Radical perineal prostatectomy

Last updated
Radical perineal prostatectomy
Prostatelead.jpg
Location of prostate gland
Specialty Urology

Radical perineal prostatectomy is a surgical procedure wherein the entire prostate gland is removed through an incision in the area between the anus and the scrotum (perineum). [1] [2]

Contents

It is used to remove early prostate cancer, in select people who have a small well defined cancer in the prostate. It is less commonly used than the alternative methods of the retropubic route, or the robot assisted laparoscopic approach. [3] [4]

When the cancer is small and confined to the prostate, radical perineal prostatectomy achieves the same rate of cure as the retropubic approach but less blood is lost and recovery is faster. One downside to the perineal approach is an increased risk of fecal incontinence. [2] [5]

The procedure was first performed in 1904 by Hugh H. Young and assisted by William S. Halstead, as a way of removing the prostate in cancer treatment.[ citation needed ]

Uses

Radical perineal prostatectomy is used to remove early prostate cancer, in select people who have a small well defined cancer in the prostate. [3] It is less commonly used than the alternative methods of the retropubic route, or the robot assisted laparoscopic approach. [1] [4]

It is more suited to younger men, age under 70 years, who have at least a ten-year life expectancy, few if any other medical problems, a Gleason score of less than 8 (4+4) and PSA of less than 10. [3] It may be indicated where the man with prostate cancer is obese, has had several abdominal operations before, previous pelvic arterial bypass grafts or has a delayed recurrence of prostate cancer after salvage prostatectomy and radiotherapy. [3]

Technique

Diagram showing before and after a radical prostatectomy Diagram showing before and after a radical prostatectomy CRUK 473.svg
Diagram showing before and after a radical prostatectomy

Before surgery

Before the operation, an assessment of life expectancy is made. Physical examination including a digital rectal examination and routine blood tests are carried out. At least six transrectal ultrasound guided biopsies taken from different zones of the prostate are usually obtained. Other considerations include bowel preparation the day before surgery and taking antibiotics. [3]

Procedure

A radical perineal prostatectomy uses an incision in the area between the anus and the scrotum (perineum). [2] [6] There is more than one way of performing the procedure. [7] In men with normal erections, a small cancer which can not be felt and Gleason scores of 6 or less, it may be possible to preserve the nerves for erection. [7] The procedure usually takes around one hour. [4]

After surgery

Over the course of the first day or two after the procedure, many men require a gradual transfer from oral fluids to soft foods. Additionally, men are encouraged to maintain mobility and painkillers may be necessary initially but tapered off over time. The hospital stay is usually short and the Foley catheter can be removed usually at three weeks after surgery. Longer term followup with PSA monitoring is required. [3]

Complications and outcomes

Lymph nodes can be sampled through the same incision, although this procedure is not common place in the U.S. at this time. When the cancer is small and confined to the prostate, radical perineal prostatectomy achieves the same rate of cure as the retropubic approach but less blood is lost and recovery is faster. One downside to the perineal approach is an increased risk of fecal incontinence. [2] [5]

History

The procedure was first performed on a 70-year old married preacher on 7 April 1904 by American surgeon Hugh H. Young and assisted by William S. Halstead, as a way of removing the prostate in cancer treatment, after prostatic massage and an early type of transurethral resection of the prostate had failed to relieve him of pain in his urethra. [8] By 1937, Young reported a five-year survival rate of 50%. However, by the time the diagnosis of prostate cancer was made, it was usually too late to perform the procedure. [2] [9]

Removing the prostate via the perineal route went out of favour in the 1970s. However, with the introduction the PSA test, better public awareness of options for treating localised disease, the ability to perform nerve-sparing surgery, and the advantage of there being potentially less post-operative complications using the perineal route, rekindled interest in the procedure. [3]

Related Research Articles

<span class="mw-page-title-main">Prostate</span> Gland of the male reproductive system in most mammals

The prostate is both an accessory gland of the male reproductive system and a muscle-driven mechanical switch between urination and ejaculation. It is found in all male mammals. It differs between species anatomically, chemically, and physiologically. Anatomically, the prostate is found below the bladder, with the urethra passing through it. It is described in gross anatomy as consisting of lobes and in microanatomy by zone. It is surrounded by an elastic, fibromuscular capsule and contains glandular tissue, as well as connective tissue.

<span class="mw-page-title-main">Prostate cancer</span> Male reproductive organ cancer

Prostate cancer is the uncontrolled growth of cells in the prostate, a gland in the male reproductive system just below the bladder. Early prostate cancer usually causes no symptoms. As the tumor grows, it can damage nearby organs causing erectile dysfunction, blood in the urine or semen, and trouble urinating. Some tumors eventually spread to other areas of the body, particularly the bones and lymph nodes. There, tumors cause severe bone pain, leg weakness or paralysis, and eventually death.

<span class="mw-page-title-main">Episiotomy</span> Surgical incision of the perineum and the posterior vaginal wall

Episiotomy, also known as perineotomy, is a surgical incision of the perineum and the posterior vaginal wall generally done by a midwife or obstetrician. This is usually performed during second stage of labor to quickly enlarge the aperture allowing the baby to pass through. The incision, which can be done from the posterior midline of the vulva straight toward the anus or at an angle to the right or left, is performed under local anesthetic, and is sutured after delivery.

<span class="mw-page-title-main">Rectal prolapse</span> Medical condition

A rectal prolapse occurs when walls of the rectum have prolapsed to such a degree that they protrude out of the anus and are visible outside the body. However, most researchers agree that there are 3 to 5 different types of rectal prolapse, depending on whether the prolapsed section is visible externally, and whether the full or only partial thickness of the rectal wall is involved.

<span class="mw-page-title-main">Colorectal surgery</span> Field in medicine for disabilities in the rectum

Colorectal surgery is a field in medicine dealing with disorders of the rectum, anus, and colon. The field is also known as proctology, but this term is now used infrequently within medicine and is most often employed to identify practices relating to the anus and rectum in particular. The word proctology is derived from the Greek words πρωκτός proktos, meaning "anus" or "hindparts", and -λογία -logia, meaning "science" or "study".

An abdomino perineal resection, formally known as abdominoperineal resection of the rectum and abdominoperineal excision of the rectum is a surgery for rectal cancer or anal cancer. It is frequently abbreviated as AP resection, APR and APER.

<span class="mw-page-title-main">Cystectomy</span> Surgical removal of all or part of the bladder

Cystectomy is a medical term for surgical removal of all or part of the urinary bladder. It may also be rarely used to refer to the removal of a cyst. The most common condition warranting removal of the urinary bladder is bladder cancer.

<span class="mw-page-title-main">Prostatectomy</span> Surgical removal of all or part of the prostate gland

Prostatectomy is the surgical removal of all or part of the prostate gland. This operation is done for benign conditions that cause urinary retention, as well as for prostate cancer and for other cancers of the pelvis.

<span class="mw-page-title-main">Pelvic exenteration</span> Surgical removal of all pelvic organs

Pelvic exenteration is a radical surgical treatment that removes all organs from a person's pelvic cavity. It is used to treat certain advanced or recurrent cancers. The urinary bladder, urethra, rectum, and anus are removed. In women, the vagina, cervix, uterus, Fallopian tubes, ovaries and, in some cases, the vulva are removed. In men, the prostate is removed. The procedure leaves the person with a permanent colostomy and urinary diversion.

<span class="mw-page-title-main">Radical retropubic prostatectomy</span>

Radical retropubic prostatectomy is a surgical procedure in which the prostate gland is removed through an incision in the abdomen. It is most often used to treat individuals who have early prostate cancer. Radical retropubic prostatectomy can be performed under general, spinal, or epidural anesthesia and requires blood transfusion less than one-fifth of the time. Radical retropubic prostatectomy is associated with complications such as urinary incontinence and impotence, but these outcomes are related to a combination of individual patient anatomy, surgical technique, and the experience and skill of the surgeon.

<span class="mw-page-title-main">Defecography</span> Visualisation of the mechanics of a patients defecation

Defecography is a type of medical radiological imaging in which the mechanics of a patient's defecation are visualized in real time using a fluoroscope. The anatomy and function of the anorectum and pelvic floor can be dynamically studied at various stages during defecation.

<span class="mw-page-title-main">Laparoscopic radical prostatectomy</span>

Laparoscopic radical prostatectomy (LRP) is a form of radical prostatectomy, an operation for prostate cancer. Contrasted with the original open form of the surgery, it does not make a large incision but instead uses fiber optics and miniaturization.

Nerve-sparing surgery is a type of surgery that attempts to save the nerves near the tissues being removed.

<span class="mw-page-title-main">Prostate brachytherapy</span> Radiation therapy technique for the treatment of cancer

Brachytherapy is a type of radiotherapy, or radiation treatment, offered to certain cancer patients. There are two types of brachytherapy – high dose-rate (HDR) and low dose-rate (LDR). LDR brachytherapy is the one most commonly used to treat prostate cancer. It may be referred to as 'seed implantation' or it may be called 'pinhole surgery'.

<span class="mw-page-title-main">Ashutosh Tewari</span> American urologist, oncologist

Ashutosh K. Tewari is the chairman of urology at the Icahn School of Medicine at Mount Sinai Hospital in New York City. He is a board certified American urologist, oncologist, and principal investigator. Before moving to the Icahn School of Medicine in 2013, he was the founding director of both the Center for Prostate Cancer at Weill Cornell Medical College and the LeFrak Center for Robotic Surgery at NewYork–Presbyterian Hospital. Dr. Tewari was the Ronald P. Lynch endowed Chair of Urologic Oncology and the hospital's Director of Robotic Prostatectomy, treating patients with prostate, urinary bladder and other urological cancers. He is the current President of the Society for Urologic Robotic Surgeons (SURS) and the Committee Chair of the Prostate Program. Dr. Tewari is a world leading urological surgeon, and has performed over 10,000 robotically assisted procedures using the da Vinci Surgical System. Academically, he is recognized as a world-renowned expert on urologic oncology with over 250 peer reviewed published papers to his credit; he is on such lists as America's Top Doctors, New York Magazine's Best Doctors, and Who's Who in the World. In 2012, he was given the American Urological Association Gold Cystoscope Award for "outstanding contributions to the field of urologic oncology, most notably the treatment of prostate cancer and the development of novel techniques to improve the outcomes of robotic prostatectomy."

<span class="mw-page-title-main">Human anus</span> External opening of the rectum

In humans, the anus is the external opening of the rectum, located inside the intergluteal cleft and separated from the genitals by the perineum. Two sphincters control the exit of feces from the body during an act of defecation, which is the primary function of the anus. These are the internal anal sphincter and the external anal sphincter, which are circular muscles that normally maintain constriction of the orifice and which relaxes as required by normal physiological functioning. The inner sphincter is involuntary and the outer is voluntary. It is located behind the perineum which is located behind the vagina or scrotum.

Treatment for prostate cancer may involve active surveillance, surgery, radiation therapy – including brachytherapy and external-beam radiation therapy, proton therapy, high-intensity focused ultrasound (HIFU), cryosurgery, hormonal therapy, chemotherapy, or some combination. Treatments also extend to survivorship based interventions. These interventions are focused on five domains including: physical symptoms, psychological symptoms, surveillance, health promotion and care coordination. However, a published review has found only high levels of evidence for interventions that target physical and psychological symptom management and health promotion, with no reviews of interventions for either care coordination or surveillance. The favored treatment option depends on the stage of the disease, the Gleason score, and the PSA level. Other important factors include the man's age, his general health, and his feelings about potential treatments and their possible side-effects. Because all treatments can have significant side-effects, such as erectile dysfunction and urinary incontinence, treatment discussions often focus on balancing the goals of therapy with the risks of lifestyle alterations.

<span class="mw-page-title-main">Perineoplasty</span>

Perineoplasty denotes the plastic surgery procedures used to correct clinical conditions of the vagina and the anus. Among the vagino-anal conditions resolved by perineoplasty are vaginal looseness, vaginal itching, damaged perineum, fecal incontinence, genital warts, dyspareunia, vaginal stenosis, vaginismus, vulvar vestibulitis, and decreased sexual sensation. Depending upon the vagino-anal condition to be treated, there are two variants of the perineoplasty procedure: the first, to tighten the perineal muscles and the vagina; the second, to loosen the perineal muscles.

<span class="mw-page-title-main">Roger Kirby</span> British surgeon

Roger Sinclair Kirby FRCS(Urol), FEBU is a British retired prostate surgeon and professor of urology, researcher, writer on men's health and prostate disease, founding editor of the journal Prostate Cancer and Prostatic Diseases and Trends in Urology and Men's Health and a fundraiser for prostate disease charities, best known for his use of the da Vinci surgical robot for laparoscopic prostatectomy in the treatment of prostate cancer. He is a co-founder and president of the charity The Urology Foundation (TUF), vice-president of the charity Prostate Cancer UK, trustee of the King Edward VII's Hospital and as of 2020 is president of the Royal Society of Medicine (RSM), London.

<span class="mw-page-title-main">Vipul Patel</span>

Vipul R. Patel, FACS is the founder and Medical Director of the Florida Hospital Global Robotics Institute, founder and Vice President of the Society of Robotic Surgery, and founder and Editor Emeritus of The Journal of Robotic Surgery. He is board certified by the American Urological Association and specializes in robotic surgery for prostate cancer. As of February, 2018 he performed his 11,000th robotic-assisted prostatectomy. The large volume of prostatectomies he has performed has enabled him to amass a large amount of statistical evidence regarding the efficacy of robotic techniques which has been used in developing and refining techniques. Patel credits the use of robotic assisted surgery with helping surgeons achieve better surgical outcomes with the "trifecta" of cancer control, continence and sexual function. In the course of his career Patel has led and participated in studies that have resulted in developing improved outcomes for robotic surgery and urologic treatment.

References

  1. 1 2 Kirby, R. S.; Patel, M. I.; Poon, D. M. C. (2020). "Management of clinically localised disease". Fast Facts: Prostate Cancer: If, when and how to intervene. Karger Medical and Scientific Publishers. p. 69. ISBN   978-3-318-06587-9.
  2. 1 2 3 4 5 Korman, Howard J. (3 November 2020). "Radical Perineal Prostatectomy for Prostate Cancer: Practice Essentials, Technical Considerations, Outcomes". www.medscape.com. Medscape. Archived from the original on 7 February 2021. Retrieved 19 February 2021.
  3. 1 2 3 4 5 6 7 Sullivan L.D. (2003) Radical Perineal Prostatectomy. In: Bruskewitz R.C. (eds) Atlas of the Prostate. Current Medicine Group, London. https://doi.org/10.1007/978-1-4615-6505-5_10
  4. 1 2 3 Zippe C.D. (2006) Radical Perineal Prostatectomy. In: Novick A.C. et al. (eds) Operative Urology at the Cleveland Clinic. Humana Press. https://doi.org/10.1007/978-1-59745-016-4_37
  5. 1 2 Eden, Christopher; Hutton, Anthony (2013). "56. Laparoscopic radical prostatectomy". In Tewari, Ashutosh (ed.). Prostate Cancer: A Comprehensive Perspective. Springer. p. 679. ISBN   978-1-4471-2863-2.
  6. "radical perineal prostatectomy". www.cancer.gov. 2 February 2011. Retrieved 19 February 2021.
  7. 1 2 Korman, Howard (8 July 2020). "Radical Perineal Prostatectomy for Prostate Cancer Technique: Approach Considerations, Perineal Approach to Radical Prostatectomy, Postoperative Care". emedicine.medscape.com. Medscape. Archived from the original on 19 February 2021. Retrieved 19 February 2021.
  8. "Radical Prostatectomy | The British Association of Urological Surgeons Limited". www.baus.org.uk. Retrieved 19 February 2021.
  9. Shimkin, Michael B. (1977). Contrary to Nature: Being an Illustrated Commentary on Some Persons and Events of Historical Importance in the Development of Knowledge Concerning ... Cancer. U.S. Department of Health, Education, and Welfare, Public Health Service, National Institutes of Health. p. 265. ISBN   9780719400124.

Further reading