Lead citrate

Last updated
Lead citrate
Lead citrate.svg
Names
IUPAC name
2-hydroxypropane-1,2,3-tricarboxylate; lead(2+); trihydrate
Other names
Lead citrate trihydrate
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.007.402 OOjs UI icon edit-ltr-progressive.svg
EC Number
  • 208-141-1
PubChem CID
  • InChI=1S/2C6H8O7.3Pb/c2*7-3(8)1-6(13,5(11)12)2-4(9)10;;;/h2*13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;/q;;3*+2/p-6
    Key: HOQPTLCRWVZIQZ-UHFFFAOYSA-H
  • C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])O.C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])O.[Pb+2].[Pb+2].[Pb+2]
  • trihydrate:C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])O.C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])O.O.O.O.[Pb+2].[Pb+2].[Pb+2]
Properties
C12H10O14Pb3
Molar mass 999.8 g·mol−1
AppearanceWhite odorless powder or crystals
Density 4.63 g/cm3
Boiling point 309.6 °C (589.3 °F; 582.8 K)
Soluble in water, slightly soluble in alcohol [1]
Hazards
GHS labelling:
GHS-pictogram-exclam.svg GHS-pictogram-silhouette.svg GHS-pictogram-pollu.svg
Danger
H302, H332, H360, H373, H410
P201, P202, P260, P261, P264, P270, P271, P273, P281, P301+P312, P304+P312, P304+P340, P308+P313, P312, P314, P330, P391, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Lead citrate is a compound of lead and citrate that is primarily used as an enhancer for heavy metal staining in electron microscopy. [2] This salt binds to osmium and uranyl acetate and enhances contrast in many cellular structures. Lead citrate is highly reactive with carbon dioxide.

Related Research Articles

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<span class="mw-page-title-main">Trisodium citrate</span> Chemical compound

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<span class="mw-page-title-main">Iron(II) sulfide</span> Chemical compound

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ATP citrate synthase (also ATP citrate lyase (ACLY)) is an enzyme that in animals represents an important step in fatty acid biosynthesis. By converting citrate to acetyl-CoA, the enzyme links carbohydrate metabolism, which yields citrate as an intermediate, with fatty acid biosynthesis, which consumes acetyl-CoA. In plants, ATP citrate lyase generates cytosolic acetyl-CoA precursors of thousands of specialized metabolites, including waxes, sterols, and polyketides.

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Ferrous citrate, also known as iron(II) citrate or iron(2+) citrate, describes coordination complexes containing citrate anions with Fe2+ formed in aqueous solution. Although a number of complexes are possible (or even likely), only one complex has been crystallized. That complex is the coordination polymer with the formula [Fe(H2O)6]2+{[Fe(C6H5O7)(H2O)]}2.2H2O, where C6H5O73- is HOC(CH2CO2)2(CO2, i.e., the triple conjugate base of citric acid wherein the three carboxylic acid groups are ionized. Ferrous citrates are all paramagnetic, reflecting the weak crystal field of the carboxylate ligands.

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<span class="mw-page-title-main">Aluminium citrate</span> Chemical compound

Aluminium citrate is a chemical compound with the chemical formula AlC
6
H
5
O
7
. This white, crystalline salt is produced by mixing aluminium chloride hexahydrate and citric acid.

Alkali citrate is an inhibitor of kidney stones. It is used to increase urine citrate levels - this prevents calcium oxalate stones by binding to calcium and inhibiting its binding to oxalate. It is also used to increase urine pH - this prevents uric acid stones and cystine stones.

References

  1. Dale Perry (April 2016). Handbook of Inorganic Compounds. CRC Press. p. 225.
  2. Arun Sharma and Archana Sharma (2014). Chromosome Techniques: Theory and Practice. Butterworth-Heinemann. p. 285.