Sharmila Anandasabapathy | |
|---|---|
 | |
| Alma mater | |
| Known for | Gastrointestinal cancer research |
| Scientific career | |
| Fields | Medicine |
| Institutions | Baylor College of Medicine |
Sharmila Anandasabapathy is a Sri Lankan-American physician and researcher in the field of gastrointestinal cancer. She is a professor of medicine in gastroenterology and serves as director of Baylor Global Health and vice president at the Baylor College of Medicine. [1] [2]
Anandasabapathy pursued a Bachelor of Arts degree in English literature from Yale University. She earned her doctor of medicine (M.D.) degree from the Albert Einstein College of Medicine. [3]
Anandasabapathy was an intern and resident at the New York-Presbyterian Hospital's Weill Cornell Medical Center and Memorial Sloan Kettering Cancer Center for three years. In 2004, she completed her gastroenterology fellowship at Mount Sinai Medical and did advanced training in the endoscopic management of Barrett's esophagus and esophageal cancer. [3] After the fellowship, she joined the faculty at Mount Sinai School of Medicine. She was also a faculty member at the M.D. Anderson Cancer Center for three years between 2005 and 2008. After that, she served as Chief of Endoscopy till 2013 at Mount Sinai Medical Center. Since then, she has been a professor of medicine in gastroenterology at the Baylor College of Medicine. She is also the vice president and director of Baylor Global Health, where she oversees international programs. [4] [5] [6]
Anandasabapathy practices gastroenterology and endoscopy as an attending physician at Baylor-St. Luke's Medical Center. Prior to this, she was attending physician at Mount Sinai Medical Center and the M.D. Anderson Medical Center. [1]
Anandasabapathy's research is focused on the diagnosis and treatment of gastrointestinal cancer using innovative technologies. She has been the principal investigator on multiple grants funded by the National Institutes of Health and National Cancer Institute, through which she has led various clinical trials for the diagnosis of esophageal and gastric cancer. Anandasabapathy has published numerous papers and articles in various journals about gastroenterology and cancer. She has also been involved in the development of guidelines for Barrett's esophagus, which were published in June 2013. [7] [8] [9]
Anandasabapathy's publications and research have been used in advanced imaging technologies for the detection of gastrointestinal cancers. [10] [11] [12]
In 2018, Anandasabapathy and her team at Baylor College of Medicine developed the Emergency Smart Pod, a “rapidly deployable, expandable shipping container-based unit.” It was designed for the management of outbreaks and emergencies globally. [13] [4]
Anandasabapathy was named as one of the "Women on the move" by the Texas Medical Center in 2017. She was featured as USAID female innovator and Influential Women on Houston on International Women's Week. She is also chair of the AGA Women's Committee and associate editor of Gastrointestinal Endoscopy. [14] [15]
Gastroenterology is the branch of medicine focused on the digestive system and its disorders. The digestive system consists of the gastrointestinal tract, sometimes referred to as the GI tract, which includes the esophagus, stomach, small intestine and large intestine as well as the accessory organs of digestion which include the pancreas, gallbladder, and liver. The digestive system functions to move material through the GI tract via peristalsis, break down that material via digestion, absorb nutrients for use throughout the body, and remove waste from the body via defecation. Physicians who specialize in the medical specialty of gastroenterology are called gastroenterologists or sometimes GI doctors. Some of the most common conditions managed by gastroenterologists include gastroesophageal reflux disease, gastrointestinal bleeding, irritable bowel syndrome, inflammatory bowel disease (IBD) which includes Crohn's disease and ulcerative colitis, peptic ulcer disease, gallbladder and biliary tract disease, hepatitis, pancreatitis, colitis, colon polyps and cancer, nutritional problems, and many more.
The esophagus or oesophagus, colloquially known also as the food pipe or gullet, is an organ in vertebrates through which food passes, aided by peristaltic contractions, from the pharynx to the stomach. The esophagus is a fibromuscular tube, about 25 cm (10 in) long in adults, that travels behind the trachea and heart, passes through the diaphragm, and empties into the uppermost region of the stomach. During swallowing, the epiglottis tilts backwards to prevent food from going down the larynx and lungs. The word oesophagus is from Ancient Greek οἰσοφάγος (oisophágos), from οἴσω (oísō), future form of φέρω + ἔφαγον.
Heartburn, also known as pyrosis, cardialgia or acid indigestion, is a burning sensation in the central chest or upper central abdomen. Heartburn is usually due to regurgitation of gastric acid into the esophagus. It is the major symptom of gastroesophageal reflux disease (GERD).
Gastroesophageal reflux disease (GERD) or gastro-oesophageal reflux disease (GORD) is one of the upper gastrointestinal chronic diseases in which stomach content persistently and regularly flows up into the esophagus, resulting in symptoms and/or complications. Symptoms include dental corrosion, dysphagia, heartburn, odynophagia, regurgitation, non-cardiac chest pain, extraesophageal symptoms such as chronic cough, hoarseness, reflux-induced laryngitis, or asthma. In the long term, and when not treated, complications such as esophagitis, esophageal stricture, and Barrett's esophagus may arise.
Barrett's esophagus is a condition in which there is an abnormal (metaplastic) change in the mucosal cells lining the lower portion of the esophagus, from stratified squamous epithelium to simple columnar epithelium with interspersed goblet cells that are normally present only in the small intestine and large intestine. This change is considered to be a premalignant condition because it is associated with a high incidence of further transition to esophageal adenocarcinoma, an often-deadly cancer.
An endoscopy is a procedure used in medicine to look inside the body. The endoscopy procedure uses an endoscope to examine the interior of a hollow organ or cavity of the body. Unlike many other medical imaging techniques, endoscopes are inserted directly into the organ.
Esophagitis, also spelled oesophagitis, is a disease characterized by inflammation of the esophagus. The esophagus is a tube composed of a mucosal lining, and longitudinal and circular smooth muscle fibers. It connects the pharynx to the stomach; swallowed food and liquids normally pass through it.
Esophageal cancer is cancer arising from the esophagus—the food pipe that runs between the throat and the stomach. Symptoms often include difficulty in swallowing and weight loss. Other symptoms may include pain when swallowing, a hoarse voice, enlarged lymph nodes ("glands") around the collarbone, a dry cough, and possibly coughing up or vomiting blood.
Esophagogastroduodenoscopy (EGD) or oesophagogastroduodenoscopy (OGD), also called by various other names, is a diagnostic endoscopic procedure that visualizes the upper part of the gastrointestinal tract down to the duodenum. It is considered a minimally invasive procedure since it does not require an incision into one of the major body cavities and does not require any significant recovery after the procedure. However, a sore throat is common.
Plummer–Vinson syndrome is a rare disease characterized by difficulty swallowing, iron-deficiency anemia, glossitis, cheilosis and esophageal webs. Treatment with iron supplementation and mechanical widening of the esophagus generally provides an excellent outcome.
Gastrointestinal cancer refers to malignant conditions of the gastrointestinal tract and accessory organs of digestion, including the esophagus, stomach, biliary system, pancreas, small intestine, large intestine, rectum and anus. The symptoms relate to the organ affected and can include obstruction, abnormal bleeding or other associated problems. The diagnosis often requires endoscopy, followed by biopsy of suspicious tissue. The treatment depends on the location of the tumor, as well as the type of cancer cell and whether it has invaded other tissues or spread elsewhere. These factors also determine the prognosis.
Endoscopic ultrasound (EUS) or echo-endoscopy is a medical procedure in which endoscopy is combined with ultrasound to obtain images of the internal organs in the chest, abdomen and colon. It can be used to visualize the walls of these organs, or to look at adjacent structures. Combined with Doppler imaging, nearby blood vessels can also be evaluated.
Eosinophilic esophagitis (EoE) is an allergic inflammatory condition of the esophagus that involves eosinophils, a type of white blood cell. In healthy individuals, the esophagus is typically devoid of eosinophils. In EoE, eosinophils migrate to the esophagus in large numbers. When a trigger food is eaten, the eosinophils contribute to tissue damage and inflammation. Symptoms include swallowing difficulty, food impaction, vomiting, and heartburn.
An esophageal food bolus obstruction is a medical emergency caused by the obstruction of the esophagus by an ingested foreign body.
Hashem B. El-Serag is a Palestinian-American physician and medical researcher best known for his research in liver cancer, hepatocellular carcinoma (HCC) and the hepatitis C virus. He serves as the Margaret M. and Albert B. Alkek Chairman of the Department of Medicine at Baylor College of Medicine as well as the Director of the Texas Medical Center Digestive Disease Center. El-Serag previously served as president of the American Gastroenterological Association and Editor-in-Chief of Clinical Gastroenterology and Hepatology.
Chromoendoscopy is a medical procedure wherein dyes are instilled into the gastrointestinal tract at the time of visualization with fibre-optic endoscopy. The purposes of chromoendoscopy is chiefly enhance the characterization of tissues, although dyes may be used for other functional purposes. The detail achieved with chromoendoscopy can often allow for identification of the tissue type or pathology based upon the pattern uncovered.
Endoscopic mucosal resection is a technique used to remove cancerous or other abnormal lesions found in the digestive tract. It is one method of performing a mucosectomy.
Blair S. Lewis, M.D., F.A.C.P., F.A.C.G., is an American board-certified gastroenterologist and Clinical Professor of Medicine at the Mount Sinai School of Medicine. Lewis is a specialist in the field of gastrointestinal endoscopy and was the primary investigator for the first clinical trial of capsule endoscopy for the small intestine and also the first clinical trial of capsule endoscopy for the colon.
Esophageal intramucosal pseudodiverticulosis (EIPD) is a rare condition wherein the wall of the esophagus develops numerous small outpouchings (pseudodiverticulae). Individuals with the condition typically develop difficulty swallowing. The outpouchings represent the ducts of submucosal glands of the esophagus. It typically affects individuals in their sixth and seventh decades of life. While it is associated with certain chronic conditions, particularly alcoholism, diabetes and gastroesophageal reflux disease, the cause of the condition is unknown. Treatment involves medications to treat concomitant conditions such as reflux and esophageal spasm, and dilation of strictures in the esophagus.
Prateek SharmaFACG, FACP, FASGE is an Indian American gastroenterologist that specializes in esophageal diseases and endoscopic treatments.