Nicholas Harberd

Last updated

Nicholas Harberd
FRS
Born
Nicholas Paul Harberd

(1956-07-15) 15 July 1956 (age 67)
Alma mater University of Cambridge (MA, PhD)
Known forSeed to Seed: The Secret Life of Plants [1]
Scientific career
Fields Plant biology [2]
Institutions
Thesis A genetical investigation of the alcohol dehydrogenase in barley  (1981)
Website www.biology.ox.ac.uk/people/professor-nicholas-harberd-frs OOjs UI icon edit-ltr-progressive.svg

Nicholas Paul Harberd FRS (born 15 July 1956) [3] is Sibthorpian Professor of Plant Science and former head of the Department of Plant Sciences (since 2022 part of the Department of Biology) at the University of Oxford, and Fellow of St John's College, Oxford. [4] [5] [2] [6]

Contents

Education

Harberd earned a Bachelor of Arts degree with Honours, a Master of Arts, and PhD in 1981, from the University of Cambridge where he was a student of Christ's College, Cambridge.

Career and research

He was a scientist at the Plant Breeding Institute, Trumpington, Cambridge from 1982 to 1986, and the University of California, Berkeley, from 1986 to 1988.

He is head of the Harberd group, which was located at John Innes Centre, and has been at the University of Oxford [7] since his appointment as Sibthorpian Professor of Plant Sciences in 2007. [1] [8] [9] [10] [11] [12] [13] [14] [15]

With George Coupland, Liam Dolan, Alison Smith, Jonathan Jones, Cathie Martin, Robert Sablowski and Abigail Amey he is a co-author of the textbook Plant Biology. [16]

Awards and honours

Harberd was elected a Fellow of the Royal Society (FRS) in 2009. [8] His nomination reads:

Nick Harberd has made pioneering contributions to the solution of a fundamental problem in biology – the molecular mechanisms via which plant hormones control growth. He showed that the hormone gibberellin promotes growth by counteracting a family of nuclear growth-repressing proteins, and that this provides a key mechanism for adaptive regulation of growth in response to environmental change. He also showed how this mechanism underlies the action of genes responsible for the increase in yield of wheat varieties during the 'green revolution'. His discoveries have thus provided many important and original contributions to developmental, evolutionary and agricultural science. [17]

Related Research Articles

<i>Arabidopsis thaliana</i> Model plant species in the family Brassicaceae

Arabidopsis thaliana, the thale cress, mouse-ear cress or arabidopsis, is a small plant from the mustard family (Brassicaceae), native to Eurasia and Africa. Commonly found along the shoulders of roads and in disturbed land, it is generally considered a weed.

Gibberellins (GAs) are plant hormones that regulate various developmental processes, including stem elongation, germination, dormancy, flowering, flower development, and leaf and fruit senescence. GAs are one of the longest-known classes of plant hormone. It is thought that the selective breeding of crop strains that were deficient in GA synthesis was one of the key drivers of the "green revolution" in the 1960s, a revolution that is credited to have saved over a billion lives worldwide.

<span class="mw-page-title-main">Abscisic acid</span> Plant hormone

Abscisic acid is a plant hormone. ABA functions in many plant developmental processes, including seed and bud dormancy, the control of organ size and stomatal closure. It is especially important for plants in the response to environmental stresses, including drought, soil salinity, cold tolerance, freezing tolerance, heat stress and heavy metal ion tolerance.

Jonathan Dallas George Jones is a senior scientist at the Sainsbury Laboratory and a professor at the University of East Anglia using molecular and genetic approaches to study disease resistance in plants.

Florigens are proteins capable of inducing flowering time in angiosperms. The prototypical florigen is encoded by the FT gene and its orthologs in Arabidopsis and other plants. Florigens are produced in the leaves, and act in the shoot apical meristem of buds and growing tips.

<span class="mw-page-title-main">ABC model of flower development</span> Model for genetics of flower development

The ABC model of flower development is a scientific model of the process by which flowering plants produce a pattern of gene expression in meristems that leads to the appearance of an organ oriented towards sexual reproduction, a flower. There are three physiological developments that must occur in order for this to take place: firstly, the plant must pass from sexual immaturity into a sexually mature state ; secondly, the transformation of the apical meristem's function from a vegetative meristem into a floral meristem or inflorescence; and finally the growth of the flower's individual organs. The latter phase has been modelled using the ABC model, which aims to describe the biological basis of the process from the perspective of molecular and developmental genetics.

<span class="mw-page-title-main">Brassinolide</span> Chemical compound

Brassinolide is a plant hormone. The first isolated brassinosteroid, it was discovered when it was shown that pollen from rapeseed could promote stem elongation and cell division. The biologically active component was isolated and named brassinolide.

<span class="mw-page-title-main">David Baulcombe</span> British plant scientist and geneticist

Sir David Charles Baulcombe is a British plant scientist and geneticist. As of 2017 he is a Royal Society Research Professor. From 2007 to 2020 he was Regius Professor of Botany in the Department of Plant Sciences at the University of Cambridge.

<span class="mw-page-title-main">Paclobutrazol</span> Chemical compound

Paclobutrazol (PBZ) is the ISO common name for an organic compound that is used as a plant growth retardant and triazole fungicide. It is a known antagonist of the plant hormone gibberellin, acting by inhibiting gibberellin biosynthesis, reducing internodal growth to give stouter stems, increasing root growth, causing early fruitset and increasing seedset in plants such as tomato and pepper. PBZ has also been shown to reduce frost sensitivity in plants. Moreover, paclobutrazol can be used as a chemical approach for reducing the risk of lodging in cereal crops. PBZ has been used by arborists to reduce shoot growth and shown to have additional positive effects on trees and shrubs. Among those are improved resistance to drought stress, darker green leaves, higher resistance against fungi and bacteria, and enhanced development of roots. Cambial growth, as well as shoot growth, has been shown to be reduced in some tree species.

GAI or Gibberellic-Acid Insensitive is a gene in Arabidopsis thaliana which is involved in regulation of plant growth. GAI represses the pathway of gibberellin-sensitive plant growth. It does this by way of its conserved DELLA motif.

George Michael Coupland FRS is a Scottish plant scientist, and Research Scientist and Director of the Max Planck Institute for Plant Breeding Research.

<span class="mw-page-title-main">Cathie Martin</span> British botanist

Catherine Rosemary Martin is a Professor of Plant Sciences at the University of East Anglia (UEA) and project leader at the John Innes Centre, Norwich, co-ordinating research into the relationship between diet and health and how crops can be fortified to improve diets and address escalating chronic disease globally.

<span class="mw-page-title-main">Liam Dolan</span>

Liam Dolan is a Senior Group Leader at the Gregor Mendel Institute of Molecular Plant Biology (GMI) of the Austrian Academy of Sciences, the Sherardian Professor of Botany in the Department of Biology at the University of Oxford and a Fellow of Magdalen College, Oxford.

Jane Elizabeth Parker is a British scientist who researches the immune responses of plants at the Max Planck Institute for Plant Breeding Research.

<span class="mw-page-title-main">Alison Mary Smith</span> British biologist (born 1954)

Alison Mary Smith is a British biologist. She is Strategic Programme Leader at the John Innes Centre in Norwich and an Honorary Professor at the University of East Anglia (UEA) in the UK.

<span class="mw-page-title-main">Ian A. Graham</span> British biologist (born 1963)

Ian Alexander Graham is a professor of Biochemical Genetics in the Centre for Novel Agricultural Products (CNAP) at the University of York.

<span class="mw-page-title-main">Peter J. Davies</span>

Peter John Davies is a professor emeritus of Plant Physiology in the Departments of Plant Biology and Horticulture at Cornell University who is notable for his work on plant development, plant hormones, and in educating the public on agricultural technology and genetically modified organisms (GMOs) as a Jefferson Science Fellow from 2011 to 2014. As a Jefferson Science Fellow Davies monitored developments in agriculture and food security, monitored the status of biotech crops in Europe, and provided input to promote the acceptance of these crops on a scientific basis.

<span class="mw-page-title-main">Sarah Wyatt</span> American molecular biologist

Sarah Wyatt is an American, plant molecular biologist. She is a Professor in the Department of Environmental and Plant Biology at Ohio University, as well as director of the Ohio University Interdisciplinary Graduate Program in Molecular and Cellular Biology. Wyatt's research interests include molecular biology, genomics, and signaling events. She is considered one of the world's experts on gravitational signaling in plants, and some of her recent research includes an experiment on board the International Space Station (ISS).

Jian-Kang Zhu is a plant scientist, researcher and academic. He is a Senior Principal Investigator in the Shanghai Center for Plant Stress Biology, Chinese Academy of Sciences (CAS). He is also the Academic Director of CAS Center of Excellence in Plant Sciences.

Christoph Benning is a German–American plant biologist. He is an MSU Foundation Professor and University Distinguished Professor at Michigan State University. Benning's research into lipid metabolism in plants, algae and photosynthetic bacteria, led him to be named Editor-in-Chief of The Plant Journal in October 2008.

References

  1. 1 2 Harberd, Nicholas (2006). Seed to Seed: The Secret Life of Plants . Bloomsbury Publishing. ISBN   978-0-7475-7039-4.
  2. 1 2 Nicholas Harberd publications indexed by Google Scholar OOjs UI icon edit-ltr-progressive.svg
  3. Anon (2017). "Harberd, Prof. Nicholas Paul" . Who's Who (online Oxford University Press  ed.). Oxford: A & C Black. doi:10.1093/ww/9780199540884.013.U245781.(Subscription or UK public library membership required.)
  4. "Prof Nicholas Harberd, Sibthorpian Professor of Plant Science and Fellow of St. John's College". University of Oxford. 24 September 2009. Archived from the original on 29 August 2010. Retrieved 27 February 2012.
  5. Nicholas Harberd publications indexed by the Scopus bibliographic database. (subscription required)
  6. Nicholas Harberd publications from Europe PubMed Central
  7. "Plant Sciences Staff: Prof. NP Harberd". University of Oxford. December 2011. Retrieved 27 February 2012.
  8. 1 2 "New Royal Society Fellows". University of Oxford. Archived from the original on 2 December 2012. Retrieved 9 March 2012.
  9. Colin Tudge (24 March 2006). "Genes by the wayside". The Guardian .
  10. Harberd, N. P.; Peng, J.; Richards, D. E.; Hartley, N. M.; Murphy, G. P.; Devos, K. M.; Flintham, J. E.; Beales, J.; Fish, L. J.; Worland, A. J.; Pelica, F.; Sudhakar, D.; Christou, P.; Snape, J. W.; Gale, M. D. (1999). "'Green revolution' genes encode mutant gibberellin response modulators". Nature. 400 (6741): 256–61. Bibcode:1999Natur.400..256P. doi:10.1038/22307. PMID   10421366. S2CID   4363793.
  11. Fu, X.; Harberd, N. P. (2003). "Auxin promotes Arabidopsis root growth by modulating gibberellin response". Nature. 421 (6924): 740–3. Bibcode:2003Natur.421..740F. doi:10.1038/nature01387. PMID   12610625. S2CID   2719281.
  12. Peng, J.; Carol, P.; Richards, D. E.; King, K. E.; Cowling, R. J.; Murphy, G. P.; Harberd, N. P. (1997). "The Arabidopsis GAI gene defines a signaling pathway that negatively regulates gibberellin responses". Genes & Development. 11 (23): 3194–205. doi:10.1101/gad.11.23.3194. PMC   316750 . PMID   9389651.
  13. Achard, P.; Cheng, H; De Grauwe, L; Decat, J; Schoutteten, H; Moritz, T; Van Der Straeten, D; Peng, J; Harberd, N. P. (2006). "Integration of Plant Responses to Environmentally Activated Phytohormonal Signals". Science. 311 (5757): 91–4. Bibcode:2006Sci...311...91A. doi:10.1126/science.1118642. PMID   16400150. S2CID   32781916.
  14. Achard, P.; Herr, A; Baulcombe, D. C.; Harberd, N. P. (2004). "Modulation of floral development by a gibberellin-regulated microRNA". Development. 131 (14): 3357–65. doi:10.1242/dev.01206. PMID   15226253.
  15. "Professor Nick Harberd elected Fellow of the Royal Society". jic.ac.uk. Retrieved 26 September 2018.
  16. Smith, Alison Mary; Coupand, George; Dolan, Liam; Harberd, Nicholas; Jones, Jonathan; Martin, Cathie; Sablowski, Robert; Amey, Abigail (2009). Plant Biology . Garland Science. ISBN   978-0815340256.
  17. "EC/2009/16: Harberd, Nicholas Paul". London: The Royal Society. Archived from the original on 20 June 2014.