchial epithelial cell; ; corpus epididymis; ; secondary oocyte; ; caput epididymis; ; Brodmann area 23; ; pancreatic ductal cell; ; sperm; ; middle temporal gyrus; ; right uterine tube; ; tibia;
	Top expressed in
	otolith organ; ; utricle; ; substantia nigra; ; spermatocyte; ; trigeminal ganglion; ; ventromedial nucleus; ; cumulus cell; ; retinal pigment epithelium; ; renal corpuscle; ; supraoptic nucleus;
	More reference expression data
	n/a
Gene ontology
Molecular function	peptidase activity ; metalloendopeptidase activity ; hydrolase activity ; metallopeptidase activity ; metal ion binding ;
Cellular component	lipid droplet ; membrane ; focal adhesion ; cytoplasm ; cytosol ;
Biological process	cell cycle ; cell adhesion ; proteolysis ; cell division ;
	Sources:Amigo / QuickGO
Orthologs
	89782
	239833
	ENSG00000185621
	ENSMUSG00000022802
	Q96KR4
	Q8BMN4
	NM_001136049 ; NM_033029
	NM_172823
	NP_001129521 ; NP_149018
	NP_766411
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated March 04, 2023

Leishmanolysin-like (metallopeptidase M8 family) is a protein that in humans is encoded by the LMLN gene.^[5]

Function

This gene encodes a zinc-metallopeptidase. The encoded protein may play a role in cell migration and invasion. Studies of a similar protein in Drosophila indicate a potential role in mitotic progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009].

Related Research Articles

Epigen also known as epithelial mitogen is a protein that in humans is encoded by the EPGN gene.

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Mitotic spindle assembly checkpoint protein MAD2B is a protein that in humans is encoded by the MAD2L2 gene.

Dual specificity protein kinase TTK also known as Mps1 is an enzyme that in humans is encoded by the TTK gene.

Sperm-associated antigen 5 is a protein that in humans is encoded by the SPAG5 gene.

ZW10 interactor (Zwint-1) is a protein that in humans is encoded by the ZWINT gene.

Disintegrin and metalloproteinase domain-containing protein 2 or Beta-fertilin is an enzyme that in humans is encoded by the ADAM2 gene.

A disintegrin and metalloproteinase with thrombospondin motifs 8 is an enzyme that in humans is encoded by the ADAMTS8 gene.

Angiomotin-like protein 1 is a protein that in humans is encoded by the AMOTL1 gene.

Nasal embryonic luteinizing hormone-releasing hormone factor is a protein that in humans is encoded by the NELF gene.

Nucleolar protein 6 is a protein that in humans is encoded by the NOL6 gene.

A disintegrin and metalloproteinase with thrombospondin motifs 10 is an enzyme that in humans is encoded by the ADAMTS10 gene.

Disintegrin and metalloproteinase domain-containing protein 23 is a non-catalytic protein that in humans is encoded by the ADAM23 gene. It is a member of the ADAM family of extracellular matrix metalloproteinases.

A Disintegrin and metalloproteinase domain-containing protein 8 is an enzyme that in humans is encoded by the ADAM8 gene.

Disintegrin and metalloproteinase domain-containing protein 28 is an enzyme that in humans is encoded by the ADAM28 gene.

Zinc finger protein 330 is a protein that in humans is encoded by the ZNF330 gene.

Disintegrin and metalloproteinase domain-containing protein 11 is an enzyme that in humans is encoded by the ADAM11 gene.

Disintegrin and metalloproteinase domain-containing protein 18 is an enzyme that in humans is encoded by the ADAM18 gene.

Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 is a protein that in humans is encoded by the ASZ1 gene.

Structural maintenance of chromosomes protein 1B (SMC-1B) is a protein that in humans is encoded by the SMC1B gene. SMC-1B belongs to a family of proteins required for chromatid cohesion and DNA recombination during meiosis and mitosis. SMC1ß protein appears to participate with other cohesins REC8, STAG3 and SMC3 in sister-chromatid cohesion throughout the whole meiotic process in human oocytes.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000185621 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000022802 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Leishmanolysin-like (metallopeptidase M8 family)".

LMLN

Contents

Function

Related Research Articles

References

Further reading