Personal lubricant

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Various personal lubricants Gleitmittel Personal Lubricants.jpg
Various personal lubricants

Personal lubricants (colloquially termed lube) are specialized lubricants used during sexual acts, such as intercourse and masturbation, to reduce friction to or between the penis and vagina, anus or other body parts or applied to sex toys to reduce friction or to ease penetration. As of 2015, the personal lubricant market was estimated to be worth at least $400 million. [1]

Contents

Surgical or medical lubricants or gels, which are similar to personal lubricants but not usually referred to or labelled as "personal" lubricants, may be used for medical purposes such as speculum insertion or introduction of a catheter. The primary difference between personal and surgical lubricants is that surgical lubricants are thicker, sterile gels, typically containing a bacteriostatic agent. [2]

Types

By composition

Water-based

Water-based personal lubricants are water-soluble and are the most widely used personal lubricants. The earliest water-based lubricants were cellulose ether or glycerin solutions. Products available today may have various agents added for even dispersal, moisture retention, and resistance to contamination. The viscosity of these products can be altered by adjusting their water content and concentration of cellulose or other gel-forming hydrophilic ingredient. Because water-based personal lubricants absorb into the skin and evaporate, most water-based lubricants have a tendency to dry out during use, but reapplication of the lubricant or application of water or saliva is usually sufficient to reactivate them. When the lubricant eventually dries out, it may leave behind a residue derived from the other ingredients in the formulation. This may require reapplication during sex, and/or removal of the residue with water. Scientists are testing whether anti-retroviral lubricants or gels can be applied to aid in the prevention of transmission of HIV. [3]

Typical water-based lubricants may be incompatible with sex acts that occur in water (such as in a bathtub, pool, or hot tub) as they can be dissolved or dispersed in water.

The Population Council, in a 2011 study, tested commercially available water-based sexual lubricants, and found that many damaged human rectal cells and that some of them – those containing polyquaternium-15 – appeared to actively increase HIV replication in cell cultures and therefore could raise one's risk of HIV transmission. Water-based 'lubes' have been recommended for use in safer sex because they do not weaken condoms like oil-based lubricants do. The researchers concluded: "Since it is the condom that is protecting users from HIV rather than the lube, condom users should still be encouraged to use water-based lubes because condoms are also more likely to break, and trauma to the rectal lining occur, with no lube". They also cited silicone-based lubricants as a potential alternative, although they did not test any silicone lubes in their study. [4]

A later study has validated the findings of the Population Council for some water-based products' hyper-osmolality causing some human's cells damage, and better bio-compatibility with low-osmolality water-based products and silicone-based products but failed to corroborate polyquaternium 15 having a role that binds HIV to rectal cells or increase HIV replication. [5]

Oil-based

Oil-based

for example petroleum-based lubricants (such as petroleum jelly), can increase the likelihood of breakage and slipping of latex condoms due to loss of elasticity caused by these lubricants. [6]  Oil-based lubricants may be considered desirable for people who are in relationships not requiring condom use and who wish to avoid certain additives and preservatives often found in other lubricants.

Silicone-based

Silicone-based lubricants do not contain any water. They offer a different feel from water-based personal lubricants. Silicone-based lubricants are not absorbed by skin or mucous membranes and consequently last longer than water-based lubricants. Many different silicone lubricants are commercially available, with varying quality and performance. Not all silicone-based lubricants are certified latex-safe, but silicone-based lubricants have not been shown to increase the risk of HIV transmission during anal intercourse, as some water-based lubes have. [7] [8]

Silicone-based lubricants are not usually recommended for use with sex toys or other products that are made from silicone because the formula may dissolve the surface, making it sticky to the touch, and cause disintegration of the item over time. [8] This damage may create a breeding ground for bacteria. In most cases, a warning is listed on the product label. Silicone-based lubricant is also used in the manufacture of pre-lubricated condoms, due to its long-lasting properties and superior latex compatibility.

By usage

Vaginal lubricants

Vaginal lubricants are used to augment vaginal lubrication and reduce vaginal dryness and pain during intercourse, and by couples trying to conceive. During fertility interventions, the use of a lubricant eases sperm specimen collection by masturbation. Commonly used lubricants include saliva, oil (such as baby oil, olive oil, canola oil, or mineral oil) or commercially available lubricants that are either water-based or hydroxyethylcellulose-based. [9]

Human saliva and olive oil have been found to be detrimental to sperm function. [10] [11] [12] Certain commonly used commercial lubricants, although labeled as non-spermicidal or spermicidal agent-free, have been found to impair sperm function, [11] [13] [14] [15] [16] with several of these lubricants being as toxic to sperm in vitro as contraceptive gels. [17] Sperm motility and viability were found to be disrupted shortly after direct contact between sperm and those lubricants or in saliva. [11] [13] [18] [19] Sperm function could be compromised following lubricant contact, due to the specific ingredients in the lubricant or due to the chemical properties of the lubricant, such as highly raised osmolarity or low pH. [16] [20] Such lubricants are therefore unsafe for use during fertility procedures such as semen collection [11] [13] [14] [17] or by couples trying to conceive by natural or assisted reproduction. [11] [13] [21] [19]

Vaginal lubricants such as mineral oil, canola oil, or hydroxyethylcellulose-based lubricants are recommended for use by couples attempting conception by The Practice Committee of the American Society for Reproductive Medicine. [9] [10] [11] [17] [16] [20] [22] [23] [24]

Anal-specific

Many lubricants are safe for anal sex, but there are products that are specifically marketed or designed to enhance enjoyment of anal sex. Often, this is simply a thicker gel rather than a liquid. This thicker consistency is preferable because it helps the lubricant stay in place. Some anal lubricants contain numbing agents to relieve discomfort during anal sex, although it is generally inadvisable as a lack of sensation makes accidental injury more likely. Additionally, a commonly used numbing agent benzocaine can cause an allergic reaction in those with an allergy to PABA (4-aminobenzoic acid). Some lubricants are conveniently packaged for ease of application. Many of these products such as Astroglide Shooters have been pulled from the market due to FDA Medical Device Requirements. [25] Products containing benzocaine can numb all body parts with which they come in contact.

Organic or natural

In the United States, the first certified organic personal lubricant labeled with the USDA organic seal was Nude Personal Lubricant, [26] which was created in 2004 by Applied Organics. The US Food and Drug Administration (FDA) regulates lubricant as a medical device rather than as a cosmetic. Because of strict FDA guidelines for medical devices, organic personal lubricants were no longer allowed to carry a USDA seal, and they should be very careful about using the term organic anywhere on the label. Many of these types of lubricants also market themselves as "natural" and do not contain parabens, glycerin, diethanolamine (DEA) or animal-based ingredients. Some contain botanicals such as aloe vera or plant extracts.

Specialty lubricants

Warming lubricants contain specific ingredients to cause a sensation of warmth. Breathing on these types of lubricants may increase the effect. "Cooling" or "tingling" lubricants may contain ingredients such as peppermint. Some lubricants are sold together, such as "hot and cold", or are marketed for a specific use or effect. [27] Flavored lubricants contain flavorings, such as fruit flavors, to enhance oral contact. "Edible" lubricants may be flavored and/or may not contain any ingredients that are not advisable to eat.

Other

Other products that have been used as personal lubricants include vegetable shortening, which is durable and inexpensive but damaging to latex. [28] In a controversial scene in the movie Last Tango in Paris , the character Paul, played by Marlon Brando, uses butter during anal sex with the character Jeanne, played by Maria Schneider.

Uses

Sexual activity

A personal lubricant can be used to increase pleasure and reduce pain during sexual intercourse or other activities and may be used for lubricating the penis, vagina, anus, stroker, dildo or other sex toys before or during activity. Lubricant may be applied to any body part desired, to the inside and/or outside of condoms, or to the hands or fingers. Personal lubricants are particularly useful for intercourse when a partner experiences dryness or excessive contraction (tightness) of the vagina or anus. Anal sex generally requires more generous application of lubricant since the anus does not have natural lubrication sufficient for most sexual activity. [29]

Masturbation

While most males and females produce varying amounts of their own lubrication, extra lubrication is sometimes sought when needed. There are specific lubricants which may be used in male masturbation, often called "masturbation creams", but are not suitable for vaginal or anal use or for use with condoms. [30] Many men in Japan use lubricant created specifically for onaholes such as the Tenga Egg. [31] Lubricant that is safe for sexual intercourse is also safe for masturbation.

Hand lotion is often used for recreational masturbation and popularly seen as an alternative to lubricants created specifically for sexual intercourse. [32]

Medicine

Enema nozzles [33] [34] and rectal thermometer tips should be lubricated before use to minimize friction while inserting through the tightly retentive anal sphincter. [35]

Personal lubricants can help treat erectile dysfunction in older men. [36]

Risks

As of December 2012, the U.S. Food & Drug Administration does not typically require testing of personal lubricants in humans. [ citation needed ] The agency classifies them as medical devices, so testing occurs on animals such as rabbits and guinea pigs. Rectal use of lubricants is viewed by the agency as an off-label application. [ citation needed ] In 2012 it was reported that participants who consistently used personal lubricants for rectal intercourse had a higher prevalence of sexually transmitted infections (STI), such as chlamydia, than inconsistent users.[ citation needed ] Some warming lubricants have been shown to have an osmolality count more than 30 times the body's own fluid. Increased herpes transmission was more than ninefold when compared with animals not administered lubricant. In 2007 it was demonstrated that certain lubricants can cause significant damage to the rectal tissue of human study participants – major shedding of cells from tissue samples biopsied 60 to 90 minutes after lubricant application was observed. Certain lubricants containing the ingredient chlorhexidine, an antibacterial agent, has been shown to kill three species of Lactobacillus and has been shown to unbalance the natural flora in the vagina, which might lead to infections such as bacterial vaginosis. Lubricants with osmolalities closer to that of the body, such as agar-based lubes, did not damage the tissue samples or boost HIV infection rates. [37] [ citation needed ]

Some may experience irritation from the use of certain lubricants. Some lubricants (as mentioned above under Water-based) have been found to damage cells or even increase the replication of the HIV virus. [7] Nonoxynol-9, a spermicide contained in some lubricants, can destroy vaginal and rectum cell membranes which may increase the rate of STI transmission. [38] Spermicidally lubricated condoms do not contain enough spermicide to increase contraceptive effectiveness, [39] but application of separate spermicide is thought to reduce pregnancy rates significantly. [40]

Related Research Articles

Anal sex or anal intercourse is generally the insertion and thrusting of the erect penis into a person's anus, or anus and rectum, for sexual pleasure. Other forms of anal sex include anal fingering, the use of sex toys, anilingus, pegging, as well as electrostimulation and erotic torture such as figging. Although anal sex most commonly means penile–anal penetration, sources sometimes use anal intercourse to exclusively denote penile–anal penetration, and anal sex to denote any form of anal sexual activity, especially between pairings as opposed to anal masturbation.

<span class="mw-page-title-main">Condom</span> Device for birth control and STI prevention

A condom is a sheath-shaped barrier device used during sexual intercourse to reduce the probability of pregnancy or a sexually transmitted infection (STI). There are both external (male) and internal (female) condoms.

<span class="mw-page-title-main">Safe sex</span> Ways to reduce the risk of acquiring STIs

Safe sex is sexual activity using methods or contraceptive devices to reduce the risk of transmitting or acquiring sexually transmitted infections (STIs), especially HIV. "Safe sex" is also sometimes referred to as safer sex or protected sex to indicate that some safe sex practices do not eliminate STI risks. It is also sometimes used colloquially to describe methods aimed at preventing pregnancy that may or may not also lower STI risks.

<span class="mw-page-title-main">Butt plug</span> Sex toy that is designed to be inserted into the rectum

A butt plug is a sex toy that is designed to be inserted into the rectum for sexual pleasure. They are similar to a dildo in some ways but tend to be shorter and have a flanged end to prevent the device from being lost inside the rectum.

<span class="mw-page-title-main">K-Y Jelly</span> Personal lubricant

K-Y Jelly is a water-based, water-soluble personal lubricant, most commonly used as a lubricant for sexual intercourse and masturbation. A variety of different products and formulas are produced under the K-Y banner, some of which are not water-soluble.

<span class="mw-page-title-main">Prostate massage</span> Massage of the prostate gland via the rectum or perineum

Prostate massage is the massage or stimulation of the prostate gland for medical purposes or sexual stimulation.

<span class="mw-page-title-main">Nonoxynol-9</span> Chemical compound

Nonoxynol-9, sometimes abbreviated as N-9, is an organic compound that is used as a surfactant. It is a member of the nonoxynol family of nonionic surfactants. N-9 and related compounds are ingredients in various cleaning and cosmetic products. It is widely used in contraceptives for its spermicidal properties.

Spermicide is a contraceptive substance that destroys sperm, inserted vaginally prior to intercourse to prevent pregnancy. As a contraceptive, spermicide may be used alone. However, the pregnancy rate experienced by couples using only spermicide is higher than that of couples using other methods. Usually, spermicides are combined with contraceptive barrier methods such as diaphragms, condoms, cervical caps, and sponges. Combined methods are believed to result in lower pregnancy rates than either method alone.

<span class="mw-page-title-main">Anal beads</span> Sex toy

Anal beads are a sex toy consisting of multiple balls attached in series. Individual balls are continuously inserted through the anus into the rectum and then removed with varying speeds depending on the desired effect. The main use of anal beads are for sexual stimulation.

<span class="mw-page-title-main">Microbicides for sexually transmitted infections</span> Pharmacologic agents and chemical substances

Microbicides for sexually transmitted infections are pharmacologic agents and chemical substances that are capable of killing or destroying certain microorganisms that commonly cause sexually transmitted infection.

<span class="mw-page-title-main">Vaginal lubrication</span> Natural lubrication of the vagina during sexual arousal

Vaginal lubrication is a naturally produced fluid that lubricates the vagina. Vaginal lubrication is always present, but production increases significantly near ovulation and during sexual arousal in anticipation of sexual intercourse. Vaginal dryness is the condition in which this lubrication is insufficient, and sometimes artificial lubricants are used to augment it. Without sufficient lubrication, sexual intercourse can be painful. The vaginal lining has no glands, and therefore the vagina must rely on other methods of lubrication. Plasma from the vaginal walls due to vascular engorgement is considered to be the chief lubrication source, and the Bartholin's glands, located slightly below and to the left and right of the introitus, also secrete mucus to augment vaginal wall secretions. Near ovulation, cervical mucus provides additional lubrication.

Surgical lubricants, or medical lubricants, are substances used by health care providers to provide lubrication and lessen discomfort to the patient during certain medical and surgical procedures such as vaginal or rectal examinations. Some example of surgical compatible lubricants are:

<span class="mw-page-title-main">Female condom</span> Device for birth control and STI prevention

A female condom is a barrier device that is used during sexual intercourse as a barrier contraceptive to reduce the probability of pregnancy or sexually transmitted infection (STI). It is inserted in the vagina or anus before intercourse to reduce the risk of exposure to semen or other body fluids. The female condom was invented by Danish MD Lasse Hessel in 1990 and approved by the FDA for sale in the US in 1993.

<span class="mw-page-title-main">Semen analysis</span> Scientific analysis of semen

A semen analysis, also called seminogram or spermiogram, evaluates certain characteristics of a male's semen and the sperm contained therein. It is done to help evaluate male fertility, whether for those seeking pregnancy or verifying the success of vasectomy. Depending on the measurement method, just a few characteristics may be evaluated or many characteristics may be evaluated. Collection techniques and precise measurement method may influence results. The assay is also referred to as ejaculate analysis, human sperm assay (HSA), sperm function test, and sperm assay.

<span class="mw-page-title-main">Non-penetrative sex</span> Sexual activity that usually excludes penetration

Non-penetrative sex or outercourse is sexual activity that usually does not include sexual penetration. It generally excludes the penetrative aspects of vaginal, anal, or oral sex, but includes various forms of sexual and non-sexual activity, such as frottage, manual sex, mutual masturbation, kissing, or cuddling. Some forms of non-penetrative sex, particularly when termed outercourse, include penetrative aspects, such as penetration that may result from forms of fingering or oral sex.

<span class="mw-page-title-main">Artificial vagina</span> Device designed to imitate the female sex organs

An artificial vagina is a device designed to imitate the vagina as well as sometimes the vulva. To achieve this, it will generally be made of a soft material, lubricated, and occasionally heated.

A conception device is a medical device which is used to assist in the achievement of a pregnancy, often, but not always, by means other than sexual intercourse. This article deals exclusively with conception devices for human reproduction.

Wet Lubricants is a brand of personal lubricants produced by Wet International, part of Trigg Laboratories in Las Vegas. The line includes a variety of water-based and silicone-based lubricants, as well as massage oils and shaving creams.

A rectal microbicide is a microbicide for rectal use. Most commonly such a product would be a topical gel inserted into the anus so that it make act as protection against the contract of a sexually transmitted infection during anal sex.

One Male Condom is a natural rubber latex condom product specifically intended, evaluated and marketed for use during anal sex, as well as being approved for use as a contraceptive and to reduce the risk of sexually transmitted infections (STIs) by vaginal sex. It received US Food and Drug Administration (FDA) approval to be marketed for anal sex use on February 23, 2022. All previous FDA condom approvals were specifically only approvals for use with vaginal sex, and thus their use was off-label for anal sex. When used for anal sex, the One Male Condom product is intended to be used with a compatible water-based personal lubricant.

References

  1. "K-Y Jelly buyout could push up prices of lubricant, competition watchdog warns". TheGuardian.com . 22 May 2015.
  2. http://www.medline.com/catalog/category-products.jsp?iclp=Z05-CA10_08_05&N=106248&itemId=Z05-CA10_08_05&No=0 RET. DEC 28 2017 22:49
  3. Vesely, Rebecca (December 1, 2008). "Protecting Women from HIV--Docs Hopeful About Microbicides". Scientific American. Retrieved 6 December 2011.
  4. "Study finds most lubricants damage rectal cells and some increase HIV activity". aidsmap. Archived from the original on 16 May 2011. Retrieved 30 April 2011.
  5. Dezzutti, CS; Brown, ER; Moncla, B; Russo, J; Cost, M; et al. (2012). "Is Wetter Better? An Evaluation of Over-the-Counter Personal Lubricants for Safety and Anti-HIV-1 Activity". PLOS ONE. 7 (11): e48328. Bibcode:2012PLoSO...748328D. doi: 10.1371/journal.pone.0048328 . PMC   3492332 . PMID   23144863.
  6. "The Latex Condom: Recent Advances, Future Directions". FHI Network (Chapter 3: User Behaviors and Characteristics Related to Condom Failure ed.). Family Health International. 2010. Archived from the original on 2011-09-27. Retrieved 2010-06-29.
  7. 1 2 "Study finds most lubricants damage rectal cells and some increase HIV activity". AIDSMap. Archived from the original on 16 May 2011. Retrieved 30 April 2011.
  8. 1 2 "Personal Lubricant Help". Saturday, 4 May 2019
  9. 1 2 Practice Committee of the American Society for Reproductive Medicine in collaboration with the Society for Reproductive Endocrinology and Infertility. Optimizing natural fertility: a committee opinion" Fertil Steril 2013;100(3): 631–7.
  10. 1 2 Tulandi T, Plouffe L Jr, McInnes RA. Effect of saliva on sperm motility and activity" Fertil Steril 1982;38:721–3.
  11. 1 2 3 4 5 6 Anderson, L; Lewis, SE; McClure, N. (1998). "The effects of coital lubricants on sperm motility in vitro". Hum Reprod. 13 (12): 3351–6. doi:10.1093/humrep/13.12.3351. PMID   9886513.
  12. Practice Committee of the American Society for Reproductive Medicine in collaboration with the Society for Reproductive Endocrinology and Infertility. Optimizing natural fertility: a committee opinion" Fertil Steril 2013;100(3): 631–7
  13. 1 2 3 4 Frishman, GN; Luciano, AA; Maier, DB. (1992). "Evaluation of Astroglide, a new vaginal lubricant: effects of length of exposure and concentration on sperm motility". Fertil Steril. 58 (3): 630–2. doi:10.1016/S0015-0282(16)55279-0. PMID   1521661.
  14. 1 2 Miller, B; Klein, TA; Opsahl, MS. (1994). "The effect of a surgical lubricant on in vivo sperm penetration of cervical mucus". Fertil Steril. 61 (6): 1171–3. doi: 10.1016/S0015-0282(16)56778-8 . PMID   8194639.
  15. Mowat, A; Newton, C; Boothroyd, C; Demmers, K; Fleming, S (2014). "The effects of vaginal lubricants on sperm function: an in vitro analysis". Journal of Assisted Reproduction and Genetics. 31 (3): 333–9. doi:10.1007/s10815-013-0168-x. PMC   3947082 . PMID   24390681.
  16. 1 2 3 Agarwal, A; Deepinder, F; Cocuzza, M; Short, RA; Evenson, DP. (2008). "Effect of vaginal lubricants on sperm motility and chromatin integrity: a prospective comparative study". Fertil Steril. 89 (2): 375–9. doi: 10.1016/j.fertnstert.2007.02.050 . PMID   17509584.
  17. 1 2 3 Kutteh, WH; Chao, CH; Ritter, JO; Byrd, W. (1996). "Vaginal lubricants for the infertile couple: effect on sperm activity". Int J Fertil Menopausal Stud. 41 (4): 400–4. PMID   8894797.
  18. Ellington J, Daughtery S. Prevalence of vaginal dryness in trying-to-conceive couples" Fertil Steril 2003;79:21–2.
  19. 1 2 Demir, B; Dilbaz, B; Cinar, O; Karadag, B; Tasci, Y; Kocak, M; et al. (2011). "Factors affecting pregnancy outcome of intrauterine insemination cycles in couples with favourable female characteristics". J Obstet Gynaecol. 31 (5): 420–3. doi:10.3109/01443615.2011.569780. PMID   21627427. S2CID   11063970.
  20. 1 2 Vargas, J; Crausaz, M; Senn, A; Germond (2011). "nonspermicidal lubricant and ultrasound gels used in reproductive medicine". Fertil Steril. 95 (2): 835–6. doi: 10.1016/j.fertnstert.2010.09.011 . PMID   20971464.
  21. Ellington, J; Daughtery, S. (2003). "Prevalence of vaginal dryness in trying-to-conceive couples". Fertil Steril. 79: 21–2. doi: 10.1016/s0015-0282(03)00127-4 .
  22. Steiner, AZ; Long, DL; Tanner, C; Herring, AH (Jul 2012). "Effect of vaginal lubricants on natural fertility". Obstet Gynecol. 120 (1): 44–51. doi:10.1097/aog.0b013e31825b87ae. PMC   3427535 . PMID   22914390.
  23. Agarwal, A; Malvezzi, H; Sharma, R. (2013). "Effect of an isotonic lubricant on sperm collection and sperm quality". Fertil. Steril. 99 (6): 1581–6. doi: 10.1016/j.fertnstert.2013.01.116 . PMID   23490168.
  24. Mowat, A; Newton, C; Boothroyd, C; Demmers, K; Fleming, S (2014). "The effects of vaginal lubricants on sperm function: an in vitro analysis". J Assist Reprod Genet. 31 (3): 333–9. doi:10.1007/s10815-013-0168-x. PMC   3947082 . PMID   24390681.
  25. "CFR – Code of Federal Regulations Title 21". www.accessdata.fda.gov. Retrieved 2019-12-17.
  26. "Nude Personal Lubricant, Certified Organic by CCOF, Santa Cruz, California". slickn.com. Archived from the original on 13 February 2018. Retrieved 7 April 2018.
  27. "Sex-Life Road Test: Warming and Cooling Lubes". Red Book Magazine. 27 April 2007. Archived from the original on 12 November 2011. Retrieved 6 December 2011.
  28. Graham, Mark (2004). "Sexual Things". GLQ: A Journal of Lesbian and Gay Studies . 10 (2): 211–313. doi:10.1215/10642684-10-2-299. S2CID   201759576.
  29. "Personal Lubricants for Uninterrupted Pleasure". Lube Zone. 2016-01-18. Archived from the original on 2016-11-09. Retrieved 2016-11-08.
  30. Hauck, Tyler. "Lubricants for Sex: Oil-Based Lube". AskMen.com. Archived from the original on 2008-12-26. Retrieved 2008-12-07.
  31. "Inside, Robot".
  32. "Every Question You Have About Male Masturbation Habits, Answered". 20 August 2019.
  33. Aby Mitchell (2019-02-14). "Administering an enema: indications, types, equipment and procedure". The British Journal of Nursing . 28 (9). ISSN   2052-2819 . Retrieved 2023-08-17.
  34. "Soapsuds enema". Biology-Online Dictionary. Biology-Online. Retrieved 2023-08-17.
  35. Johns Hopkins School of Medicine (2019-07-28). "Measuring a Baby's Temperature". Health Home Conditions and Diseases. Johns Hopkins University. Archived from the original on 2019-11-03. Retrieved 2020-04-12.
  36. "HOW LUBRICANT CAN TRANSFORM YOUR SEX LIFE" . Independent.co.uk . 14 January 2019. Archived from the original on 2022-05-25.
  37. Wolf, Lauren K. "Studies Raise Questions About Safety Of Personal Lubricants – December 10, 2012 Issue – Vol. 90 Issue 50 – Chemical & Engineering News". cen.acs.org. Archived from the original on 9 January 2015. Retrieved 7 April 2018.
  38. Bass, Emily (August 2002). "Learning from microbicides: A young field's experience working with high-risk women". AIDScience. IAVI. Archived from the original on 2011-07-28. Retrieved 2008-12-07.
  39. "Birth Control – Nonoxynol-9 and Risk Reduction". Our Bodies Ourselves. Global Campaign for Microbicides. March 2005. Archived from the original on 2009-01-23. Retrieved 2008-12-07.
  40. Kestelman P, Trussell J (1991). "Efficacy of the simultaneous use of condoms and spermicides". Fam Plann Perspect. 23 (5): 226–7, 232. doi:10.2307/2135759. JSTOR   2135759. PMID   1743276.