Interstate 40 (I-40) is a major east–west transcontinental Interstate Highway in the southeastern and southwestern portions of the United States. At a length of 2,556.61 miles (4,114.46 km), it is the third-longest Interstate Highway in the country, after I-90 and I-80. From west to east, it passes through California, Arizona, New Mexico, Texas, Oklahoma, Arkansas, Tennessee, and North Carolina. Its western end is at I-15 in Barstow, California, while its eastern end is at a concurrency with U.S. Route 117 (US 117) and North Carolina Highway 132 (NC 132) in Wilmington, North Carolina. Major cities served by the interstate include Flagstaff, Arizona; Albuquerque, New Mexico; Amarillo, Texas; Oklahoma City, Oklahoma; Little Rock, Arkansas; Memphis, Nashville, and Knoxville in Tennessee; and Asheville, Winston-Salem, Greensboro, Durham, Raleigh, and Wilmington in North Carolina.
Interstate 55 (I-55) is a major Interstate Highway in the central United States. As with most primary Interstates that end in a five, it is a major cross-country, north–south route, connecting the Gulf of Mexico to the Great Lakes. The highway travels from LaPlace, Louisiana, at I-10 to Chicago, Illinois, at U.S. Route 41, at McCormick Place. The major cities that I-55 connects to are New Orleans, Louisiana; Jackson, Mississippi; Memphis, Tennessee; St. Louis, Missouri; and Chicago, Illinois.
Interstate 69 (I-69) is an Interstate Highway in the United States currently consisting of 10 unconnected segments with an original continuous segment from Indianapolis, Indiana, northeast to the Canadian border in Port Huron, Michigan, at 355.8 miles (572.6 km). The remaining separated segments are variously completed and posted or not posted sections of an extension southwest to the Mexican border in Texas. Of this extension—nicknamed the NAFTA Superhighway because it would help trade with Canada and Mexico spurred by the North American Free Trade Agreement (NAFTA)—five pieces near Corpus Christi, Texas; Houston, Texas; northwestern Mississippi; Memphis, Tennessee; and Evansville, Indiana, have been built or upgraded and signposted as I-69. A sixth segment of I-69 through Kentucky utilizing that state's existing parkway system and a section of I-24 was established by federal legislation in 2008. This brings the total length to about 720 miles (1,160 km).
U.S. Route 79 is a United States highway in the Southern United States. The route is officially considered and labeled as a north-south highway, but its path is actually more of a diagonal northeast-southwest highway. The highway's northern/eastern terminus is in Russellville, Kentucky, at an intersection with U.S. Route 68 and KY 80. Its southern/western terminus is in Round Rock, Texas, at an interchange with Interstate 35, ten miles (16 km) north of Austin. US 79, US 68, and Interstate 24/US 62 are the primary east–west access points for the Land Between the Lakes recreation area straddling the Kentucky/Tennessee border.
U.S. Route 70 or U.S. Highway 70 is an east–west United States highway that runs for 2,381 miles (3,832 km) from eastern North Carolina to east-central Arizona. It is a major east–west highway of the Southeastern, Southern and Southwestern United States. Established as one of the original highways of 1926, it originally ran only to Holbrook, Arizona, then was extended in 1934 as a coast to coast route, with the current Eastern terminus near the Atlantic Ocean in Atlantic, North Carolina, and the former Western terminus near the Pacific Ocean in Los Angeles, California. The current Western terminus was then truncated to US 60 / SR 77 in Globe, Arizona. Before the completion of the Interstate system, U.S. Highway 70 was sometimes referred to as the "Broadway of America", due to its status as one of the main east–west thoroughfares in the nation. It was also promoted as the "Treasure Trail" by the U.S. Highway 70 Association as of 1951.
Interstate 640 (I-640) is an east–west auxiliary Interstate Highway in Knoxville, Tennessee. It serves as a bypass for I-40 around Downtown Knoxville and is also an alternative route for traffic passing between I-40 and I-75. All trucks carrying hazardous cargo through Knoxville are required to use I-640. It has a total length of 10.80 miles (17.38 km) and runs approximately three miles (4.8 km) north of downtown through the northern neighborhoods of Knoxville.
State Route 1, known as the Memphis to Bristol Highway, is a 538.8-mile-long (867.1 km) mostly-unsigned state highway in the U.S. state of Tennessee. It stretches all the way from the Arkansas state line at Memphis in the southwest corner of the state to Bristol in the northeast part. Most of the route travels concurrently with U.S. Route 70 and US 11W. It is the longest highway of any kind in the state of Tennessee. The route is signed as both in the state of Tennessee, a Primary and Secondary Highway
Interstate 240 (I-240) is a 19.27-mile-long (31.01 km) auxiliary Interstate Highway in the US state of Tennessee that forms a bypass around the southern and eastern neighborhoods of Memphis. Combined, I-240 and its parent, I-40, form a contiguous beltway around most of Memphis. I-240 runs from I-40 in Midtown Memphis to I-40 and Sam Cooper Boulevard in East Memphis. Throughout its length, it provides access to I-55, multiple U.S. and state routes, and the Memphis International Airport. The segment between the western terminus and I-55 is a north–south route, and the segment between I-55 and the eastern terminus runs east to west. Throughout its length, I-240 is designated as the Dr. Martin Luther King Jr. Expressway, the W.B. Fowler Sr. Expressway, and the Avron B. Fogelman Expressway.
State Route 385 (SR 385) is the designation for two non-contiguous segments of east–west controlled-access highway in the Memphis metropolitan area in Shelby County, Tennessee, separated by a section of Interstate 269 (I-269). The northern section, designated as Paul W. Barret Parkway runs between U.S. Route 51 in Millington and I-40 in Arlington, both of which are suburbs of Memphis. The southern segment, known as Bill Morris Parkway, runs between I-240 in southeastern Memphis, and I-269 in Collierville, and also serves the city of Germantown. The northern segment, combined with I-269, serves as a partial outer beltway around Memphis, and the southern segment serves as a spur route between the city and its southeastern suburbs, and is notable for its almost-exclusive use of single-point urban interchanges (SPUIs).
U.S. Route 51 (US 51), mostly overlapped by the unsigned State Route 3 (SR 3), is a north–south state highway in the U.S. state of Tennessee, that is 135.9 miles (218.71 km) long, completely within West Tennessee. It begins in Shelby County and ends in Obion County. The SR 3 designation is seen largely on mileposts.
Interstate 55 (I-55) in Tennessee lies entirely within the city of Memphis, located in Shelby County. The highway enters the city from Southaven in Desoto County, Mississippi, and passes through the Whitehaven area of the city, bypassing Memphis International Airport to the west.
State Route 23 is an east–west major arterial urban highway running from Bellevue Boulevard near downtown Memphis to Interstate 240 near Shelby Farms in Shelby County, Tennessee.
Interstate 40 (I-40) is part of the Interstate Highway System that spans 2,556.61 miles (4,114.46 km) from Barstow, California, to Wilmington, North Carolina. In Tennessee, I-40 traverses the state from west to east, from the Mississippi River at the Arkansas border to the northern base of the Great Smoky Mountains at the North Carolina border. At 455.28 miles (732.70 km), the Tennessee segment of I-40 is the longest of the eight states through which it passes, and the longest Interstate Highway in Tennessee.
Interstate 69 (I-69) is a proposed US Interstate Highway that will pass through the western part of the US state of Tennessee, serving the cities of Union City, Dyersburg, and Memphis. State officials have considered building parts of I-69 as a toll road. Currently, a 21-mile (34 km) section of already-existing freeway in Memphis has been approved for the I-69 designation and a section near Union City is also under construction and scheduled to be completed in Summer 2023.
Sam Cooper Boulevard is an urban highway in Memphis, Tennessee, United States. The more recent western segment of the road follows a parkway design, while the older eastern portion, which was proposed and constructed as a segment of Interstate 40 (I-40), is built as a freeway, without at-grade intersections and traffic lights. The western terminus of Sam Cooper Boulevard is at East Parkway North. At the western termination point of the road there is a short concurrency of East Parkway North with U.S. Route 64 (US 64), US 70, and US 79. From its western end, Sam Cooper Boulevard continues east for 5.8 miles (9.3 km) to reach its eastern terminus at the I-40/I-240 interchange.
In Tennessee, U.S. Route 412 stretches for 181.93 miles (292.79 km) through the farmland of West Tennessee and the hills of Middle Tennessee, starting at the Missouri state line near Dyersburg and running to an interchange between I-65 and SR 99 in Columbia.
In Tennessee, U.S. Route 64 stretches 404.1 miles (650.3 km) from the Mississippi River in Memphis to the North Carolina state line near Ducktown. The highway, along with US 72, is a major route for travel between Memphis and Chattanooga.
State Route 388 (SR 388) is a four-lane divided highway in Shelby County, Tennessee. The route connects the Frayser neighborhood of Memphis with Northaven and Shelby Forest. The entire route is known locally as North Watkins Street.
State Route 277, also known as Airways Boulevard and East Parkway, is a major north–south urban state highway in Memphis, Shelby County, Tennessee.
US 51 in Memphis 
I-40 in Memphis
