Formamidase

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formamidase
2e2l2.jpg
Formamidase hexamer, Helicobacter pylori
Identifiers
EC no. 3.5.1.49
CAS no. 9013-59-6
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO
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PMC articles
PubMed articles
NCBI proteins

In enzymology, a formamidase (EC 3.5.1.49) is an enzyme that catalyzes the chemical reaction

formamide + H2O formate + NH3

Thus, the two substrates of this enzyme are formamide and H2O, whereas its two products are formate and NH3.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is formamide amidohydrolase. This enzyme participates in glyoxylate and dicarboxylate metabolism and nitrogen metabolism.

Structural studies

As of late 2007, four structures have been solved for this class of enzymes, with PDB accession codes 2DYU, 2DYV, 2E2K, and 2E2L.

Related Research Articles

<span class="mw-page-title-main">Ammonium formate</span> Chemical compound

Ammonium formate, NH4HCO2, is the ammonium salt of formic acid. It is a colorless, hygroscopic, crystalline solid.

<span class="mw-page-title-main">Amidase</span>

In enzymology, an amidase (EC 3.5.1.4, acylamidase, acylase (misleading), amidohydrolase (ambiguous), deaminase (ambiguous), fatty acylamidase, N-acetylaminohydrolase (ambiguous)) is an enzyme that catalyzes the hydrolysis of an amide. In this way, the two substrates of this enzyme are an amide and H2O, whereas its two products are monocarboxylate and NH3.

In enzymology, an arylformamidase (EC 3.5.1.9) is an enzyme that catalyzes the chemical reaction

In enzymology, a beta-ureidopropionase (EC 3.5.1.6) is an enzyme that catalyzes the chemical reaction

In enzymology, a carnitinamidase (EC 3.5.1.73) is an enzyme that catalyzes the chemical reaction

In enzymology, a D-glutaminase (EC 3.5.1.35) is an enzyme that catalyzes the chemical reaction

In enzymology, a formylmethionine deformylase (EC 3.5.1.31) is an enzyme that catalyzes the chemical reaction

In enzymology, a glutamin-(asparagin-)ase (EC 3.5.1.38) is an enzyme that catalyzes the chemical reaction

In enzymology, a glutathionylspermidine amidase (EC 3.5.1.78) is an enzyme that catalyzes the chemical reaction

In enzymology, a mandelamide amidase (EC 3.5.1.86) is an enzyme that catalyzes the chemical reaction

In enzymology, a N-carbamoylputrescine amidase (EC 3.5.1.53) is an enzyme that catalyzes the chemical reaction

In enzymology, a N-carbamoylsarcosine amidase (EC 3.5.1.59) is an enzyme that catalyzes the chemical reaction

In enzymology, a N-formylglutamate deformylase (EC 3.5.1.68) is an enzyme that catalyzes the chemical reaction

In enzymology, a N-formylmethionylaminoacyl-tRNA deformylase (EC 3.5.1.27) is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">Nicotinamidase</span>

In enzymology, a nicotinamidase (EC 3.5.1.19) is an enzyme that catalyzes the chemical reaction

In enzymology, a nicotinamide-nucleotide amidase (EC 3.5.1.42) is an enzyme that catalyzes the chemical reaction

In enzymology, a N,N-dimethylformamidase (EC 3.5.1.56) is an enzyme that catalyzes the chemical reaction

In enzymology, a N-substituted formamide deformylase (EC 3.5.1.91) is an enzyme that catalyzes the chemical reaction

<span class="mw-page-title-main">Omega-amidase</span>

In enzymology, an omega-amidase (EC 3.5.1.3) is an enzyme that catalyzes the chemical reaction

In enzymology, a pentanamidase (EC 3.5.1.50) is an enzyme that catalyzes the chemical reaction

References


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