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In molecular biology, MvirDB is a publicly available database that stores information on toxins, virulence factors and antibiotic resistance genes. Sources that this database uses for DNA and protein information include: Tox-Prot, SCORPION, the PRINTS Virulence Factors, VFDB, TVFac, Islander, ARGO and VIDA. The database provides a BLAST tool that allows the user to query their sequence against all DNA and protein sequences in MvirDB. Information on virulence factors can be obtained from the usage of the provided browser tool. Once the browser tool is used, the results are returned as a readable table that is organized by ascending E-Values, each of which are hyperlinked to their related page. MvirDB is implemented in an Oracle 10g relational database.
Jessica Kissinger is a Distinguished Research Professor at the Franklin College of Arts and Sciences, University of Georgia and director of the Institute of Bioinformatics. Her research focus is on the evolution, assembly and data curation of protozoan parasite genomes, particularly Cryptosporidium, Toxoplasma gondii and Plasmodium.
Judith Anne Blake is a computational biologist at the Jackson Laboratory and Professor of Mammalian Genetics.
References
- ↑ Kafkas, Şenay; Abdelhakim, Marwa; Hashish, Yasmeen; Kulmanov, Maxat; Abdellatif, Marwa; Schofield, Paul N.; Hoehndorf, Robert (2019-06-03). "PathoPhenoDB, linking human pathogens to their phenotypes in support of infectious disease research". Scientific Data. 6 (1): 79. Bibcode:2019NatSD...6...79K. doi:10.1038/s41597-019-0090-x. ISSN 2052-4463. PMC 6546783 . PMID 31160594.
- ↑ Schriml, Lynn M.; Parkinson, Helen; Vasant, Drashtti; Malone, James; Binder, Janos X.; Mungall, Christopher J.; Fu, Gang; Bolton, Evan; Mitraka, Elvira (2015-01-28). "Disease Ontology 2015 update: an expanded and updated database of human diseases for linking biomedical knowledge through disease data". Nucleic Acids Research. 43 (D1): D1071–D1078. doi:10.1093/nar/gku1011. ISSN 0305-1048. PMC 4383880 . PMID 25348409.
- ↑ Robinson, Peter N.; Köhler, Sebastian; Bauer, Sebastian; Seelow, Dominik; Horn, Denise; Mundlos, Stefan (2008-11-17). "The Human Phenotype Ontology: A Tool for Annotating and Analyzing Human Hereditary Disease". The American Journal of Human Genetics. 83 (5): 610–615. doi:10.1016/j.ajhg.2008.09.017. ISSN 0002-9297. PMC 2668030 . PMID 18950739.
- ↑ Richardson, Joel E.; Kadin, James A.; Bult, Carol J.; Blake, Judith A.; Eppig, Janan T. (2015-01-28). "The Mouse Genome Database (MGD): facilitating mouse as a model for human biology and disease". Nucleic Acids Research. 43 (D1): D726–D736. doi:10.1093/nar/gku967. ISSN 0305-1048. PMC 4384027 . PMID 25348401.
- ↑ Bork, Peer; Jensen, Lars Juhl; Letunic, Ivica; Kuhn, Michael (2016-01-04). "The SIDER database of drugs and side effects". Nucleic Acids Research. 44 (D1): D1075–D1079. doi: 10.1093/nar/gkv1075 . ISSN 0305-1048. PMC 4702794 . PMID 26481350.
- ↑ McArthur, Andrew G.; Wright, Gerard D.; Brinkman, Fiona S. L.; Johnson, Timothy A.; Pawlowski, Andrew C.; Westman, Erin L.; Sardar, Daim; Elsayegh, Tariq; Frye, Jonathan G. (2017-01-04). "CARD 2017: expansion and model-centric curation of the comprehensive antibiotic resistance database". Nucleic Acids Research. 45 (D1): D566–D573. doi: 10.1093/nar/gkw1004 . ISSN 0305-1048. PMC 5210516 . PMID 27789705.
- ↑ Church, Kenneth Ward; Hanks, Patrick (March 1990). "Word Association Norms, Mutual Information, and Lexicography". Comput. Linguist. 16 (1): 22–29. ISSN 0891-2017.
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