SYNPR

SYNPR
Identifiers
Aliases	SYNPR , SPO, synaptoporin
External IDs	MGI: 1919253 HomoloGene: 11407 GeneCards: SYNPR
Gene location (Human)
Chr.	Chromosome 3 (human)
End	63,616,924 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	9,184,983 bp
RNA expression pattern
	Top expressed in
	cerebellar vermis; ; nucleus accumbens; ; external globus pallidus; ; Brodmann area 46; ; middle temporal gyrus; ; caudate nucleus; ; cerebellar hemisphere; ; superior frontal gyrus; ; Brodmann area 23; ; putamen;
	Top expressed in
	habenula; ; olfactory tubercle; ; dorsomedial hypothalamic nucleus; ; dentate gyrus; ; nucleus accumbens; ; globus pallidus; ; suprachiasmatic nucleus; ; cerebellar vermis; ; piriform cortex; ; hippocampus proper;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding ; syntaxin-1 binding ;
Cellular component	synapse ; membrane ; cell junction ; cytoplasmic vesicle ; integral component of synaptic vesicle membrane ; synaptic vesicle membrane ; neuron projection ; integral component of membrane ; synaptic vesicle ;
Biological process	transport ;
	Sources:Amigo / QuickGO
Orthologs
	132204
	72003
	ENSG00000163630
	ENSMUSG00000056296
	Q8TBG9
	Q8BGN8
	NM_001130003 ; NM_144642
	NM_001163032 ; NM_028052
	NP_001123475 ; NP_653243
	NP_001156504 ; NP_082328
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated August 19, 2023

Synaptoporin is a protein that in humans is encoded by the SYNPR gene.^[5]^[6]^[7]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000163630 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000056296 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Leube RE (Aug 1994). "Expression of the synaptophysin gene family is not restricted to neuronal and neuroendocrine differentiation in rat and human". Differentiation. 56 (3): 163–71. doi:10.1046/j.1432-0436.1994.5630163.x. PMID 8034131.
↑ Dai J, Ji C, Gu S, Wu Q, Wang L, Xu J, Zeng L, Ye X, Yin G, Xie Y, Mao Y (Sep 2003). "Cloning and sequence analysis of the human cDNA encoding the synaptoporin (delta), a highly conservative synaptic vesicle protein". Mol Biol Rep. 30 (3): 185–91. doi:10.1023/A:1024907723000. PMID 12974474. S2CID 40874195.
↑ "Entrez Gene: SYNPR synaptoporin".

Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948 . PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072 . PMID 11230166.
Singec I, Knoth R, Ditter M, et al. (2002). "Synaptic vesicle protein synaptoporin is differently expressed by subpopulations of mouse hippocampal neurons". J. Comp. Neurol. 452 (2): 139–53. doi:10.1002/cne.10371. PMID 12271488. S2CID 30492933.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Tran MH, Yamada K, Nakajima A, et al. (2004). "Tyrosine nitration of a synaptic protein synaptophysin contributes to amyloid beta-peptide-induced cholinergic dysfunction". Mol. Psychiatry. 8 (4): 407–12. doi:10.1038/sj.mp.4001240. PMID 12740598.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930 . PMID 15489336.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501 . PMID 16381901.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000163630 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000056296 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8034131-5] Leube RE (Aug 1994). "Expression of the synaptophysin gene family is not restricted to neuronal and neuroendocrine differentiation in rat and human". Differentiation. 56 (3): 163–71. doi:10.1046/j.1432-0436.1994.5630163.x. PMID 8034131.

[pmid12974474-6] Dai J, Ji C, Gu S, Wu Q, Wang L, Xu J, Zeng L, Ye X, Yin G, Xie Y, Mao Y (Sep 2003). "Cloning and sequence analysis of the human cDNA encoding the synaptoporin (delta), a highly conservative synaptic vesicle protein". Mol Biol Rep. 30 (3): 185–91. doi:10.1023/A:1024907723000. PMID 12974474. S2CID 40874195.

[entrez-7] "Entrez Gene: SYNPR synaptoporin".

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SYNPR

Related Research Articles

References

Further reading