Mass spectrometry at Swansea

Last updated

Swansea University has had a long established history of development and innovation in mass spectrometry and chromatography.

Contents

Mass Spectrometry Research Unit

In 1975, John H. Beynon was appointed the Royal Society Research Professor and established the Mass Spectrometry Research Unit at Swansea University (at that time known as the University College of Swansea). [1] In 1986, Dai Games moved from Cardiff University to become the Units new Director. [2]

Director of Mass Spectrometry Research Unit
1975–19861986–20032003–2016
John BeynonDai GamesGarteh Brenton

In 1984, the first observation of He22+ was made at the unit, its the same as molecular hydrogen (isolectronic molecules) except it has lots more energy 3310 kJ per mole. [3]

National Mass Spectrometry Service

A grant of £670,000 was awarded in 1985 by the then Science and Engineering Research Council (SERC) to establish a national Mass Spectrometry Center at Swansea University to provide an analytical service to British Universities. It was officially opened in April 1987 by Lord Callaghan. In 2002, the center was enlarged and the new laboratories were opened by Lord Morgan. Following successful £3,000,000 contract renewal Edwina Hart, the Minister for Economy, Science and Transport, officially re-opened the EPSRC National Research Facility after refurbishment in 2015. [4] [5]

Director EPSRC National Mass Spectrometry Service
1986––20032003–20162016–2018
James A Ballantine Dai GamesGareth BrentonSteven Kelly
Manager of EPSRC National Mass Spectrometry Service
–2018
Bridgit SteinChristopher Williams

Biomolecular Analysis Mass Spectrometry

A Biomolecular Analysis Mass Spectrometry (BAMS) facility was officially opened in 2003, headed by Professor Newton and Dr Dudley. It was a collaborative entity between the Department of Biological Sciences and the Medical School. It focused on the study of nucleosides, nucleotides and cyclic nucleotides. [6]

Stable isotope mass spectrometry

Stable isotope mass spectrometry is conducted in the Department of Geography, and was recently used by the Landmark Trust to determine very precisely the age of the timber from Llwyn Celyn farmhouse to the year 1420. [7]

Related Research Articles

<span class="mw-page-title-main">National High Magnetic Field Laboratory</span> Magnetism research institute in the United States

The National High Magnetic Field Laboratory (MagLab) is a facility at Florida State University, the University of Florida, and Los Alamos National Laboratory in New Mexico, that performs magnetic field research in physics, biology, bioengineering, chemistry, geochemistry, biochemistry. It is the only such facility in the US, and is among twelve high magnetic facilities worldwide. The lab is supported by the National Science Foundation and the state of Florida, and works in collaboration with private industry.

The Engineering and Physical Sciences Research Council (EPSRC) is a British Research Council that provides government funding for grants to undertake research and postgraduate degrees in engineering and the physical sciences, mainly to universities in the United Kingdom. EPSRC research areas include mathematics, physics, chemistry, artificial intelligence and computer science, but exclude particle physics, nuclear physics, space science and astronomy. Since 2018 it has been part of UK Research and Innovation, which is funded through the Department for Business, Energy and Industrial Strategy.

The Doctor of Engineering, or Engineering Doctorate, is a degree awarded on the basis of advanced study and research in engineering and applied science for solving problems in industry. According to the National Science Foundation in the United States, it is a terminal research doctorate. A DEng/EngD is equivalent to a PhD in engineering, but different in that it has a solid industrial base and an additional taught element. The degree is usually aimed toward working professionals.

Gary J Van Berkel, born in 1959, is the research scientist who led the Organic and Biological Mass Spectrometry Group at Oak Ridge National Laboratory until his retirement from there in 2018. He is currently owner and CSO of Van Berkel Ventures, LLC, an analytical measurement science, innovation, research, consulting and writing firm in Oak Ridge, TN.

<span class="mw-page-title-main">Mass-analyzed ion-kinetic-energy spectrometry</span>

Mass-analyzed ion kinetic-energy spectrometry (MIKES) is a mass spectrometry technique by which mass spectra are obtained from a sector instrument that incorporates at least one magnetic sector plus one electric sector in reverse geometry. The accelerating voltage V, and the magnetic field B, are set to select the precursor ions of a particular m/z. The precursor ions then dissociate or react in an electric field-free region between the two sectors. The ratio of the kinetic energy to charge of the product ions are analyzed by scanning the electric sector field E. The width of the product ion spectrum peaks is related to the kinetic energy release distribution for the dissociation process.

<span class="mw-page-title-main">Swansea University Medical School</span> Medical school in Wales

Swansea University Medical School is a medical school on Swansea University's Singleton campus. It is linked to additional teaching centres located throughout South and West Wales, including Cefn Coed Hospital, Singleton Hospital and Morriston Hospital in Swansea, Prince Philip Hospital in Llanelli, Withybush General Hospital in Haverfordwest and Bronglais Hospital in Aberystwyth. The Medical School also has a network of primary care teaching centers.

Dame Carol Vivien Robinson, is a British chemist and former President of the Royal Society of Chemistry (2018–2020). She was a Royal Society Research Professor and is the Dr Lee's Professor of Physical and Theoretical Chemistry, and a Professorial Fellow at Exeter College, University of Oxford. She is the first director of the Kavli Institution for Nanoscience Discovery, University of Oxford, and she was previously Professor of Mass Spectrometry at the Department of Chemistry of the University of Cambridge.

The National Wind Tunnel Facility (NWTF), is an initiative in which 17 wind tunnels distributed across seven UK universities are made open access to external researchers in the UK and abroad, from both university and industry based.

<span class="mw-page-title-main">Michael Barber (chemist)</span> British chemist and mass spectrometrist

Michael (Mickey) Barber, FRS was a British chemist and mass spectrometrist, best known for his invention of fast atom bombardment ionisation.

The Aston Medal is awarded by the British Mass Spectrometry Society to individuals who have worked in the United Kingdom and have made outstanding contributions to our understanding of the biological, chemical, engineering, mathematical, medical, or physical sciences relating directly to mass spectrometry. The medal is named after one of Britain's founders of mass spectrometry and 1922 Nobel prize winner Francis William Aston.

The British Mass Spectrometry Society is a registered charity founded in 1964 that encourages participation in every aspect of mass spectrometry. It aims to encourage participation in all aspects of mass spectrometry on the widest basis, to promote knowledge and advancement in the field and to provide a forum for the exchange of views and information. It is committed to ensuring equal opportunities and reflecting the diversity of the society as a whole. The first foundations of the BMSS were laid in 1949 with the establishment of the Mass Spectrometry Panel by the Hydrocarbon Research Group.

<span class="mw-page-title-main">John H. Beynon</span> Welsh chemist and physicist

John H. Beynon FRS was a Welsh chemist and physicist known for his work in mass spectrometry.

<span class="mw-page-title-main">Henry Royce Institute</span> UK national institute for materials research

The Henry Royce Institute is the UK’s national institute for advanced materials research and innovation. Its vision is to identify challenges and to stimulate innovation in advanced materials research to support sustainable growth and development. Royce aims to be a "single front door" to the UK’s materials research community. Its stated mission is to “support world-recognised excellence in UK materials research, accelerating commercial exploitation of innovations, and delivering positive economic and societal impact for the UK.”

Perdita Elizabeth Barran is a Professor of Mass Spectrometry at the University of Manchester. She is Director of the Michael Barber Centre for Collaborative Mass Spectrometry. She develops and applies ion-mobility spectrometry–mass spectrometry to the study of molecule structure and is searching for biomarkers for Parkinson's disease. She is Associate Dean for Research Facility Development at the University of Manchester. In 2020 and 2021 she was seconded to work for the Department of Health and Social Care as an advisor on the use case for mass spectrometry as a diagnostic method for diagnosis of COVID infection.

A. Gareth Brenton FLSW. is a Welsh physicist and chemist known for his work in mass spectrometry.

David Edgar Games was a Welsh chemist best known for his work in mass spectrometry and chromatography.

Richard M. Caprioli is an American chemist known for his contributions to mass spectrometry imaging.

<span class="mw-page-title-main">Julia Laskin</span> Russian–American Chemist

Julia Laskin is the William F. and Patty J. Miller Professor of Analytical Chemistry at Purdue University. Her research is focused on the fundamental understanding of ion-surface collisions, understanding of phenomena underlying chemical analysis of large molecules in complex heterogeneous environments, and the development of new instrumentation and methods in preparative and imaging mass spectrometry.

Helen Jill Cooper is a British chemist who is Professor of mass spectrometry at the University of Birmingham. She serves as Deputy Head of the School of Chemistry and holds an Engineering and Physical Sciences Research Council Established Career Fellowship. Her research considers the development of native ambient mass spectrometry to enable direct analysis of intact proteins and protein assemblies from tissue.

References

  1. Cooks, Graham (April 2016). "John H. Beynon (1923–2015)". Journal of the American Society for Mass Spectrometry. 27 (4): 561–562. Bibcode:2016JASMS..27..561C. doi:10.1007/s13361-016-1337-9. ISSN   1044-0305. PMID   26832345. S2CID   34383141.
  2. Jones, Jonathan J. (September 2020). "Remembering Dai Games". Rapid Communications in Mass Spectrometry. 34 (S4): e8889. doi: 10.1002/rcm.8889 . ISSN   0951-4198. PMID   32657448.
  3. Guilhaus, M; Brenton, A G; Beynon, J H; Rabrenovic, M; Schleyer, P Von Rague (1984-09-14). "First observation of He 2 2+ : charge stripping of He 2 + using a double-focusing mass spectrometer". Journal of Physics B: Atomic and Molecular Physics. 17 (17): L605–L610. Bibcode:1984JPhB...17L.605G. doi:10.1088/0022-3700/17/17/010. ISSN   0022-3700.
  4. "Science Minister opens National Mass Spectrometry Facility after £3m contract renewal and facility refurbishment". www-2018.swansea.ac.uk. Retrieved 2021-04-13.
  5. "National Research Facilities - EPSRC website". epsrc.ukri.org. Retrieved 2021-04-13.
  6. "Breakthrough cover" (PDF). Retrieved 13 April 2020.{{cite web}}: CS1 maint: url-status (link)
  7. "Welsh farmstead is rare medieval hall house, experts confirm". the Guardian. 2019-01-13. Retrieved 2021-04-13.