NINJ1

NINJ1
Identifiers
Aliases	NINJ1 , NIN1, NINJURIN, ninjurin 1
External IDs	OMIM: 602062 MGI: 1196617 HomoloGene: 88815 GeneCards: NINJ1
Gene location (Human)
Chr.	Chromosome 9 (human)
End	93,134,251 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	49,349,720 bp
RNA expression pattern
	Top expressed in
	Left adrenal gland; ; monocyte; ; thoracic aorta; ; ascending aorta; ; right lobe of liver; ; blood; ; gastric mucosa; ; left lobe of thyroid gland; ; right coronary artery; ; skin of abdomen;
	Top expressed in
	pyloric antrum; ; left lobe of liver; ; facial motor nucleus; ; calvaria; ; utricle; ; secondary oocyte; ; proximal tubule; ; islet of Langerhans; ; kidney; ; parotid gland;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding ;
Cellular component	integral component of membrane ; membrane ;
Biological process	hyaloid vascular plexus regression ; cell adhesion ; nervous system development ; tissue regeneration ; positive regulation of cell-matrix adhesion ; pyroptosis ; cell death ;
	Sources:Amigo / QuickGO
Orthologs
	4814
	18081
	ENSG00000131669
	ENSMUSG00000037966
	Q92982
	O70131
	NM_004148
	NM_013610
	NP_004139
	NP_038638
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated October 14, 2022

Ninjurin-1 is a protein that in humans is encoded by the NINJ1 gene.^[5]^[6]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000131669 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000037966 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Araki T, Milbrandt J (Oct 1996). "Ninjurin, a novel adhesion molecule, is induced by nerve injury and promotes axonal growth". Neuron. 17 (2): 353–61. doi: 10.1016/S0896-6273(00)80166-X . PMID 8780658. S2CID 12471778.
↑ "Entrez Gene: NINJ1 ninjurin 1".

Guimarães PE, Fridman C, Gregório SP, et al. (2007). "WITHDRAWN: Association between polymorphisms in genes of inflammatory response and axonal repair with spinal cord injury". Spinal Cord. doi:10.1038/sj.sc.3102122. PMID 17893696.
Cardoso CC, Martinez AN, Guimarães PE, et al. (2007). "Ninjurin 1 asp110ala single nucleotide polymorphism is associated with protection in leprosy nerve damage". J. Neuroimmunol. 190 (1–2): 131–8. doi:10.1016/j.jneuroim.2007.07.015. PMID 17825431. S2CID 20637695.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Toyama T, Sasaki Y, Horimoto M, et al. (2005). "Ninjurin1 increases p21 expression and induces cellular senescence in human hepatoma cells". J. Hepatol. 41 (4): 637–43. doi:10.1016/j.jhep.2004.06.027. PMID 15464245.
Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. Bibcode:2004Natur.429..369H. doi:10.1038/nature02465. PMC 2734081 . PMID 15164053.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Chadwick BP, Heath SK, Williamson J, et al. (1998). "The human homologue of the ninjurin gene maps to the candidate region of hereditary sensory neuropathy type I (HSNI)". Genomics. 47 (1): 58–63. doi:10.1006/geno.1997.5084. PMID 9465296.
Araki T, Zimonjic DB, Popescu NC, Milbrandt J (1997). "Mechanism of homophilic binding mediated by ninjurin, a novel widely expressed adhesion molecule". J. Biol. Chem. 272 (34): 21373–80. doi: 10.1074/jbc.272.34.21373 . PMID 9261151.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000131669 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000037966 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8780658-5] Araki T, Milbrandt J (Oct 1996). "Ninjurin, a novel adhesion molecule, is induced by nerve injury and promotes axonal growth". Neuron. 17 (2): 353–61. doi: 10.1016/S0896-6273(00)80166-X . PMID 8780658. S2CID 12471778.

[entrez-6] "Entrez Gene: NINJ1 ninjurin 1".

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NINJ1

Related Research Articles

References

Further reading