OR4F5

OR4F5
Identifiers
Aliases	OR4F5 , olfactory receptor family 4 subfamily F member 5
External IDs	HomoloGene: 128250 GeneCards: OR4F5
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1p36.33 Start 65,419 bp [1] End 71,585 bp [1]
RNA expression pattern Bgee Top expressed in ovary muscle of leg esophagus gastrocnemius muscle stomach body of stomach colon More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity transmembrane signaling receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell detection of chemical stimulus involved in sensory perception signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	79501	n/a
Ensembl	ENSG00000186092	n/a
UniProt	Q8NH21	n/a
RefSeq (mRNA)	NM_001005484	n/a
RefSeq (protein)	NP_001005484	n/a
Location (UCSC)	Chr 1: 0.07 – 0.07 Mb	n/a
PubMed search	[2]	n/a
Wikidata
View/Edit Human

Olfactory receptor family 4 subfamily F member 5 is a protein that in humans is encoded by the OR4F5 gene. ^[3]

Function

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

Trivia

OR4F5 is the first protein coding gene on human chromosome 1.

References

1. GRCh38: Ensembl release 89: ENSG00000186092 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Entrez Gene: Olfactory receptor family 4 subfamily F member 5".

This article incorporates text from the United States National Library of Medicine, which is in the public domain.