The 1922 College Baseball All-Southern Team consists of baseball players selected at their respective positions after the 1922 NCAA baseball season.
| Position | Name | School | Notes |
|---|---|---|---|
| Pitcher | Jack Frost | Georgia | CW, MB |
| Tige Stone | Mercer | ||
| Collins | Georgia Tech | ||
| Jim Joe Edwards | Mississippi College | ||
| Cliff Pantone | Georgia | CW | |
| Freddy Sale | MB | ||
| Catcher | Charlie Gibson | Auburn | CW, MB |
| Cotton Klindworth | Mississippi A&M | ||
| First baseman | Chief Cody | Georgia | |
| Second baseman | Richardson | Auburn | |
| Third baseman | Eddie Morgan | Georgia Tech | CW |
| Hall | Alabama | MB | |
| Shortstop | Doc Kuhn | Vanderbilt | CW, MB |
| Outfielder | Sox Ingram | Georgia Tech | |
| Red Barron | |||
| J. D. Thomason | Georgia | ||
| Utility | George Clarke | MB |