SLC27A6

Last updated
SLC27A6
Identifiers
Aliases SLC27A6 , ACSVL2, FACVL2, FATP6, VLCS-H1, solute carrier family 27 member 6
External IDs OMIM: 604196 MGI: 3036230 HomoloGene: 38385 GeneCards: SLC27A6
Gene location (Human)
Ideogram human chromosome 5.svg
Chr. Chromosome 5 (human) [1]
Human chromosome 5 ideogram.svg
HSR 1996 II 3.5e.svg
Red rectangle 2x18.png
Band 5q23.3Start128,538,013 bp [1]
End129,033,642 bp [1]
RNA expression pattern
PBB GE SLC27A6 219932 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001017372
NM_014031
NM_001317984

NM_001081072

RefSeq (protein)

NP_001017372
NP_001304913
NP_054750

NP_001074541

Location (UCSC) Chr 5: 128.54 – 129.03 Mb Chr 18: 58.56 – 58.61 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Long-chain fatty acid transport protein 6 is a protein that in humans is encoded by the SLC27A6 gene. [5] [6] [7]

Contents

This gene encodes a member of the fatty acid transport protein family (FATP). FATPs are involved in the uptake of long-chain fatty acids and have unique expression patterns. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [7]

See also

Related Research Articles

ACSL6 protein-coding gene in the species Homo sapiens

Acyl-CoA synthetase long-chain family member 6 is an enzyme that in humans is encoded by the ACSL6 gene. Long-chain acyl-CoA synthetases such as ACSL6, catalyze the formation of acyl-CoA from fatty acids, ATP, and CoA.

ACSL1 protein-coding gene in the species Homo sapiens

Long-chain-fatty-acid—CoA ligase 1 is an enzyme that in humans is encoded by the ACSL1 gene.

ACSL5 protein-coding gene in the species Homo sapiens

Long-chain-fatty-acid—CoA ligase 5 is an enzyme that in humans is encoded by the ACSL5 gene.

ACSL3 protein-coding gene in the species Homo sapiens

Long-chain-fatty-acid—CoA ligase 3 is an enzyme that in humans is encoded by the ACSL3 gene.

Proton-coupled amino acid transporter 1 protein-coding gene in the species Homo sapiens

Proton-coupled amino acid transporter 1 is a protein that in humans is encoded by the SLC36A1 gene.

Y+L amino acid transporter 1 protein-coding gene in the species Homo sapiens

Y+L amino acid transporter 1 is a protein that in humans is encoded by the SLC7A7 gene.

Large neutral amino acids transporter small subunit 2 protein-coding gene in the species Homo sapiens

Large neutral amino acids transporter small subunit 2 is a protein that in humans is encoded by the SLC7A8 gene.

ACOT2 protein-coding gene in the species Homo sapiens

Acyl-CoA thioesterase 2, also known as ACOT2, is an enzyme which in humans is encoded by the ACOT2 gene.

Very long-chain acyl-CoA synthetase protein-coding gene in the species Homo sapiens

Very long-chain acyl-CoA synthetase is an enzyme that in humans is encoded by the SLC27A2 gene.

Long-chain fatty acid transport protein 4 protein-coding gene in the species Homo sapiens

Long-chain fatty acid transport protein 4 is a protein that in humans is encoded by the SLC27A4 gene. This membrane protein is also called FATP4 or ACSVL5. The purified protein shows enzyme activity, esterifying long and very long chain fatty acids with Coenzyme A. It is debated whether it is also a fatty acid transporter at the plasma membrane.

ACSBG1 protein-coding gene in the species Homo sapiens

Acyl-CoA Synthetase, Bubblegum Family, member 1 (ACSBG1) is an enzyme that in humans is encoded by the ACSBG1 gene.

ACOT4 protein-coding gene in the species Homo sapiens

Acyl-coenzyme A thioesterase 4 is an enzyme that in humans is encoded by the ACOT4 gene.

ACOT11 protein-coding gene in the species Homo sapiens

Acyl-coenzyme A thioesterase 11 also known as StAR-related lipid transfer protein 14 (STARD14) is an enzyme that in humans is encoded by the ACOT11 gene. This gene encodes a protein with acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates which relies on its StAR-related lipid transfer domain. Expression of a similar murine protein in brown adipose tissue is induced by cold exposure and repressed by warmth. Expression of the mouse protein has been associated with obesity, with higher expression found in obesity-resistant mice compared with obesity-prone mice. Alternative splicing results in two transcript variants encoding different isoforms.

ACOX3 protein-coding gene in the species Homo sapiens

Peroxisomal acyl-coenzyme A oxidase 3 is an enzyme that in humans is encoded by the ACOX3 gene.

SLC27A5 protein-coding gene in the species Homo sapiens

Bile acyl-CoA synthetase is an enzyme that in humans is encoded by the SLC27A5 gene.

ACSM2B protein-coding gene in the species Homo sapiens

Acyl-coenzyme A synthetase ACSM2B, mitochondrial is an enzyme that in humans is encoded by the ACSM2B gene.

Long-chain fatty acid transport protein 1 protein-coding gene in the species Homo sapiens

Long-chain fatty acid transport protein 1 (FATP1) is a protein that in humans is encoded by the SLC27A1 gene.

SLC27A3 protein-coding gene in the species Homo sapiens

Long-chain fatty acid transport protein 3 is a protein that in humans is encoded by the SLC27A3 gene.

SLC6A18 protein-coding gene in the species Homo sapiens

Solute carrier family 6, member 18 also known as SLC6A18 is a protein which in humans is encoded by the SLC6A18 gene.

ACOT13 protein-coding gene in the species Homo sapiens

Acyl-CoA thioesterase 13 is a protein that in humans is encoded by the ACOT13 gene. This gene encodes a member of the thioesterase superfamily. In humans, the protein co-localizes with microtubules and is essential for sustained cell proliferation.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000113396 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000024600 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Gimeno RE, Ortegon AM, Patel S, Punreddy S, Ge P, Sun Y, Lodish HF, Stahl A (Apr 2003). "Characterization of a heart-specific fatty acid transport protein". J Biol Chem. 278 (18): 16039–44. doi: 10.1074/jbc.M211412200 . PMID   12556534.
  6. Steinberg SJ, Wang SJ, McGuinness MC, Watkins PA (Oct 1999). "Human liver-specific very-long-chain acyl-coenzyme A synthetase: cDNA cloning and characterization of a second enzymatically active protein". Mol Genet Metab. 68 (1): 32–42. doi:10.1006/mgme.1999.2883. PMID   10479480.
  7. 1 2 "Entrez Gene: SLC27A6 solute carrier family 27 (fatty acid transporter), member 6".

Further reading