Gastroenterology is the branch of medicine focused on the digestive system and its disorders. The digestive system consists of the gastrointestinal tract, sometimes referred to as the GI tract, which includes the esophagus, stomach, small intestine and large intestine as well as the accessory organs of digestion which include the pancreas, gallbladder, and liver.
Crohn's disease is a type of inflammatory bowel disease (IBD) that may affect any segment of the gastrointestinal tract. Symptoms often include abdominal pain, diarrhea, fever, abdominal distension, and weight loss. Complications outside of the gastrointestinal tract may include anemia, skin rashes, arthritis, inflammation of the eye, and fatigue. The skin rashes may be due to infections as well as pyoderma gangrenosum or erythema nodosum. Bowel obstruction may occur as a complication of chronic inflammation, and those with the disease are at greater risk of colon cancer and small bowel cancer.
Ulcerative colitis (UC) is one of the two types of inflammatory bowel disease (IBD), with the other type being Crohn's disease. It is a long-term condition that results in inflammation and ulcers of the colon and rectum. The primary symptoms of active disease are abdominal pain and diarrhea mixed with blood (hematochezia). Weight loss, fever, and anemia may also occur. Often, symptoms come on slowly and can range from mild to severe. Symptoms typically occur intermittently with periods of no symptoms between flares. Complications may include abnormal dilation of the colon (megacolon), inflammation of the eye, joints, or liver, and colon cancer.
Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder characterized by a group of symptoms that commonly include abdominal pain, abdominal bloating and changes in the consistency of bowel movements. These symptoms may occur over a long time, sometimes for years. IBS can negatively affect quality of life and may result in missed school or work or reduced productivity at work. Disorders such as anxiety, major depression, and chronic fatigue syndrome are common among people with IBS.
Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine, with Crohn's disease and ulcerative colitis (UC) being the principal types. Crohn's disease affects the small intestine and large intestine, as well as the mouth, esophagus, stomach and the anus, whereas UC primarily affects the colon and the rectum.
Colitis is swelling or inflammation of the large intestine (colon). Colitis may be acute and self-limited or long-term. It broadly fits into the category of digestive diseases.
The Rome process and Rome criteria are an international effort to create scientific data to help in the diagnosis and treatment of functional gastrointestinal disorders, such as irritable bowel syndrome, functional dyspepsia and rumination syndrome. The Rome diagnostic criteria are set forth by Rome Foundation, a not for profit 501(c)(3) organization based in Raleigh, North Carolina, United States.
Dysbiosis is characterized by a disruption to the microbiome resulting in an imbalance in the microbiota, changes in their functional composition and metabolic activities, or a shift in their local distribution. For example, a part of the human microbiota such as the skin flora, gut flora, or vaginal flora, can become deranged, with normally dominating species underrepresented and normally outcompeted or contained species increasing to fill the void. Similar to the human gut microbiome, diverse microbes colonize the plant rhizosphere, and dysbiosis in the rhizosphere, can negatively impact plant health. Dysbiosis is most commonly reported as a condition in the gastrointestinal tract or plant rhizosphere.
Michael John Godfrey Farthing is British emeritus professor at the University of Sussex, where he was previously its vice-chancellor (2007–2016). His early academic career was in medicine, specialising in gastroenterology.
UCLPartners is an academic health science centre located in London, England. It is the largest academic health science centre in the world, treats more than 1.5 million patients each year, has a combined annual turnover of around £2 billion and includes around 3,500 scientists, senior researchers and consultants.
The Oxford Handbook of Clinical Medicine is a pocket textbook aimed at medical students and junior doctors, and covers all aspects of clinical medicine. It is published by Oxford University Press, and is available in print format and online. First published in 1985, it is now in its tenth edition, which was released in July 2017.
Janusz Jankowski is a doctor, educationalist and scientist of Scottish Polish origin He is an expert in Social and Healthcare Policy, Academic Management and Global Research and Education Networks He was formerly in previous senior management roles including Deputy Vice Chancellor of Research and Innovation, Pro Vice Chancellor Research, Vice Dean Research and the Sir James Black Professorship. He is father to three children, including son and amateur hockey player Jakob Jankowski.
Lloyd Mayer was an American gastroenterologist and immunologist. He was Professor and Co-Director of the Immunology institute at the Mount Sinai Medical Center, now known as the Marc and Jennifer Lipschultz Precision Immunology Institute.
Dame Parveen June Kumar is a British doctor who is currently Professor of Medicine and Education at Barts and The London School of Medicine and Dentistry. She worked in the NHS for over 40 years as a consultant gastroenterologist and physician at Barts and the London Hospitals and the Homerton University Hospital. She was the President of the British Medical Association in 2006, of the Royal Society of Medicine from 2010 to 2012, of the Medical Women's Federation from 2016 to 2018 and of the Royal Medical Benevolent Fund from 2013 to 2020. She was also Vice President of the Royal College of Physicians from 2003 to 2005. In addition, she was a founding non-executive director of the National Institute of Clinical Excellence, chaired the Medicines Commission UK until 2005, and also chaired the BUPA Foundation Charity for Research until 2013.
Suranjith Seneviratne is a doctor from Sri Lanka who practices in allergology and immunology.
Professor Jonathan Samuel Friedland is a British physician and medical researcher who is Deputy Vice-Chancellor and Professor of Infectious Diseases at St George's, University of London.
Rosemary Jane Boyton is a British immunologist who is Head of Lung Immunology and Adult Infectious Disease at Imperial College London. She works on the molecular immunology of infectious, allergic and autoimmune inflammation. She holds an honorary consultant position at the Royal Brompton Hospital, where she specialises in lung infection.
The MRC Weatherall Institute of Molecular Medicine at the University of Oxford is a research institute located at the John Radcliffe Hospital in Oxford. Founded in 1989 by Sir David Weatherall, the institute focuses on furthering our understanding of clinical medicine at a molecular level. It was one of the first institutes of its kind in the world to be dedicated to research in this area.
Shomron Ben-Horin is an Israeli physician, a co-founder & Chief Medical Officer of Evinature, and professor of medicine at the Tel-Aviv University.
Alan Desmond is an Irish consultant gastroenterologist and writer known for his advocacy of plant-based nutrition.
