MRCL3

MYL12A
Identifiers
Aliases	MYL12A , HEL-S-24, MLCB, MRCL3, MRLC3, MYL2B, MLC-2B, myosin light chain 12A
External IDs	MGI: 107494 HomoloGene: 23407 GeneCards: MYL12A
Gene location (Human)
Chr.	Chromosome 18 (human)
End	3,256,236 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	71,297,885 bp
RNA expression pattern
	Top expressed in
	monocyte; ; right lung; ; upper lobe of left lung; ; right coronary artery; ; ascending aorta; ; left coronary artery; ; rectum; ; gallbladder; ; gastrocnemius muscle; ; appendix;
	Top expressed in
	superior frontal gyrus; ; yolk sac; ; lip; ; morula; ; mirror; ; cerebellar cortex; ; neural tube; ; proximal tubule; ; thymus; ; esophagus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	calcium ion binding ; protein binding ; metal ion binding ; myosin heavy chain binding ;
Cellular component	cytosol ; extracellular exosome ; myosin complex ; myosin II complex ; apical part of cell ; Z disc ; brush border ; stress fiber ; cell cortex region ;
Biological process	ephrin receptor signaling pathway ; muscle contraction ; platelet aggregation ; regulation of cell shape ;
	Sources:Amigo / QuickGO
Orthologs
	10627
	67938
	ENSG00000101608
	ENSMUSG00000034868
	P19105 ; O14950
	Q3THE2
	NM_001303047 ; NM_001303048 ; NM_001303049 ; NM_006471
	NM_023402
NP_001289976 ; NP_001289977 ; NP_001289978 ; NP_006462 ; NP_001138416 ;
	NP_001138417 ; NP_291024 ; NP_001289976 ; NP_001289977 ; NP_001289978 ; NP_006462 Contents See also ; References ; Further reading ;
	NP_075891
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated October 02, 2023

Myosin regulatory light chain 12A is a protein that in humans is encoded by the MYL12A gene.^[5]^[6]

Related Research Articles

Myosin regulatory light polypeptide 9 is a protein that in humans is encoded by the MYL9 gene.

Cytoplasmic dynein 1 intermediate chain 2 is a protein that in humans is encoded by the DYNC1I2 gene.

60S ribosomal protein L18a is a protein that in humans is encoded by the RPL18A gene.

CDK5 regulatory subunit-associated protein 3 is a protein that in humans is encoded by the CDK5RAP3 gene.

Dolichyl-diphosphooligosaccharide—protein glycosyltransferase subunit 1 is an enzyme that in humans is encoded by the RPN1 gene.

Myosin-14 is a protein that in humans is encoded by the MYH14 gene.

Phospholipase A-2-activating protein is an enzyme that in humans is encoded by the PLAA gene.

AP-3 complex subunit sigma-2 is a protein that in humans is encoded by the AP3S2 gene.

Myosin light chain 3, skeletal muscle isoform is a protein that in humans is encoded by the MYL1 gene.

Protein phosphatase 1 regulatory subunit 12B is an enzyme that in humans is encoded by the PPP1R12B gene.

Neurabin-1 is a protein that in humans is encoded by the PPP1R9A gene.

Tubulin gamma-2 chain is a protein that in humans is encoded by the TUBG2 gene.

Myosin light polypeptide 6 is a protein that in humans is encoded by the MYL6 gene.

Myosin regulatory light chain interacting protein, also known as MYLIP, is a protein that in humans is encoded by the MYLIP gene.

Zinc finger protein 330 is a protein that in humans is encoded by the ZNF330 gene.

Myosin light chain kinase, smooth muscle also known as kinase-related protein (KRP) or telokin is an enzyme that in humans is encoded by the MYLK gene.

Keratin, type I cytoskeletal 23 is a protein that in humans is encoded by the KRT23 gene.

RPA-interacting protein is a protein that in humans is encoded by the RPAIN gene.

Myosin light chain 6B is a protein that in humans is encoded by the MYL6B gene. Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain expressed in both slow-twitch skeletal muscle and in nonmuscle tissue.

Myosin light chain kinase 3 also known as MYLK3, is an enzyme which in humans is encoded by the MYLK3 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000101608 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000034868 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Grant JW, Zhong RQ, McEwen PM, Church SL (Nov 1990). "Human nonsarcomeric 20,000 Da myosin regulatory light chain cDNA". Nucleic Acids Res. 18 (19): 5892. doi:10.1093/nar/18.19.5892. PMC 332341 . PMID 2216787.
↑ "Entrez Gene: MRCL3 myosin regulatory light chain MRCL3".

Kobayashi K, Xin Y, Ymer SI, et al. (2007). "Subtractive hybridisation screen identifies genes regulated by glucose deprivation in human neuroblastoma cells". Brain Res. 1170: 129–39. doi:10.1016/j.brainres.2007.07.042. PMID 17719568. S2CID 31320196.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948 . PMID 17353931.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Bouwmeester T, Bauch A, Ruffner H, et al. (2004). "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway". Nat. Cell Biol. 6 (2): 97–105. doi:10.1038/ncb1086. PMID 14743216. S2CID 11683986.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Iwasaki T, Murata-Hori M, Ishitobi S, Hosoya H (2002). "Diphosphorylated MRLC is required for organization of stress fibers in interphase cells and the contractile ring in dividing cells". Cell Struct. Funct. 26 (6): 677–83. doi: 10.1247/csf.26.677 . PMID 11942626.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.

This article on a gene on human chromosome 18 is a stub. You can help Wikipedia by expanding it.

This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000101608 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000034868 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid2216787-5] Grant JW, Zhong RQ, McEwen PM, Church SL (Nov 1990). "Human nonsarcomeric 20,000 Da myosin regulatory light chain cDNA". Nucleic Acids Res. 18 (19): 5892. doi:10.1093/nar/18.19.5892. PMC 332341 . PMID 2216787.

[entrez-6] "Entrez Gene: MRCL3 myosin regulatory light chain MRCL3".

[1]

[2]

[3]

[4]

[5]

[6]

MRCL3

Contents

See also

Related Research Articles

References

Further reading