X-ray crystallography is the experimental science of determining the atomic and molecular structure of a crystal, in which the crystalline structure causes a beam of incident X-rays to diffract in specific directions. By measuring the angles and intensities of the X-ray diffraction, a crystallographer can produce a three-dimensional picture of the density of electrons within the crystal and the positions of the atoms, as well as their chemical bonds, crystallographic disorder, and other information.
Biophysics is an interdisciplinary science that applies approaches and methods traditionally used in physics to study biological phenomena. Biophysics covers all scales of biological organization, from molecular to organismic and populations. Biophysical research shares significant overlap with biochemistry, molecular biology, physical chemistry, physiology, nanotechnology, bioengineering, computational biology, biomechanics, developmental biology and systems biology.
John Kuriyan is the dean of basic sciences and a professor of biochemistry at Vanderbilt University School of Medicine. He was formerly the Chancellor's Professor at the University of California, Berkeley in the departments of molecular and cell biology (MCB) and chemistry, a faculty scientist in Berkeley Lab's physical biosciences division, and a Howard Hughes Medical Institute investigator. He is a member of the National Academy of Sciences and he has also been on the Life Sciences jury for the Infosys Prize in 2009, 2019 and 2020.
Dame Janet Maureen Thornton, is a senior scientist and director emeritus at the European Bioinformatics Institute (EBI), part of the European Molecular Biology Laboratory (EMBL). She is one of the world's leading researchers in structural bioinformatics, using computational methods to understand protein structure and function. She served as director of the EBI from October 2001 to June 2015, and played a key role in ELIXIR.
Acta Crystallographica is a series of peer-reviewed scientific journals, with articles centred on crystallography, published by the International Union of Crystallography (IUCr). Originally established in 1948 as a single journal called Acta Crystallographica, there are now six independent Acta Crystallographica titles:
Helen Miriam Berman is a Board of Governors Professor of Chemistry and Chemical Biology at Rutgers University and a former director of the RCSB Protein Data Bank. A structural biologist, her work includes structural analysis of protein-nucleic acid complexes, and the role of water in molecular interactions. She is also the founder and director of the Nucleic Acid Database, and led the Protein Structure Initiative Structural Genomics Knowledgebase.
Peter Jay Hotez is an American scientist, pediatrician, and advocate in the fields of global health, vaccinology, and neglected tropical disease control. He serves as founding dean of the National School of Tropical Medicine, Professor of Pediatrics and Molecular Virology & Microbiology at Baylor College of Medicine, where he is also Director of the Texas Children's Hospital Center for Vaccine Development and Endowed Chair in Tropical Pediatrics, and University Professor of Biology at Baylor College of Medicine.
Ruth Nussinov is an Israeli-American biologist born in Rehovot who works as a Professor in the Department of Human Genetics, School of Medicine at Tel Aviv University and is the Senior Principal Scientist and Principal Investigator at the National Cancer Institute, National Institutes of Health. Nussinov is also the Editor in Chief of the Current Opinion in Structural Biology and formerly of the journal PLOS Computational Biology.
Ada E. Yonath is an Israeli crystallographer and Nobel laureate in Chemistry, best known for her pioneering work on the structure of ribosomes. She is the current director of the Helen and Milton A. Kimmelman Center for Biomolecular Structure and Assembly of the Weizmann Institute of Science.
James Henderson Naismith is Professor of Structural Biology at the University of Oxford, former Director of the Research Complex at Harwell and Director of the Rosalind Franklin Institute. He previously served as Bishop Wardlaw Professor of Chemical Biology at the University of St Andrews. He was a member of Council of the Royal Society (2021-2022). He is currently the Vice-Chair of Council of the European X-ray Free Electron Laser and Vice-President (non-clinical) of The Academy of Medical Sciences. It has been announced that he will be the Head of the MPLS division at Oxford in the autumn of 2023.
Maria Elena Bottazzi is an American microbiologist. As of 2024 she is associate dean of the National School of Tropical Medicine at Baylor College of Medicine, as well as Distinguished Professor of Biology at Baylor University, Waco, Texas. She is editor-in-chief of Springer's Current Tropical Medicine Reports. She and Peter Hotez led the team that designed COVID-19 vaccine Corbevax.
Sabin Vaccine Institute, located in Washington, D.C., is a nonprofit organization promoting global vaccine development, availability, and use. Through its work, Sabin hopes to reduce human suffering by preventing the spread of vaccine-preventable, communicable disease in humans through herd immunity and mitigating the poverty caused by these diseases.
Ponnuraj Karthe is an Indian structural biologist and a professor and the head of the Department of Crystallography and Biophysics of the University of Madras. He is known for his research in the fields of structural biology and drug designing. His studies have been documented by way of a number of articles and Google Scholar, an online repository of scientific articles has listed 46 of them. Besides, he has contributed chapters to books edited by others and has delivered invited speeches at many seminars which include the Workshop on Advances in Computer Aided Drug Design held in August 2010 at the University of Madras. He was a member of the national organizing committee of the Annual Conference of Indian Biophysical Society - Molecular Architecture, Dynamics and Assem, organized by Saha Institute of Nuclear Physics and serves as a member of the national committee of the International Union for Pure and Applied Biophysics (IUPAB) as well as the executive council of the Bioinformatics and Drug Discovery Society (BIDDS), a non governmental organization promoting dissemination of knowledge in the fields of bioinformatics, biological sciences and other life sciences. The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for his contributions to biosciences, in 2010.
Krystle McLaughlin is a Caribbean-American structural biophysicist. She is an assistant professor of chemistry at Vassar College.
Janet Louise Smith is the Margaret J. Hunter Collegiate Professor in the Life Sciences Institute, director of the Center for Structural Biology at the University of Michigan, professor of biological chemistry and biophysics at the University of Michigan, and research professor in the Life Sciences Institute. Additionally, she is the scientific director of The General Medical Sciences and Cancer Institutes’ structural biology facility at the Advanced Photon Source.
Jue Chen is a Chinese-born American structural biologist and biochemist. She is the William E. Ford professor of biochemistry and head of the Laboratory of Membrane Biology and Biophysics at the Rockefeller University and a Howard Hughes Medical Institute investigator. Her research focuses on elucidating the structure and function of ATP-binding cassette (ABC) transporters.
Elizabeth Dickinson Getzoff is an American biochemist. She holds a joint appointment at Scripps Research Institute in California, as professor emeritus in immunology and Microbiology, as well as integrative structural and computational biology (ISCB)
Tracey Maureen Gloster is a chemist at the University of St Andrews UK. Her research interests are in structural biology, chemical biology, glycobiology and carbohydrate processing enzymes.
Gaetano T. Montelione is an American biophysical chemist, Professor of Chemistry and Chemical Biology, and Constellation Endowed Chair in Structural Bioinformatics at Rensselaer Polytechnic Institute in Troy, NY.
Bonnie Ann Wallace, FRSC is a British and American biophysicist and biochemist. She is a professor of molecular biophysics in the department of biological sciences, formerly the department of crystallography, at Birkbeck College, University of London, U.K.
