Pearl gene

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Pseudo-double dilute from action of pearl gene The Andalusian X Lusitano cross is known on the Iberian Peninsula as the "Golden Cross" . . ..JPG
Pseudo-double dilute from action of pearl gene

The Pearl gene, also known as the "Barlink factor", is a dilution gene at the same locus as the cream gene, which somewhat resembles the cream gene and the champagne gene but is unrelated to champagne. It is a somewhat rare dilution gene found in the American Quarter Horse, American Paint Horse, and Peruvian Paso. [2] [3] The same mutation appears in Iberian horse breeds such as the Lusitano and Andalusian. The existence of the pearl gene in Quarter Horses and Paints is probably because these breeds have some Iberian ancestors. [2]

It is a recessive gene. If there is only one copy of the gene, it has no effect on black, bay or chestnut horses. If there are two copies, it lightens red coats to a pale, uniform apricot color that includes body, mane and tail and creates pale skin. [2] Because of this effect, when research was underway to locate the specific gene involved, it was at one time referred to as the "apricot" gene. [4]

The Pearl gene is also known to interact with the cream gene to enhance its effects and, in horses with only one copy of the cream allele, to create "pseudo-double dilutes" sometimes called pseudo-cremellos or pseudo-smoky cream. A pseudo-double dilute will often have pale skin and blue or green eyes. [2] Unlike the double cream dilute and the Pearl-cream pseudo dilute the double Pearl dilute typically has dark tan eyes. It is difficult if not impossible to tell a double cream dilute from a Pearl-cream pseudo dilute without genetic testing. Pearl is found at SLC45A2 (also called MATP), the same locus as cream, sunshine, and snowdrop. [5] [6] [7]

In the American Paint Horse breed, the dilution was called the "Barlink factor" because it was linked to a mare named My Tontime, [8] and her grandson, the stallion Barlink Macho Man, a chestnut splashed white. [9] Initially, the gene in Paints and Quarter Horses was thought to be a different allele than that in the Iberian breeds, but research demonstrated that it was the same gene. [2]

Related Research Articles

<span class="mw-page-title-main">Palomino</span> Genetic color in horses

Palomino is a genetic color in horses, consisting of a gold coat and white mane and tail; the degree of whiteness can vary from bright white to yellow. The palomino color derived from the inter-breeding of Spanish horses with those from the United States. Genetically, the palomino color is created by a single allele of a dilution gene called the cream gene working on a "red" (chestnut) base coat. Palomino is created by a genetic mechanism of incomplete dominance, hence it is not considered true-breeding. However, most color breed registries that record palomino horses were founded before equine coat color genetics were understood as well as they are today, therefore the standard definition of a palomino is based on the visible coat color, not heritability nor the underlying presence of the dilution gene.

<span class="mw-page-title-main">Dilution gene</span> Gene that lightens the coat colour of certain animals

A dilution gene is any one of a number of genes that act to create a lighter coat color in living creatures. There are many examples of such genes:

<span class="mw-page-title-main">Cat coat genetics</span> Genetics responsible for the appearance of a cats fur

Cat coat genetics determine the coloration, pattern, length, and texture of feline fur. The variations among cat coats are physical properties and should not be confused with cat breeds. A cat may display the coat of a certain breed without actually being that breed. For example, a Neva Masquerade could wear point coloration, the stereotypical coat of a Siamese.

<span class="mw-page-title-main">Lethal white syndrome</span> Genetic disorder in horses

Lethal white syndrome (LWS), also called overo lethal white syndrome (OLWS), lethal white overo (LWO), and overo lethal white foal syndrome (OLWFS), is an autosomal genetic disorder most prevalent in the American Paint Horse. Affected foals are born after the full 11-month gestation and externally appear normal, though they have all-white or nearly all-white coats and blue eyes. However, internally, these foals have a nonfunctioning colon. Within a few hours, signs of colic appear; affected foals die within a few days. Because the death is often painful, such foals are often humanely euthanized once identified. The disease is particularly devastating because foals are born seemingly healthy after being carried to full term.

<span class="mw-page-title-main">Buckskin (horse)</span> Equine coat color

Buckskin is a colour of horse that is commonly misconceived for being a breed of horse. Buckskins coloring is a hair coat color referring to a color that resembles certain shades of tanned deerskin. Similar colors in some breeds of dogs are also called buckskin. The horse has a tan or gold colored coat with black points. Buckskin occurs as a result of the cream dilution gene acting on a bay horse. Therefore, a buckskin has the Extension, or "black base coat" (E) gene, the agouti gene (A) gene, which restricts the black base coat to the points, and one copy of the cream gene (CCr), which lightens the red/brown color of the bay coat to a tan/gold.

<span class="mw-page-title-main">Gray horse</span> Coat color characterized by progressive depigmentation of the colored hairs of the coat

A gray horse has a coat color characterized by progressive depigmentation of the colored hairs of the coat. Most gray horses have black skin and dark eyes; unlike some equine dilution genes and some other genes that lead to depigmentation, gray does not affect skin or eye color. Gray horses may be born any base color, depending on other color genes present. White hairs begin to appear at or shortly after birth and become progressively more prevalent as the horse ages as white hairs become intermingled with hairs of other colors. Graying can occur at different rates—very quickly on one horse and very slowly on another. As adults, most gray horses eventually become completely white, though some retain intermixed light and dark hairs.

<span class="mw-page-title-main">Cream gene</span> Gene for several horse coat colors

The cream gene is responsible for a number of horse coat colors. Horses that have the cream gene in addition to a base coat color that is chestnut will become palomino if they are heterozygous, having one copy of the cream gene, or cremello, if they are homozygous. Similarly, horses with a bay base coat and the cream gene will be buckskin or perlino. A black base coat with the cream gene becomes the not-always-recognized smoky black or a smoky cream. Cream horses, even those with blue eyes, are not white horses. Dilution coloring is also not related to any of the white spotting patterns.

<span class="mw-page-title-main">Champagne gene</span> Simple dominant allele responsible for a number of rare horse coat colors

The champagne gene is a simple dominant allele responsible for a number of rare horse coat colors. The most distinctive traits of horses with the champagne gene are the hazel eyes and pinkish, freckled skin, which are bright blue and bright pink at birth, respectively. The coat color is also affected: any hairs that would have been red are gold, and any hairs that would have been black are chocolate brown. If a horse inherits the champagne gene from either or both parents, a coat that would otherwise be chestnut is instead gold champagne, with bay corresponding to amber champagne, seal brown to sable champagne, and black to classic champagne. A horse must have at least one champagne parent to inherit the champagne gene, for which there is now a DNA test.

<span class="mw-page-title-main">Silver dapple gene</span>

The silver or silver dapple (Z) gene is a dilution gene that affects the black base coat color and is associated with Multiple Congenital Ocular Abnormalities. It will typically dilute a black mane and tail to a silvery gray or flaxen color, and a black body to a chocolaty brown, sometimes with dapples. It is responsible for a group of coat colors in horses called "silver dapple" in the west, or "taffy" in Australia. The most common colors in this category are black silver and bay silver, referring to the respective underlying coat color.

<span class="mw-page-title-main">Equine coat color genetics</span> Genetics behind the equine coat color

Equine coat color genetics determine a horse's coat color. Many colors are possible, but all variations are produced by changes in only a few genes. Bay is the most common color of horse, followed by black and chestnut. A change at the agouti locus is capable of turning bay to black, while a mutation at the extension locus can turn bay or black to chestnut.

<span class="mw-page-title-main">Dun gene</span> Dilution gene

The dun gene is a dilution gene that affects both red and black pigments in the coat color of a horse. The dun gene lightens most of the body while leaving the mane, tail, legs, and primitive markings the shade of the undiluted base coat color. A dun horse always has a dark dorsal stripe down the middle of its back, usually has a darker face and legs, and may have transverse striping across the shoulders or horizontal striping on the back of the forelegs. Body color depends on the underlying coat color genetics. A classic "bay dun" is a gray-gold or tan, characterized by a body color ranging from sandy yellow to reddish brown. Duns with a chestnut base may appear a light tan shade, and those with black base coloration are a smoky gray. Manes, tails, primitive markings, and other dark areas are usually the shade of the undiluted base coat color. The dun gene may interact with all other coat color alleles.

<span class="mw-page-title-main">Fjord horse</span> Breed of horse

The Fjord or Norwegian Fjord Horse is a relatively small but very strong horse breed from the mountainous regions of western Norway. It is an agile breed of light draught horse build. It is always dun in colour, with five variations in shade recognised in the breed standard. One of the world's oldest breeds, it has been used for hundreds of years as a farm horse in Norway, and in modern times is popular for its generally good temperament. It is used both as a harness horse and under saddle.

<span class="mw-page-title-main">Chestnut (horse color)</span> Horse coat color

Chestnut is a hair coat color of horses consisting of a reddish-to-brown coat with a mane and tail the same or lighter in color than the coat. Chestnut is characterized by the absolute absence of true black hairs. It is one of the most common horse coat colors, seen in almost every breed of horse.

<span class="mw-page-title-main">Equine coat color</span> Horse coat colors and markings

Horses exhibit a diverse array of coat colors and distinctive markings. A specialized vocabulary has evolved to describe them.

<span class="mw-page-title-main">White horse</span> Horse coat color

A white horse is born predominantly white and stays white throughout its life. A white horse has mostly pink skin under its hair coat, and may have brown, blue, or hazel eyes. "True white" horses, especially those that carry one of the dominant white (W) genes, are rare. Most horses that are commonly referred to as "white" are actually "gray" horses whose hair coats are completely white. Gray horses may be born of any color and their hairs gradually turn white as time goes by and take on a white appearance. Nearly all gray horses have dark skin, except under any white markings present at birth. Skin color is the most common method for an observer to distinguish between mature white and gray horses.

<span class="mw-page-title-main">Sabino horse</span> Color pattern in horses

Sabino describes a distinct pattern of white spotting in horses. In general, Sabino patterning is visually recognized by roaning or irregular edges of white markings, belly spots, white extending past the eyes or onto the chin, white above the knees or hocks, and "splash" or "lacy" marks anywhere on the body. Some sabinos have patches of roan patterning on part of the body, especially the barrel and flanks. Some sabinos may have a dark leg or two, but many have four white legs. Sabino patterns may range from slightly bold face or leg white markings—as little as white on the chin or lower lip—to horses that are fully white.

<span class="mw-page-title-main">Smoky black</span>

Smoky black or black carrying cream is a coat color of horses which has the same phenotype as black. Smoky black is produced by the action of a heterozygous cream gene on an underlying black coat color. Therefore, smoky black is a member of the cream family of coat color dilutions, and found in horse populations that have other cream-based colors such as palomino, buckskin, perlino, cremello and smoky cream. All smoky blacks must have at least one parent with the cream gene, and a smoky black can only be verified through DNA testing or parentage. Smoky black has been mistaken for faded black, dark bay or brown, grullo or even liver chestnut.

<span class="mw-page-title-main">Labrador Retriever coat colour genetics</span> Genetics behind Labrador Retriever coat colour

The genetic basis of coat colour in the Labrador Retriever has been found to depend on several distinct genes. The interplay among these genes is used as an example of epistasis.

<span class="mw-page-title-main">Dominant white</span> Horse coat color and its genetics

Dominant white (W) is a group of genetically related coat color alleles on the KIT gene of the horse, best known for producing an all-white coat, but also able to produce various forms of white spotting, as well as bold white markings. Prior to the discovery of the W allelic series, many of these patterns were described by the term sabino, which is still used by some breed registries.

<span class="mw-page-title-main">Dog coat genetics</span> Genetics behind dog coat

Dogs have a wide range of coat colors, patterns, textures and lengths. Dog coat color is governed by how genes are passed from dogs to their puppies and how those genes are expressed in each dog. Dogs have about 19,000 genes in their genome but only a handful affect the physical variations in their coats. Most genes come in pairs, one being from the dog's mother and one being from its father. Genes of interest have more than one expression of an allele. Usually only one, or a small number of alleles exist for each gene. In any one gene locus a dog will either be homozygous where the gene is made of two identical alleles or heterozygous where the gene is made of two different alleles.

References

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  7. Bisbee; Carpenter; Brooks; Lafayette (2020). "Identification of a novel missense variant in SLC45A2 associated with dilute snowdrop phenotype in Gypsy horses". Animal Genetics. 51 (2): 342–343. doi:10.1111/age.12913. PMID   31961951. S2CID   210869996.
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