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| Identifiers | |
|---|---|
3D model (JSmol) | |
| ChemSpider | |
PubChem CID | |
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| Properties | |
| C20H30O3 | |
| Molar mass | 318.457 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
Neotripterifordin is an anti-viral diterpene lactone isolated from Tripterygium wilfordii . [1]
This gallery of sovereign state flags shows the national or state flags of sovereign states that appear on the list of sovereign states. For flags of other entities, please see gallery of flags of dependent territories. Each flag is depicted as if the flagpole is positioned on the left of the flag, except for those of Iran, Iraq and Saudi Arabia which are depicted with the hoist to the right.
In mathematics the spin group, denoted Spin(n), is a Lie group whose underlying manifold is the double cover of the special orthogonal group SO(n) = SO(n, R), such that there exists a short exact sequence of Lie groups (when n ≠ 2)
The Celastraceae are a family of 98 genera and 1,350 species of herbs, vines, shrubs and small trees, belonging to the order Celastrales. The great majority of the genera are tropical, with only Celastrus, Euonymus and Maytenus widespread in temperate climates, and Parnassia (bog-stars) found in alpine and arctic climates.
Tripterygium wilfordii, or léi gōng téng (Mandarin), sometimes called thunder god vine but more properly translated thunder duke vine, is a vine used in traditional Chinese medicine.
Oat sensitivity represents a sensitivity to the proteins found in oats, Avena sativa. Sensitivity to oats can manifest as a result of allergy to oat seed storage proteins either inhaled or ingested. A more complex condition affects individuals who have gluten-sensitive enteropathy in which there is an autoimmune response to avenin, the glutinous protein in oats similar to the gluten within wheat. Sensitivity to oat foods can also result from their frequent contamination by wheat, barley, or rye particles.
A quinone methide is a type of conjugated organic compound that contain a cyclohexadiene with a carbonyl and an exocyclic methylidene or extended alkene unit. It is analogous to a quinone, but having one of the double bonded oxygens replaced with a carbon. The carbonyl and methylidene are usually oriented either ortho or para to each other. There are some examples of transient synthetic meta quinone methides.
Triptolide is a diterpenoid epoxide which is produced by the thunder god vine, Tripterygium wilfordii. It has in vitro and in vivo activities against mouse models of polycystic kidney disease and pancreatic cancer, but its physical properties and severe toxicity limit its therapeutic potential. Consequently, a synthetic water-soluble prodrug, minnelide, is being studied clinically instead.
Celastrol (tripterine) is a chemical compound isolated from the root extracts of Tripterygium wilfordii and Tripterygium regelii. Celastrol is a pentacyclic nortriterpen quinone and belongs to the family of quinone methides. In mice, celastrol is an NR4A1 agonist that alleviates inflammation and induces autophagy. Also in mice, celastrol increase expression of IL1R1, which is the receptor for the cytokine interleukin-1 (IL-1). IL1R1 knock-out mice exposed to celastrol exhibit no leptin-sensitizing or anti-obesity effect.
The 3C-like protease (3CLpro) or main protease (Mpro), formally known as C30 endopeptidase or 3-chymotrypsin-like protease, is the main protease found in coronaviruses. It cleaves the coronavirus polyprotein at eleven conserved sites. It is a cysteine protease and a member of the PA clan of proteases. It has a cysteine-histidine catalytic dyad at its active site and cleaves a Gln–(Ser/Ala/Gly) peptide bond.
Triptofordin C-2 is an antiviral chemical compound isolated from Tripterygium wilfordii.
Tripchlorolide is an isolate of Tripterygium wilfordii (雷公藤) that has potential interaction with the NMDA receptor.
Tripdiolide is an anti-inflammatory isolate of Tripterygium wilfordii.
Triptolidenol is a bioactive diterpene created by Tripterygium wilfordii.
Hypoglaunines are chemical compounds isolated from the bark of Tripterygium hypoglaucum.
Dennstaedtia wilfordii is a species of fern in the family Dennstaedtiaceae. It was formerly placed in the monotypic genus Coptodipteris as Coptidipteris wilfordii. It is native from Pakistan through China to Korea and Japan.
Pseudonocardia rhizophila is a bacterium from the genus of Pseudonocardia which has been isolated from rhizosphere soil from the plant Tripterygium wilfordii in Yunnan in China.
Yang Dan is a Hong Kong-Chinese chemist and chemical biologist. She is the chair professor in both School of Life Sciences and School of Science in the Westlake University. She was awarded the TWAS Prize for Chemistry in 2010 and the Young Woman Scientist Prize of China in 2011.
Stackebrandtia endophytica is an endophytic bacterium from the genus of Stackebrandtia which has been isolated from the stem of the plant Tripterygium wilfordii from Yunnan in China.
A transformer is a deep learning architecture developed by Google and based on the multi-head attention mechanism, proposed in a 2017 paper "Attention Is All You Need". It has no recurrent units, and thus requires less training time than previous recurrent neural architectures, such as long short-term memory (LSTM), and its later variation has been prevalently adopted for training large language models (LLM) on large (language) datasets, such as the Wikipedia corpus and Common Crawl. Text is converted to numerical representations called tokens, and each token is converted into a vector via looking up from a word embedding table. At each layer, each token is then contextualized within the scope of the context window with other (unmasked) tokens via a parallel multi-head attention mechanism allowing the signal for key tokens to be amplified and less important tokens to be diminished. The transformer paper, published in 2017, is based on the softmax-based attention mechanism proposed by Bahdanau et. al. in 2014 for machine translation, and the Fast Weight Controller, similar to a transformer, proposed in 1992.
Triptonide is a chemical compound found in Tripterygium wilfordii, a plant used in traditional Chinese medicine. A 2021 trial in mice and monkeys suggested that triptonide may offer a reversible male contraceptive.
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