MED30

Last updated
MED30
Identifiers
Aliases MED30 , MED30S, THRAP6, TRAP25, mediator complex subunit 30
External IDs OMIM: 610237 MGI: 1917040 HomoloGene: 12329 GeneCards: MED30
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001282986
NM_080651
NM_001363182

NM_027212

RefSeq (protein)

NP_001269915
NP_542382
NP_001350111

NP_081488

Location (UCSC) Chr 8: 117.52 – 117.54 Mb Chr 15: 52.58 – 52.59 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse
Med30
Identifiers
SymbolMed30
Pfam PF11315
InterPro IPR021019

Mediator of RNA polymerase II transcription subunit 30 is an enzyme that in humans is encoded by the MED30 gene. [5] It represents subunit Med30 of the Mediator complex and is metazoan-specific, [6] having no homologues in yeasts.

Contents

Interactions

MED30 has been shown to interact with MED22. [7]

Related Research Articles

<span class="mw-page-title-main">MED14</span> Protein-coding gene in the species Homo sapiens

Mediator of RNA polymerase II transcription subunit 14 is an enzyme that in humans is encoded by the MED14 gene.

<span class="mw-page-title-main">MED24</span> Protein-coding gene in the species Homo sapiens

Mediator of RNA polymerase II transcription subunit 24 is an enzyme that in humans is encoded by the MED24 gene.

<span class="mw-page-title-main">MED21</span> Protein-coding gene in the species Homo sapiens

Mediator of RNA polymerase II transcription subunit 21 is an enzyme that in humans is encoded by the MED21 gene.

<span class="mw-page-title-main">CRSP3</span>

Mediator of RNA polymerase II transcription subunit 23 is an enzyme that in humans is encoded by the MED23 gene.

<span class="mw-page-title-main">MED6</span> Protein-coding gene in the species Homo sapiens

Mediator of RNA polymerase II transcription subunit 6 is one of the subunits of the Mediator complex. It is an enzyme that in humans is encoded by the MED6 gene.

<span class="mw-page-title-main">MED4</span>

Mediator of RNA polymerase II transcription subunit 4 also known as mediator complex subunit 4 (MED4), a component of Mediator or vitamin D3 receptor-interacting protein complex 36 kDa component (DRIP36) is a protein that in humans is encoded by the MED4 gene.

<span class="mw-page-title-main">MED17</span>

Mediator of RNA polymerase II transcription subunit 17 is an enzyme that in humans is encoded by the MED17 gene.

<span class="mw-page-title-main">MED31</span> Protein-coding gene in the species Homo sapiens

Mediator of RNA polymerase II transcription subunit 31 is a protein in humans encoded by the MED31 gene. It represents subunit Med31 of the Mediator complex. The family contains the Saccharomyces cerevisiae SOH1 homologues. SOH1 is responsible for the repression of temperature sensitive growth of the HPR1 mutant and has been found to be a component of the RNA polymerase II transcription complex. SOH1 not only interacts with factors involved in DNA repair, but transcription as well. Thus, the SOH1 protein may serve to couple these two processes.

<span class="mw-page-title-main">MED22</span> Protein-coding gene in the species Homo sapiens

Mediator of RNA polymerase II transcription subunit 22 is an enzyme that in humans is encoded by the MED22 gene.

<span class="mw-page-title-main">MED7</span>

Mediator of RNA polymerase II transcription subunit 7 is an enzyme that in humans is encoded by the MED7 gene.

<span class="mw-page-title-main">USP47</span>

Ubiquitin carboxyl-terminal hydrolase 47 is an enzyme that in humans is encoded by the USP47 gene.

<span class="mw-page-title-main">MED28</span>

Mediator of RNA polymerase II transcription subunit 28 is an enzyme that in humans is encoded by the MED28 gene. It forms part of the Mediator complex.

<span class="mw-page-title-main">MED25</span> Protein-coding gene in the species Homo sapiens

Mediator of RNA polymerase II transcription subunit 25 is an enzyme that in humans is encoded by the MED25 gene.

<span class="mw-page-title-main">MED8</span> Protein-coding gene in the species Homo sapiens

Mediator of RNA polymerase II transcription subunit 8 is an enzyme that in humans is encoded by the MED8 gene.

<span class="mw-page-title-main">MED27</span> Protein-coding gene in the species Homo sapiens

Mediator of RNA polymerase II transcription subunit 27 is an enzyme that in humans is encoded by the MED27 gene. It forms part of the Mediator complex.

<span class="mw-page-title-main">MED16</span> Protein-coding gene in the species Homo sapiens

Mediator of RNA polymerase II transcription subunit 16 is an enzyme that in humans is encoded by the MED16 gene.

<span class="mw-page-title-main">MED26</span> Protein-coding gene in the species Homo sapiens

Mediator of RNA polymerase II transcription subunit 26 is an enzyme that in humans is encoded by the MED26 gene. It forms part of the Mediator complex.

<span class="mw-page-title-main">MED10</span>

Mediator complex subunit 10 (Med10) is a protein that in humans is encoded by the MED10 gene.

<span class="mw-page-title-main">MED11</span> Protein-coding gene in the species Homo sapiens

Mediator complex subunit 11 (Med11) is a protein that in humans is encoded by the MED11 gene.

<span class="mw-page-title-main">MED18</span> Protein-coding gene in the species Homo sapiens

Mediator complex subunit 18 (Med18) is a protein that in humans is encoded by the MED18 gene.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000164758 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000038622 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: THRAP6 thyroid hormone receptor associated protein 6".
  6. Baek HJ, Malik S, Qin J, Roeder RG (April 2002). "Requirement of TRAP/mediator for both activator-independent and activator-dependent transcription in conjunction with TFIID-associated TAF(II)s". Molecular and Cellular Biology. 22 (8): 2842–52. doi:10.1128/MCB.22.8.2842-2852.2002. PMC   133729 . PMID   11909976.
  7. Sato S, Tomomori-Sato C, Banks CA, Sorokina I, Parmely TJ, Kong SE, et al. (April 2003). "Identification of mammalian Mediator subunits with similarities to yeast Mediator subunits Srb5, Srb6, Med11, and Rox3". The Journal of Biological Chemistry. 278 (17): 15123–7. doi: 10.1074/jbc.C300054200 . PMID   12584197.

Further reading

This article incorporates text from the public domain Pfam and InterPro: IPR021019