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References
- ↑ "Synthetic Biological Systems Laboratory".
- ↑ "Columbia University Biomedical Engineering: Tal Danino".
- ↑ "Programming bacteria to detect cancer (and maybe treat it)". TED.com.
- ↑ "Synthetic gene oscillators and their applications".
- ↑ "A synchronized quorum of genetic clocks".
- ↑ Danino, Tal; Prindle, Arthur; Kwong, Gabriel A.; Skalak, Matthew; Li, Howard; Allen, Kaitlin; Hasty, Jeff; Bhatia, Sangeeta N. (2015). "Programmable probiotics for detection of cancer in urine". Science Translational Medicine. 7 (289): 289ra84. doi:10.1126/scitranslmed.aaa3519. PMC 4511399 . PMID 26019220.
- ↑ "Synchronized cycles of bacterial lysis for in vivo delivery".
- ↑ Doshi, Anjali; Shaw, Marian; Tonea, Ruxandra; Moon, Soonhee; Minyety, Rosalía; Doshi, Anish; Laine, Andrew; Guo, Jia; Danino, Tal (July 2023). "Engineered bacterial swarm patterns as spatial records of environmental inputs". Nature Chemical Biology. 19 (7): 878–886. doi:10.1038/s41589-023-01325-2.
- ↑ Deb, Dhruba; Zhu, Shu; LeBlanc, Michael J.; Danino, Tal (November 24, 2022). "Assessing chemotherapy dosing strategies in a spatial cell culture model". Frontiers in Oncology. 12. doi:10.3389/fonc.2022.980770. PMC 9729937 .
- ↑ Gurbatri, Candice R.; Arpaia, Nicholas; Danino, Tal (November 25, 2022). "Engineering bacteria as interactive cancer therapies". Science. 378 (6622): 858–864. doi:10.1126/science.add9667. PMC 10584033 .
- ↑ Deb, Dhruba; Wu, Yangfan; Coker, Courtney; Harimoto, Tetsuhiro; Huang, Ruoqi; Danino, Tal (December 13, 2022). "Design of combination therapy for engineered bacterial therapeutics in non-small cell lung cancer". Scientific Reports. 12 (1). doi:10.1038/s41598-022-26105-1. PMC 9748036 .
- ↑ Savage, Thomas M.; Vincent, Rosa L.; Rae, Sarah S.; Huang, Lei Haley; Ahn, Alexander; Pu, Kelly; Li, Fangda; de los Santos-Alexis, Kenia; Coker, Courtney; Danino, Tal; Arpaia, Nicholas (March 10, 2023). "Chemokines expressed by engineered bacteria recruit and orchestrate antitumor immunity". Science Advances. 9 (10). doi:10.1126/sciadv.adc9436. PMC 9995032 .
- ↑ Serebrinsky-Duek, Kineret; Barra, Maria; Danino, Tal; Garrido, Daniel (April 13, 2023). "Engineered Bacteria for Short-Chain-Fatty-Acid-Repressed Expression of Biotherapeutic Molecules". Microbiology Spectrum. 11 (2). doi:10.1128/spectrum.00049-23. PMC 10101121 .
- ↑ Geller, Leore T.; Barzily-Rokni, Michal; Danino, Tal; Jonas, Oliver H.; Shental, Noam; Nejman, Deborah; Gavert, Nancy; Zwang, Yaara; Cooper, Zachary A.; Shee, Kevin; Thaiss, Christoph A.; Reuben, Alexandre; Livny, Jonathan; Avraham, Roi; Frederick, Dennie T.; Ligorio, Matteo; Chatman, Kelly; Johnston, Stephen E.; Mosher, Carrie M.; Brandis, Alexander; Fuks, Garold; Gurbatri, Candice; Gopalakrishnan, Vancheswaran; Kim, Michael; Hurd, Mark W.; Katz, Matthew; Fleming, Jason; Maitra, Anirban; Smith, David A.; Skalak, Matt; Bu, Jeffrey; Michaud, Monia; Trauger, Sunia A.; Barshack, Iris; Golan, Talia; Sandbank, Judith; Flaherty, Keith T.; Mandinova, Anna; Garrett, Wendy S.; Thayer, Sarah P.; Ferrone, Cristina R.; Huttenhower, Curtis; Bhatia, Sangeeta N.; Gevers, Dirk; Wargo, Jennifer A.; Golub, Todd R.; Straussman, Ravid (September 15, 2017). "Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine". Science. 357 (6356): 1156–1160. doi:10.1126/science.aah5043. hdl: 1721.1/128660 .
- ↑ Ozdemir, Tanel; Fedorec, Alex J.H.; Danino, Tal; Barnes, Chris P. (July 2018). "Synthetic Biology and Engineered Live Biotherapeutics: Toward Increasing System Complexity". Cell Systems. 7 (1): 5–16. doi: 10.1016/j.cels.2018.06.008 .
- ↑ Harimoto, Tetsuhiro; Singer, Zakary S.; Velazquez, Oscar S.; Zhang, Joanna; Castro, Samuel; Hinchliffe, Taylor E.; Mather, William; Danino, Tal (April 30, 2019). "Rapid screening of engineered microbial therapies in a 3D multicellular model". Proceedings of the National Academy of Sciences. 116 (18): 9002–9007. doi:10.1073/pnas.1820824116. PMC 6500119 .
- ↑ Chowdhury, Sreyan; Castro, Samuel; Coker, Courtney; Hinchliffe, Taylor E.; Arpaia, Nicholas; Danino, Tal (July 2019). "Programmable bacteria induce durable tumor regression and systemic antitumor immunity". Nature Medicine. 25 (7): 1057–1063. doi:10.1038/s41591-019-0498-z. PMC 6688650 .
- ↑ Harimoto, Tetsuhiro; Danino, Tal (November 11, 2019). "Engineering bacteria for cancer therapy". Emerging Topics in Life Sciences. 3 (5): 623–629. doi:10.1042/ETLS20190096. PMC 8056215 .
- ↑ Gurbatri, Candice R.; Lia, Ioana; Vincent, Rosa; Coker, Courtney; Castro, Samuel; Treuting, Piper M.; Hinchliffe, Taylor E.; Arpaia, Nicholas; Danino, Tal (February 12, 2020). "Engineered probiotics for local tumor delivery of checkpoint blockade nanobodies". Science Translational Medicine. 12 (530). doi:10.1126/scitranslmed.aax0876. PMC 7685004 .
- ↑ Barra, Maria; Danino, Tal; Garrido, Daniel (March 31, 2020). "Engineered Probiotics for Detection and Treatment of Inflammatory Intestinal Diseases". Frontiers in Bioengineering and Biotechnology. 8. doi:10.3389/fbioe.2020.00265. PMC 7137092 .
- ↑ Chien, Tiffany; Jones, Drew R.; Danino, Tal (January 15, 2021). "Engineered Bacterial Production of Volatile Methyl Salicylate". ACS Synthetic Biology. 10 (1): 204–208. doi:10.1021/acssynbio.0c00497.
- ↑ Singer, Zakary S.; Ambrose, Pradeep M.; Danino, Tal; Rice, Charles M. (March 2021). "Quantitative measurements of early alphaviral replication dynamics in single cells reveals the basis for superinfection exclusion". Cell Systems. 12 (3): 210–219.e3. doi:10.1016/j.cels.2020.12.005. PMC 9143976 .
- ↑ Chien, Tiffany; Harimoto, Tetsuhiro; Kepecs, Benjamin; Gray, Kelsey; Coker, Courtney; Hou, Nicholas; Pu, Kelly; Azad, Tamjeed; Nolasco, Andoni; Pavlicova, Martina; Danino, Tal (July 29, 2021). "Enhancing the tropism of bacteria via genetically programmed biosensors". Nature Biomedical Engineering. 6 (1): 94–104. doi:10.1038/s41551-021-00772-3. PMC 8956018 .
- ↑ Harimoto, Tetsuhiro; Hahn, Jaeseung; Chen, Yu-Yu; Im, Jongwon; Zhang, Joanna; Hou, Nicholas; Li, Fangda; Coker, Courtney; Gray, Kelsey; Harr, Nicole; Chowdhury, Sreyan; Pu, Kelly; Nimura, Clare; Arpaia, Nicholas; Leong, Kam W.; Danino, Tal (August 2022). "A programmable encapsulation system improves delivery of therapeutic bacteria in mice". Nature Biotechnology. 40 (8): 1259–1269. doi:10.1038/s41587-022-01244-y. PMC 9371971 .
- ↑ Harimoto, Tetsuhiro; Deb, Dhruba; Danino, Tal (October 2022). "A rapid screening platform to coculture bacteria within tumor spheroids". Nature Protocols. 17 (10): 2216–2239. doi:10.1038/s41596-022-00723-5. PMC 10332800 .
- ↑ "Gates Foundation Uses Art to Encourage Vaccination". The New York Times .
- ↑ "At M.I.T., Science Embraces a New Chaos Theory: Art". The New York Times .
- ↑ "The Devil Wears Pulsars". The Atlantic .
- ↑ "A Beautiful Wallpaper Made With Smallpox Vaccine".
- ↑ Project, The Creators (August 19, 2014). "[Video] Colonies | Vik Muniz And Tal Danino Turn Living Cells Into Art". Vice.
- ↑ Stamler, Hannah (March 17, 2015). "The Sights (and Smells) of Anicka Yi's Bacteria Art Show". Vice.
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