Rachel McKendry

Last updated

Rachel McKendry
Rachel McKendry - 29858203981 (cropped) (cropped).jpg
Rachel McKendry in September 2016
Born
Rachel Anne McKendry
Alma mater Durham University (BSc)
University of Cambridge (PhD)
Awards Royal Society Wolfson Research Merit Award (2014)
Rosalind Franklin Award (2014)
Scientific career
Institutions University College London
Thesis Chemical force microscopy  (1999)
Academic advisorsTrevor Rayment and Chris Abell
Website iris.ucl.ac.uk/iris/browse/profile?upi=RMCKE57

Rachel Anne McKendry is a British chemist. She is Director of i-sense, a UK-based interdisciplinary research collaboration developing early warning sensing systems for infectious diseases, and was part of the UK's Cross Council Initiative on Antimicrobial Resistance. McKendry is also Professor of Biomedical Nanoscience at University College London, holding a joint appointment in the Division of Medicine and the London Centre for Nanotechnology.

Contents

Early life and education

McKendry studied chemistry at Durham University (Trevelyan College), graduating in 1994. She was awarded a PhD from the University of Cambridge [1] in 1999 and won a Girton College, Cambridge Research Fellowship in 1998. [2]

Career and research

After working as a postdoctoral researcher at the IBM Zurich Research Laboratory, McKendry returned to the UK to take up a Royal Society Dorothy Hodgkin Research Fellowship, and to work at University College London.

McKendry leads an interdisciplinary research team at the intersection of nanotechnology, telecommunications, big data, infectious diseases and public health. In 2015, she presented a Tedx Talk in Exeter on "The Digital Future of Public Health", in which she discussed early warning systems for disease outbreaks – from SARS to Ebola – being developed along the lines of Google Flu Trends, based on anonymised social media chatter from the world's many billion users of smartphones and other digital devices. [3]

She has published many research papers in Nature, Nature Nanotechnology, Nature Materials and Proceedings of the National Academy of Sciences USA.

Recent research highlights include nanodiamond quantum materials for ultra-sensitive virus detection, [4] cantilever nanosensors for phenotypic detection of antimicrobial resistance, [5] and deep learning to support quality assurance and decision support of rapid field-based tests. [6] McKendry also led a review of digital technologies in the global public health response to COVID-19. [7]

i-Sense EPSRC IRC

McKendry is Director [8] of i-Sense, a large interdisciplinary research collaboration set up in 2013 to develop early warning sensing systems for infectious diseases, and funded by the Engineering and Physical Sciences Research Council with a total investment of £11 million (renewed from 2018). [9]

Membership of panels

Awards and honours

In 2009 McKendry was awarded the Institute of Physics Clifford Paterson Medal and Prize. [14]

In 2014 she received a Royal Society Wolfson Research Merit Award, to assist her study of 'New Paradigms in Connected Global Health for Infectious Diseases.' [15]

In 2014 she received a Royal Society Rosalind Franklin Award for her "scientific achievements, her suitability as a role model and for her exciting proposal to launch a national competition to create mobile phone apps to inspire women to become leaders in science, technology, engineering and mathematics (STEM)". [16]

Related Research Articles

Nanomedicine is the medical application of nanotechnology. Nanomedicine ranges from the medical applications of nanomaterials and biological devices, to nanoelectronic biosensors, and even possible future applications of molecular nanotechnology such as biological machines. Current problems for nanomedicine involve understanding the issues related to toxicity and environmental impact of nanoscale materials.

Biodefense refers to measures to restore biosecurity to a group of organisms who are, or may be, subject to biological threats or infectious diseases. Biodefense is frequently discussed in the context of biowar or bioterrorism, and is generally considered a military or emergency response term.

<span class="mw-page-title-main">Stanley Falkow</span> American microbiologist

Stanley "Stan" Falkow was an American microbiologist and a professor of microbiology at Georgetown University, University of Washington, and Stanford University School of Medicine. Falkow is known as the father of the field of molecular microbial pathogenesis. He formulated molecular Koch's postulates, which have guided the study of the microbial determinants of infectious diseases since the late 1980s. Falkow spent over 50 years uncovering molecular mechanisms of how bacteria cause disease and how to disarm them. Falkow also was one of the first scientists to investigate antimicrobial resistance, and presented his research extensively to scientific, government, and lay audiences explaining the spread of resistance from one organism to another, now known as horizontal gene transfer, and the implications of this phenomenon on our ability to combat infections in the future.

The Health Protection Agency (HPA) was a non-departmental public body in the United Kingdom. It was set up by the UK government in 2003 to protect the public from threats to their health from infectious diseases and environmental hazards.

<span class="mw-page-title-main">Eric Topol</span> American cardiologist, scientist, and author (born 1954)

Eric Jeffrey Topol is an American cardiologist, scientist, and author. He is the founder and director of the Scripps Research Translational Institute, a professor of Molecular Medicine and Executive Vice-President at Scripps Research Institute, and a senior consultant at the Division of Cardiovascular Diseases at Scripps Clinic in La Jolla, California. He has published three bestseller books on the future of medicine: The Creative Destruction of Medicine (2010), The Patient Will See You Now (2015), and Deep Medicine: How Artificial Intelligence Can Make Healthcare Human Again (2019). He was commissioned by the UK from 2018–2019 to lead planning for the National Health Service's future workforce, integrating genomics, digital medicine, and artificial intelligence.

<span class="mw-page-title-main">Nanodiamond</span> Extremely small diamonds used for their thermal, mechanical and optoelectronic properties

Nanodiamonds, or diamond nanoparticles, are diamonds with a size below 100 nanometers. They can be produced by impact events such as an explosion or meteoritic impacts. Because of their inexpensive, large-scale synthesis, potential for surface functionalization, and high biocompatibility, nanodiamonds are widely investigated as a potential material in biological and electronic applications and quantum engineering.

The Center for Infectious Disease Research and Policy (CIDRAP) is a center within the University of Minnesota that focuses on addressing public health preparedness and emerging infectious disease response. It was founded in 2001 by Dr. Michael Osterholm, in order to "prevent illness and death from infectious diseases through epidemiological research and rapid translation of scientific information into real-world practical applications and solutions". It is not part of the Center for Disease Control or National Institute of Health.

<span class="mw-page-title-main">Jeremy Farrar</span> British medical researcher

Sir Jeremy James Farrar is a British medical researcher who has served as Chief Scientist at the World Health Organization since 2023. He was previously the director of The Wellcome Trust from 2013 to 2023 and a professor of tropical medicine at the University of Oxford.

<span class="mw-page-title-main">Genomics England</span> British company

Genomics England is a British company set up and owned by the United Kingdom Department of Health and Social Care to run the 100,000 Genomes Project. The project aimed in 2014 to sequence 100,000 genomes from NHS patients with a rare disease and their families, and patients with cancer. An infectious disease strand is being led by Public Health England.

The 100,000 Genomes Project is a now-completed UK Government project managed by Genomics England that is sequencing whole genomes from National Health Service patients. The project is focusing on rare diseases, some common types of cancer, and infectious diseases. Participants give consent for their genome data to be linked to information about their medical condition and health records. The medical and genomic data is shared with researchers to improve knowledge of the causes, treatment, and care of diseases. The project has received over £300 million from public and private investment.

<span class="mw-page-title-main">Ambika Bumb</span> American businesswoman and medical researcher

Ambika Bumb is an American biomedical scientist and businessperson. Bumb is a nanomedicine specialist who uses nanotechnology for the detection and treatment of disease. Her discoveries using nanodiamonds while working as postdoctoral researcher at the National Cancer Institute and the National Heart, Lung, and Blood Institute led to the launch of the biotech Bikanta. Bumb is currently Deputy Executive Director at the Bipartisan Commission on Biodefense.

Sharon Jayne Peacock is a British microbiologist who is Professor of Public Health and Microbiology in the Department of Medicine at the University of Cambridge. Peacock also sits on Cambridge University Council.

Health Innovation Manchester is an academic health science centre established in October 2017 to drive innovation in healthcare in Greater Manchester. It is closely associated with the Greater Manchester Health and Social Care Partnership.

<span class="mw-page-title-main">Caitlin Rivers</span> American epidemiologist

Caitlin M. Rivers is an American epidemiologist who as Senior Scholar at the Johns Hopkins Center for Health Security and assistant professor at the Johns Hopkins Bloomberg School of Public Health, specializing on improving epidemic preparedness. Rivers is currently working on the American response to the COVID-19 pandemic with a focus on the incorporation of infectious disease modeling and forecasting into public health decision making.

Allison Joan McGeer is a Canadian infectious disease specialist in the Sinai Health System, and a professor in the Department of Laboratory Medicine and Pathobiology at the University of Toronto. She also appointed at the Dalla Lana School of Public Health and a Senior Clinician Scientist at the Lunenfeld-Tanenbaum Research Institute, and is a partner of the National Collaborating Centre for Infectious Diseases. McGeer has led investigations into the severe acute respiratory syndrome outbreak in Toronto and worked alongside Donald Low. During the COVID-19 pandemic, McGeer has studied how SARS-CoV-2 survives in the air and has served on several provincial committees advising aspects of the Government of Ontario's pandemic response.

Alison Helen Holmes is a British infectious diseases specialist, who is a professor at Imperial College London and the University of Liverpool. Holmes serves as Director of the National Institute for Health Research (NIHR) Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance and Consultant at Hammersmith Hospital. Holmes is on the Executive Committee of the International Society of Infectious Diseases, and she serves on a variety of World Health Organization (WHO) expert groups related to antimicrobial use, Antimicrobial Resistance (AMR), infection prevention and sepsis. Her research considers how to mitigate antimicrobial resistance.

Eleni Nastouli is a Greek clinical virologist who works at University College London Hospitals NHS Foundation Trust (UCLH) and Great Ormond Street Hospital. At UCLH, Nastouli leads the Advanced Pathogen Diagnostics Unit, where she develops technologies for genome sequencing as well as studying how viruses are transmitted around hospitals. During the COVID-19 pandemic Nastouli led an investigation into infection rates amongst healthcare workers.

Ester H. Segal is an Israeli nanotechnology researcher and professor in the Department of Biotechnology and Food Engineering at the Technion - Israel Institute of Technology, where she heads the Laboratory for Multifunctional Nanomaterials. She is also affiliated with the Russell Berrie Nanotechnology Institute at the Technion - Israel Institute of Technology. Segal is a specialist in porous silicon nanomaterials, as well as nanocomposite materials for active packaging technologies to extend the shelf life of food.

Susan Hopkins CBE is an Irish epidemiologist and civil servant working in the UK. She is honorary clinical senior lecturer in the Department of Medicine at Imperial College London, and Chief Medical Advisor for the UK Health Security Agency (UKHSA).

References

  1. McKendry, Rachel Anne (1999). Chemical force microscopy. lib.cam.ac.uk (PhD thesis). University of Cambridge. OCLC   894601715. EThOS   uk.bl.ethos.624272.
  2. Cambridge University Reporter 5727 (4 February 1998). "Girton College". The Chancellor, Masters and Scholars of the University of Cambridge. Retrieved 7 December 2016.{{cite web}}: CS1 maint: numeric names: authors list (link)
  3. "Going viral: the digital future of public health".
  4. McKendry, Miller (2020). "Spin-enhanced nanodiamond biosensing for ultrasensitive diagnostics". Nature. 587 (7835): 588–593. doi:10.1038/s41586-020-2917-1. S2CID   227176732.
  5. Bennett, Isabel; Pyne, Alice L. B.; McKendry, Rachel A. (2020). "Cantilever sensors for rapid optical antimicrobial sensitivity testing". ACS Sensors. 5 (10): 3133–3139. doi:10.1021/acssensors.0c01216. PMC   7589985 . PMID   32900182.
  6. Turbé, Valérian; Herbst, Carina; Mngomezulu, Thobeka; Meshkinfamfard, Sepehr; Dlamini, Nondumiso; Mhlongo, Thembani; Smit, Theresa; Cherepanova, Valeriia; Shimada, Koki; Budd, Jobie; Arsenov, Nestor; Gray, Steven; Pillay, Deenan; Herbst, Kobus; Shahmanesh, Maryam; McKendry, Rachel A. (2021). "Deep learning of HIV field-based rapid tests". Nature Medicine. 27 (7): 1165–1170. doi:10.1038/s41591-021-01384-9. PMC   7611654 . PMID   34140702.
  7. Budd, Jobie; Miller, Benjamin S.; Manning, Erin M.; Lampos, Vasileios; Zhuang, Mengdie; Edelstein, Michael; Rees, Geraint; Emery, Vincent C.; Stevens, Molly M.; Keegan, Neil; Short, Michael J. (2020). "Digital technologies in the public-health response to COVID-19". Nature Medicine. 26 (8): 1183–1192. doi: 10.1038/s41591-020-1011-4 . hdl: 10044/1/85462 . ISSN   1546-170X.
  8. "Professor Rachel McKendry". i-sense.org.uk. Retrieved 31 October 2020.
  9. "About us". www.i-sense.org.uk. Retrieved 31 October 2020.
  10. "Tackling AMR – A Cross Council Initiative". Medical Research Council. Retrieved 9 December 2016.
  11. "IDRN". IDRN. 2009. Retrieved 7 December 2016.
  12. "Wide-area biological detection: Blackett review". gov.uk. Government Office for Science. 11 February 2014. Retrieved 7 December 2016.
  13. "The Topol Review". NHS Health Education England. February 2019. p. 92. Retrieved 10 November 2021.
  14. "2009 Paterson medal and prize". Institute of Physics. Retrieved 22 December 2019.
  15. "Royal Society Wolfson Merit Awards 2014".
  16. "Rachel McKendry Wins Royal Society Rosalind Franklin Award 2014". London Centre for Nanotechology. 5 August 2014. Retrieved 7 December 2016.