Nancy Allbritton

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Nancy Allbritton
Nancy Allbritton.jpg
NationalityAmerican
Alma mater Louisiana State University (BS)
Johns Hopkins University (MD)
Massachusetts Institute of Technology (PhD)
Known forSingle-cell analysis
Scientific career
FieldsBiomedical Engineering
Institutions University of Washington University of North Carolina at Chapel Hill and North Carolina State University

Nancy Allbritton is a Professor of Bioengineering and the Frank & Julie Jungers Dean of the College of Engineering at the University of Washington. [1] She was previously a Kenan Professor and Chair in the Joint Department of Biomedical Engineering at the University of North Carolina at Chapel Hill and North Carolina State University. [2]

Contents

She is best known for her work in single-cell analysis. Using engineering methods, Allbritton creates tools for better understanding and manipulating living cells and tissues. Microengineered platforms, microfluidics, and novel biochemical assays enable scientists to study cell signaling and signal transduction at the single-cell level. [3]

Education

Allbritton received a bachelor of science with a major in physics from Louisiana State University, Baton Rouge in 1979. She received a doctor of medicine from Johns Hopkins University in 1985 and a doctor of philosophy in medical physics and medical engineering from the Massachusetts Institute of Technology in 1987. [4]

Career

Allbritton was a postdoctoral fellow at Stanford University from 1989 to 1994. [5] She then became a Professor at the University of California at Irvine, teaching in the departments of Physiology and Biophysics, Biomedical Engineering, Chemistry, Chemical Engineering and Materials Science. She remained at UC Irvine for 13 years, from 1994-2007. [5]

In 2007 Allbritton joined the University of North Carolina at Chapel Hill, becoming a Kenan Distinguished Professor. From 2009-2019 she was the Chair of the Joint Department of Biomedical Engineering at the University of North Carolina at Chapel Hill and North Carolina State University. [2] She has held faculty appointments in Chemistry, Pharmacology and Applied Physical Sciences at UNC, and in the Department of Materials Science and Engineering at NC State. [6]

As of November 1, 2019, Allbritton became a Professor of Bioengineering and the Frank & Julie Jungers Dean of Engineering at the University of Washington College of Engineering. [7] [1]

Allbritton was appointed a co-editor of the Annual Review of Analytical Chemistry in 2021. [8]

Research interests

Allbritton's interest in single-cell analysis have hinged on the use of capillary electrophoresis (CE) and microfabricated technologies. Through this work she has studied lipid signaling at the single-cell level, the isolation cytotoxic t-cells with specific properties, and the capture of colonic crypts. In the organ-on-a-chip field, [9] Allbritton has used fabrication technologies from electronics and microfluidics to develop devices that effectively recreate the environment of both the small and large intestine. [10] [11] These include micro total analysis systems [12] [13] and microraft arrays. [14] In the area of dielectrophoresis (DEP), Allbritton's lab works on the transfer of DEP-based systems out of laboratories and into clinical use. [15]

Awards

Patents

Related Research Articles

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References

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  2. 1 2 "Meet the Team | Single-Cell Isolation and Recovery". Cellmicrosystems.com. Retrieved 2017-05-01.
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  10. Landhuis, Esther (26 September 2019). "Microbial chemistry gains fresh focus". Nature. 573 (7775): 615–616. Bibcode:2019Natur.573..615L. doi: 10.1038/d41586-019-02853-5 . PMID   31551561.
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  13. Kovarik, Michelle L.; Ornoff, Douglas M.; Melvin, Adam T.; Dobes, Nicholas C.; Wang, Yuli; Dickinson, Alexandra J.; Gach, Philip C.; Shah, Pavak K.; Allbritton, Nancy L. (15 January 2013). "Micro Total Analysis Systems: Fundamental Advances and Applications in the Laboratory, Clinic, and Field". Analytical Chemistry. 85 (2): 451–472. doi:10.1021/ac3031543. PMC   3546124 . PMID   23140554.
  14. Smiddy, Nicole M.; DiSalvo, Matthew; Allbritton-King, Jules D.; Allbritton, Nancy L. (2020). "Microraft array-based platform for sorting of viable microcolonies based on cell-lethal immunoassay of intracellular proteins in microcolony biopsies". The Analyst. 145 (7): 2649–2660. Bibcode:2020Ana...145.2649S. doi:10.1039/D0AN00030B. PMC   7117799 . PMID   32048684.
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