MED9

MED9
Identifiers
Aliases	MED9 , MED25, mediator complex subunit 9
External IDs	OMIM: 609878 MGI: 2183151 HomoloGene: 32385 GeneCards: MED9
Gene location (Human)
Chr.	Chromosome 17 (human)
End	17,493,221 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	59,853,031 bp
RNA expression pattern
	Top expressed in
	left ventricle; ; gastrocnemius muscle; ; nucleus accumbens; ; caudate nucleus; ; Brodmann area 9; ; prefrontal cortex; ; putamen; ; amygdala; ; right lobe of liver; ; right lobe of thyroid gland;
	Top expressed in
	seminiferous tubule; ; internal carotid artery; ; yolk sac; ; external carotid artery; ; mirror; ; somite; ; atrium; ; dermis; ; endocardial cushion; ; brown adipose tissue;
	More reference expression data
	n/a
Gene ontology
Molecular function	transcription coregulator activity ; protein binding ;
Cellular component	mediator complex ; nucleus ;
Biological process	regulation of transcription by RNA polymerase II ; regulation of transcription, DNA-templated ; transcription, DNA-templated ;
	Sources:Amigo / QuickGO
Orthologs
	55090
	192191
	ENSG00000141026
	ENSMUSG00000061650
	Q9NWA0
	Q8VCS6
	NM_018019
	NM_138675
	NP_060489
	NP_619616
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated October 14, 2022

Mediator complex subunit 9 (Med9) is a protein that in humans is encoded by the MED9 gene. ^[5]

Function

The multiprotein Mediator complex is a coactivator required for activation of RNA polymerase II transcription by DNA bound transcription factors. The protein encoded by this gene is thought to be a subunit of the Mediator complex. This gene is located within the Smith–Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008].

Related Research Articles

Mediator of RNA polymerase II transcription subunit 7 is an enzyme that in humans is encoded by the MED7 gene.

V-type proton ATPase subunit C 2 is an enzyme that in humans is encoded by the ATP6V1C2 gene.

Cohesin subunit SA-1 (SA1) is a protein that in humans is encoded by the STAG1 gene. SA1 is a subunit of the Cohesin complex which mediates sister chromatid cohesion, homologous recombination and DNA looping. In somatic cells cohesin is formed of SMC3, SMC1, RAD21 and either SA1 or SA2 whereas in meiosis, cohesin is formed of SMC3, SMC1B, REC8 and SA3.

Voltage-dependent calcium channel subunit alpha2delta-2 is a protein that in humans is encoded by the CACNA2D2 gene.

Gap junction beta-5 protein (GJB5), also known as connexin-31.1 (Cx31.1), is a protein that in humans is encoded by the GJB5 gene.

Arginine and glutamate-rich protein 1 is a protein that in humans is encoded by the ARGLU1 gene located at 13q33.3.

Mediator complex subunit 13 is a protein that in humans is encoded by the MED13 gene.

Polymerase (DNA-directed), epsilon 4, accessory subunit is a protein that in humans is encoded by the POLE4 gene.

Integrator complex subunit 1 is a protein that in humans is encoded by the INTS1 gene.

INO80 complex subunit B is a protein that in humans is encoded by the INO80B gene.

Integrator complex subunit 5 is a protein that in humans is encoded by the INTS5 gene.

Transcription factor 15 is a protein that in humans is encoded by the TCF15 gene.

Nuclear export mediator factor (NEMF) is a protein that in humans is encoded by the NEMF gene.

Mediator complex subunit 10 (Med10) is a protein that in humans is encoded by the MED10 gene.

Mediator complex subunit 11 (Med11) is a protein that in humans is encoded by the MED11 gene.

Mediator complex subunit 18 (Med18) is a protein that in humans is encoded by the MED18 gene.

Mediator complex subunit 19 (Med19) is a protein that in humans is encoded by the MED19 gene.

Mediator complex subunit 12 like (Med12L) is a protein that in humans is encoded by the MED12L gene.

CCR4-NOT transcription complex subunit 10 is a protein that in humans is encoded by the CNOT10 gene. It is a subunit of the CCR4-Not deadenylase complex.

CCR4-NOT transcription complex subunit 11 is a protein that in humans is encoded by the CNOT11 gene. It is a subunit of the CCR4-Not deadenylase complex.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000141026 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000061650 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Mediator complex subunit 9" . Retrieved 2018-02-06.

MED9

Contents

Function

See also

Related Research Articles

References

Further reading