James S. Clegg

Last updated
James Clegg
Born
James Standish Clegg

(1933-07-27) July 27, 1933 (age 90) [1] [2]
Alma mater Pennsylvania State University (BS)
Johns Hopkins University (PhD)
Awards Phi Beta Kappa (1958)
Fellow of the AAAS (1985)
Scientific career
Fields Biochemistry [3]
Cryptobiosis [4]
Institutions University of California, Davis
University of Miami
Thesis The physiology of blood trehalose and its function during flight in the blowfly  (1961)
Website biology.ucdavis.edu/people/james-clegg

James Standish Clegg (born 1933) [1] is a Professor Emeritus of Biochemistry at University of California, Davis, [3] [5] based at the Coastal and Marine Sciences Institute (CMSI) in Bodega Bay, California. [4] He served as director of the Bodega Marine Laboratory (BML) from 1986 to 1999 and as president of the National Association Marine Laboratories (NAML) from 1991 to 1993. [6] [7]

Contents

Education

Clegg received his Bachelor of Science degree from Pennsylvania State University in Zoology in 1958 [6] and his PhD from Johns Hopkins University in 1961 for research investigating the physiology of blood trehalose and its function during flight in the blowfly. [8] [9]

Research and career

After his PhD, Clegg was a postdoctoral researcher with David R. Evans from 1961 to 1962. [10] At the National Institutes of Health (NIH) Clegg was a predoctoral fellow and postdoctoral fellow from 1960 to 1962. [6] He was a professor at University of Miami [11] [12] from 1963 to 1986 and UC Davis from 1986. [13] He has been a visiting scientist at Oak Ridge National Laboratory (ORNL) in 1966, the Centre national de la recherche scientifique (CNRS, Paris), and University College of Wales in Aberystwyth, United Kingdom in 1990 and Ghent University in 1999. [6]

Clegg's research interests are biochemical and biophysical adaptations to environmental extremes (extremophiles); stress proteins and molecular chaperones in invertebrates; organization of enzymes and metabolic activity in the aqueous compartments of cells [14] and the physical properties of intracellular water. [3] [6] His research used brine shrimp and Artemia salina as model organism. [7] [12] [11]

Awards and honors

Clegg was awarded Phi Beta Kappa (ΦΒΚ) from Pennsylvania State University in 1958. Clegg was a Woodrow Wilson fellow at the Johns Hopkins University from 1958 to 1959. [6] He was a Fulbright Program senior research fellow at the University of London in 1978 and again at Ghent University, Belgium in 1999. He was elected Fellow of the American Association for the Advancement of Science (FAAAS) in 1985. [6]

Related Research Articles

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<span class="mw-page-title-main">Rete mirabile</span> Complex of arteries and veins lying very close to each other

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<span class="mw-page-title-main">Brine shrimp</span> Genus of aquatic crustaceans

Artemia is a genus of aquatic crustaceans also known as brine shrimp. It is the only genus in the family Artemiidae. The first historical record of the existence of Artemia dates back to the first half of the 10th century AD from Lake Urmia, Iran, with an example called by an Iranian geographer an "aquatic dog", although the first unambiguous record is the report and drawings made by Schlösser in 1757 of animals from Lymington, England. Artemia populations are found worldwide, typically in inland saltwater lakes, but occasionally in oceans. Artemia are able to avoid cohabiting with most types of predators, such as fish, by their ability to live in waters of very high salinity.

<span class="mw-page-title-main">Trehalose</span> Chemical compound

Trehalose is a sugar consisting of two molecules of glucose. It is also known as mycose or tremalose. Some bacteria, fungi, plants and invertebrate animals synthesize it as a source of energy, and to survive freezing and lack of water.

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References

  1. 1 2 James S. Clegg at Library of Congress
  2. Ancestry.com. U.S., Public Records Index, 1950-1993, Volume 2 [database on-line]. Lehi, UT, USA: Ancestry.com Operations, Inc., 2010. Voter Registration Lists, Public Record Filings, Historical Residential Records, and Other Household Database Listings.
  3. 1 2 3 James S. Clegg publications indexed by Google Scholar OOjs UI icon edit-ltr-progressive.svg
  4. 1 2 Clegg, James S. (2001). "Cryptobiosis — a peculiar state of biological organization". Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. 128 (4): 613–624. doi:10.1016/S1096-4959(01)00300-1. ISSN   1096-4959. PMID   11290443. Closed Access logo transparent.svg
  5. James S. Clegg publications indexed by the Scopus bibliographic database. (subscription required)
  6. 1 2 3 4 5 6 7 Anon (2018). "James S. Clegg: Emeritus Professor". biology.ucdavis.edu. University of California, Davis. Archived from the original on 2018-03-02.
  7. 1 2 Clegg, James S. (1997). "Embryos of Artemia franciscana survive four years of continuous anoxia: The case for complete metabolic rate depression". Journal of Experimental Biology. 200 (3): 467–475. doi: 10.1242/jeb.200.3.467 . PMID   9318130. Lock-green.svg
  8. Clegg, James Standish (1961). The physiology of blood trehalose and its function during flight in the blowfly. jhu.edu (PhD thesis). Johns Hopkins University. OCLC   30555269.
  9. Clegg, James S.; Evans, David R. (1961). "The Physiology of Blood Trehalose and its Function During Flight in the Blowfly". The Journal of Experimental Biology . The Company of Biologists. 38 (4): 771–792. doi:10.1242/jeb.38.4.771. Lock-green.svg
  10. Clegg, James S.; Evans, David R. (1961). "Blood Trehalose and Flight Metabolism in the Blowfly". Science . 134 (3471): 54–55. Bibcode:1961Sci...134...54C. doi:10.1126/science.134.3471.54. ISSN   0036-8075. PMID   13694011. S2CID   35762256. Closed Access logo transparent.svg
  11. 1 2 Clegg, James S. (1964). "The Control of Emergence and Metabolism by External Osmotic Pressure and the Role of Free Glycerol in Developing Cysts of Artemia salina". Journal of Experimental Biology. 41 (4): 879–892. doi:10.1242/jeb.41.4.879. PMID   14239915. Lock-green.svg
  12. 1 2 Clegg, James S. (1965). "The origin of trehalose and its significance during the formation of encysted dormant embryos of Artemia salina". Comparative Biochemistry and Physiology. 14 (1): 135–143. doi:10.1016/0010-406X(65)90014-9. ISSN   0010-406X. PMID   14288194. Closed Access logo transparent.svg
  13. Clegg, James; Kell, Douglas; Knull, Harvey; Welch, G.Rickey; Wilson, John (2001). "Macromolecular interactions: tracing the roots". Trends in Biochemical Sciences. 26 (2): 91. doi:10.1016/S0968-0004(00)01739-4. ISSN   0968-0004. PMID   11327044. Closed Access logo transparent.svg
  14. Clegg, James S. (1984). "Properties and metabolism of the aqueous cytoplasm and its boundaries". American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 246 (2): R133–R151. doi:10.1152/ajpregu.1984.246.2.R133. ISSN   0363-6119. PMID   6364846. S2CID   30351411. Lock-green.svg