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Nial J. Wheate | |
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Born | 1976 Werribee, Victoria, Australia |
Nationality | Australian |
Alma mater | University of New South Wales |
Scientific career | |
Fields | Chemistry |
Institutions | University of Sydney University of Strathclyde University of Western Sydney |
Doctoral advisor | J. Grant Collins |
Nial J. Wheate (born 1976) is an Australian pharmaceutical chemist and author at the University of Sydney.
After completing high school at Copland College in Canberra, Australia, Wheate was appointed an officer in the Royal Australian Navy. He attended the Australian Defence Force Academy, [1] where he studied for a Bachelor of Science degree double majoring in chemistry, graduating in 1997 with Honours Class I for his degree. After a short appointment as a Visiting Military Scholar, Wheate undertook a PhD under the supervision of Associate Professor J. Grant Collins within the School of Physical, Environmental and Mathematical Sciences, at University College, University of New South Wales, with a thesis "Platinum Anticancer Drugs" in 2001. [2]
Over the next three years Wheate was posted to the School of Air Navigation (now the School of Air Combat), RAAF Base East Sale, the Air Coordination and Policy Agency, the Joint Health Support Agency, and the Sea Power Centre – Australia. [3] He left the navy in 2005. He was then appointed a Senior Fellow in the School of Biomedical and Health Sciences at the University of Western Sydney before his appointment as a lecturer in medicinal chemistry at the Strathclyde Institute of Pharmacy and Biomedical Sciences at the University of Strathclyde in Glasgow, Scotland. He is an Associate Professor in the Faculty of Medicine and Health University of Sydney. In 2013 he was appointed the Head of Cancer Research within the Faculty of Pharmacy. [4] In March 2019, Wheate was appointed to the board of Canngea Pty Ltd, an Australian medicinal cannabis manufacturer, as Science Director.
Wheate's research interests are in the field of metal-based drugs. His research group's work includes drug design and synthesis, encapsulation of drugs in macrocycles, attachment of drugs to nanoparticles, drug solid-state stability and polymorphism (materials science), drug mechanisms of action, improving drug solubility through the formation of cocrystals, drug metabolism, drug pre-formulation and formulation, and drug-excipient interactions in various dosage forms. Recent highlighted work has included the development of magnetically directed drug delivery for platinum drugs. [5]
Wheate's work has focused on multinuclear platinum-based drugs [6] and the potential applications of cucurbiturils for drug delivery. [7]
In 2013 Wheate was elected Fellow of the Royal Australian Chemical Institute in recognition of his achievements in cancer research [8] and is also a Fellow of the Higher Education Academy.
Wheate was previously an associate editor of the Australian Journal of Chemistry and is a current editor of the Source Journal of Pharmaceutical Science.
Wheate has also published in a variety of other areas including military justice, [9] naval history, [10] [11] weapons of mass destruction [12] and he has written a novel titled Whikatak Island. [13]
The Royal Australian Navy (RAN) is the naval force of the Australian Defence Force (ADF). The professional head of the RAN is Chief of Navy (CN) Vice Admiral Mark Hammond AM, RAN. CN is also jointly responsible to the Minister of Defence (MINDEF) and the Chief of Defence Force (CDF). The Department of Defence as part of the Australian Public Service administers the ADF.
Pharmacy is the science and practice of discovering, producing, preparing, dispensing, reviewing and monitoring medications, aiming to ensure the safe, effective, and affordable use of medicines. It is a miscellaneous science as it links health sciences with pharmaceutical sciences and natural sciences. The professional practice is becoming more clinically oriented as most of the drugs are now manufactured by pharmaceutical industries. Based on the setting, pharmacy practice is either classified as community or institutional pharmacy. Providing direct patient care in the community of institutional pharmacies is considered clinical pharmacy.
The UCL School of Pharmacy is the pharmacy school of University College London (UCL). The School forms part of UCL's Faculty of Life Sciences and is located in London, United Kingdom.
Cisplatin is a chemical compound with formula cis-[Pt(NH3)2Cl2]. It is a coordination complex of platinum that is used as a chemotherapy medication used to treat a number of cancers. These include testicular cancer, ovarian cancer, cervical cancer, bladder cancer, head and neck cancer, esophageal cancer, lung cancer, mesothelioma, brain tumors and neuroblastoma. It is given by injection into a vein.
The Royal Australian Chemical Institute (RACI) is both the qualifying body in Australia for professional chemists and a learned society promoting the science and practice of chemistry in all its branches. The RACI hosts conferences, seminars and workshops. It is the professional body for chemistry in Australia, with the ability to award the status of Chartered Chemist (CChem) to suitably qualified candidates.
Monash University, Parkville campus is a campus of Monash University, located in Parkville, Victoria, Australia. It is home to the Faculty of Pharmacy and Pharmaceutical Sciences. Founded in 1881 and previously known as the Victorian College of Pharmacy, the faculty is the oldest school of pharmacy in Australia. A major centre of research and teaching, it is internationally regarded for its research in drug target biology and discovery, medicinal chemistry, drug development, formulation science, and medicine use and safety, including the discovery and development of the world's first successful anti-influenza drug, Relenza. In international rankings, it is ranked as the number one school of pharmacy and pharmacology in Australia and number two worldwide.
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Australia was a member of the international coalition which contributed military forces to the 1991 Gulf War, also known as Operation Desert Storm. More than 1,800 Australian Defence Force (ADF) personnel were deployed to the Persian Gulf from August 1990 to September 1991, while contingents from the Royal Australian Navy circulated through the region in support of the sanctions against Iraq until November 2001. In August 1990, two frigates HMAS Adelaide and HMAS Darwin and the replenishment ship HMAS Success left for the Persian Gulf. HMAS Success had no air defences, so the Army 16th Air Defence Regiment was embarked. On 3 December 1990, HMAS Brisbane and HMAS Sydney (IV) relieved HMAS Adelaide and HMAS Darwin. On 26 January 1991, HMAS Westralia replaced HMAS Success. A Navy clearance diving team was also deployed for explosive ordnance disposal and demolition tasks. Australian ships were in danger of sea mines and possible air attacks. In a number of recorded incidents, HMAS Brisbane encountered free floating mines, on one occasion narrowly avoiding a collision. Both HMA Ships Brisbane and Sydney encountered significant air threat warnings from Iran and Iraq throughout the initial period of the commencement of the Desert Storm Campaign. The detection of land based Silkworm anti-ship missiles from Iran throughout the campaign also added to the challenges for both crews as well as the multi-national Naval Forces.
The Australian Defence Organisation (ADO), also known as simply Defence, is an Australian Government organisation that consists of both the Australian Defence Force (ADF) and the Department of Defence (DoD). The ADO's collective aims are to "defend Australia and its national interests" and "protect and advance Australia's strategic interests".
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Rosetta Martiniello-Wilks is an Australian cancer researcher. She is a former senior lecturer at the University of Technology Sydney (UTS) in Ultimo, Sydney, Australia. Martiniello-Wilks was a core member of the Centre for Health Technologies at UTS and head of the Translational Cancer Research Group in the School of Medical and Molecular Biosciences, Faculty of Science, UTS.
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Anthony Steven Weiss AM PhD FRSC FTSE FRSN FRACI, FTERM, FBSE is a university researcher, company founder and entrepreneur. He is the leading scientist in human tropoelastin research and synthetic human elastin. He holds the McCaughey Chair in Biochemistry, heads the Charles Perkins Centre Node in Tissue Engineering and Regenerative Medicine, and is Professor of Biochemistry and Molecular Biotechnology at the University of Sydney. His discoveries are on human elastic materials that accelerate the healing and repair of arteries, skin and 3D human tissue components. He is a Fellow of the Royal Society of Chemistry. Weiss is on the editorial boards of the American Chemical Society Biomaterials Science and Engineering, Applied Materials Today (Elsevier), Biomaterials, Biomedical Materials, BioNanoScience (Springer) and Tissue Engineering. He is a biotechnology company founder, promoter of national and international technology development, and has received national and international awards, including the Order of Australia.
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: CS1 maint: archived copy as title (link) The chemical, biological, radiological and nuclear threat, Papers in Australian Maritime Affairs, 2006, 19, 71-76.